Tobacco smoking leads to extensive genome-wide changes in DNA methylation
Zeilinger, Sonja, Kühnel, Brigitte, Klopp, Norman, Baurecht, Hansjörg, Kleinschmidt, Anja, Gieger, Christian, Weidinger, Stephan, Lattka, Eva, Adamski, Jerzy, Peters, Annette, Strauch, Konstantin, Waldenberger, Melanie, Illig, Thomas
Published in PloS one (17.05.2013)
Published in PloS one (17.05.2013)
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Connecting genetic risk to disease end points through the human blood plasma proteome
Suhre, Karsten, Arnold, Matthias, Bhagwat, Aditya Mukund, Cotton, Richard J, Engelke, Rudolf, Raffler, Johannes, Sarwath, Hina, Thareja, Gaurav, Wahl, Annika, DeLisle, Robert Kirk, Gold, Larry, Pezer, Marija, Lauc, Gordan, El-Din Selim, Mohammed A, Mook-Kanamori, Dennis O, Al-Dous, Eman K, Mohamoud, Yasmin A, Malek, Joel, Strauch, Konstantin, Grallert, Harald, Peters, Annette, Kastenmüller, Gabi, Gieger, Christian, Graumann, Johannes
Published in Nature communications (27.02.2017)
Published in Nature communications (27.02.2017)
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Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease
Yao, Chen, Chen, George, Song, Ci, Keefe, Joshua, Mendelson, Michael, Huan, Tianxiao, Sun, Benjamin B, Laser, Annika, Maranville, Joseph C, Wu, Hongsheng, Ho, Jennifer E, Courchesne, Paul, Lyass, Asya, Larson, Martin G, Gieger, Christian, Graumann, Johannes, Johnson, Andrew D, Danesh, John, Runz, Heiko, Hwang, Shih-Jen, Liu, Chunyu, Butterworth, Adam S, Suhre, Karsten, Levy, Daniel
Published in Nature communications (15.08.2018)
Published in Nature communications (15.08.2018)
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DNA methylation and body-mass index: a genome-wide analysis
Dick, Katherine J, PhD, Nelson, Christopher P, PhD, Tsaprouni, Loukia, PhD, Sandling, Johanna K, PhD, Aïssi, Dylan, MSc, Wahl, Simone, MSc, Meduri, Eshwar, PhD, Morange, Pierre-Emmanuel, Prof, Gagnon, France, PhD, Grallert, Harald, PhD, Waldenberger, Melanie, PhD, Peters, Annette, Prof, Erdmann, Jeanette, Prof, Hengstenberg, Christian, Prof, Cambien, Francois, Prof, Goodall, Alison H, Prof, Ouwehand, Willem H, Prof, Schunkert, Heribert, Prof, Thompson, John R, Prof, Spector, Tim D, FRCP, Gieger, Christian, PhD, Trégouët, David-Alexandre, PhD, Deloukas, Panos, Prof, Samani, Nilesh J, Prof
Published in The Lancet (British edition) (07.06.2014)
Published in The Lancet (British edition) (07.06.2014)
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Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease
Tzoulaki, Ioanna, Castagné, Raphaële, Boulangé, Claire L, Karaman, Ibrahim, Chekmeneva, Elena, Evangelou, Evangelos, Ebbels, Timothy M D, Kaluarachchi, Manuja R, Chadeau-Hyam, Marc, Mosen, David, Dehghan, Abbas, Moayyeri, Alireza, Ferreira, Diana L Santos, Guo, Xiuqing, Rotter, Jerome I, Taylor, Kent D, Kavousi, Maryam, de Vries, Paul S, Lehne, Benjamin, Loh, Marie, Hofman, Albert, Nicholson, Jeremy K, Chambers, John, Gieger, Christian, Holmes, Elaine, Tracy, Russell, Kooner, Jaspal, Greenland, Philip, Franco, Oscar H, Herrington, David, Lindon, John C, Elliott, Paul
Published in European heart journal (07.09.2019)
Published in European heart journal (07.09.2019)
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Revealing the role of the human blood plasma proteome in obesity using genetic drivers
Zaghlool, Shaza B, Sharma, Sapna, Molnar, Megan, Matías-García, Pamela R, Elhadad, Mohamed A, Waldenberger, Melanie, Peters, Annette, Rathmann, Wolfgang, Graumann, Johannes, Gieger, Christian, Grallert, Harald, Suhre, Karsten
Published in Nature communications (24.02.2021)
Published in Nature communications (24.02.2021)
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Impact of long-term storage and freeze-thawing on eight circulating microRNAs in plasma samples
Matias-Garcia, Pamela R, Wilson, Rory, Mussack, Veronika, Reischl, Eva, Waldenberger, Melanie, Gieger, Christian, Anton, Gabriele, Peters, Annette, Kuehn-Steven, Andrea
Published in PloS one (14.01.2020)
Published in PloS one (14.01.2020)
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A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population
Sekula, Peggy, Goek, Oemer-Necmi, Quaye, Lydia, Barrios, Clara, Levey, Andrew S, Römisch-Margl, Werner, Menni, Cristina, Yet, Idil, Gieger, Christian, Inker, Lesley A, Adamski, Jerzy, Gronwald, Wolfram, Illig, Thomas, Dettmer, Katja, Krumsiek, Jan, Oefner, Peter J, Valdes, Ana M, Meisinger, Christa, Coresh, Josef, Spector, Tim D, Mohney, Robert P, Suhre, Karsten, Kastenmüller, Gabi, Köttgen, Anna
Published in Journal of the American Society of Nephrology (01.04.2016)
Published in Journal of the American Society of Nephrology (01.04.2016)
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Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study
Chambers, John C, Dr, Loh, Marie, PhD, Lehne, Benjamin, PhD, Drong, Alexander, PhD, Kriebel, Jennifer, PhD, Motta, Valeria, PhD, Wahl, Simone, MSc, Elliott, Hannah R, Dip Biol, Rota, Federica, PhD, Scott, William R, MRCP, Zhang, Weihua, PhD, Tan, Sian-Tsung, MRCP, Campanella, Gianluca, MSc, Chadeau-Hyam, Marc, PhD, Yengo, Loic, PhD, Richmond, Rebecca C, BA, Adamowicz-Brice, Martyna, PhD, Afzal, Uzma, MRCP, Bozaoglu, Kiymet, PhD, Mok, Zuan Yu, BSc, Ng, Hong Kiat, BSc, Pattou, François, Prof, Prokisch, Holger, PhD, Rozario, Michelle Ann, BSc, Tarantini, Letizia, PhD, Abbott, James, PhD, Ala-Korpela, Mika, Prof, Albetti, Benedetta, PhD, Ammerpohl, Ole, Prof, Bertazzi, Pier Alberto, Prof, Blancher, Christine, PhD, Caiazzo, Robert, PhD, Danesh, John, Prof, Gaunt, Tom R, FRCP, de Lusignan, Simon, Prof, Gieger, Christian, PhD, Illig, Thomas, Prof, Jha, Sujeet, MRCP, Jones, Simon, Prof, Jowett, Jeremy, PhD, Kangas, Antti J, MSc, Kasturiratne, Anuradhani, MD, Kato, Norihiro, PhD, Kotea, Navaratnam, PhD, Kowlessur, Sudhir, Dip Pub Health Admin, Pitkäniemi, Janne, PhD, Punjabi, Prakash, FRCS, Saleheen, Danish, PhD, Schafmayer, Clemens, Prof, Soininen, Pasi, PhD, Tai, E-Shyong, PhD, Thorand, Barbara, PhD, Tuomilehto, Jaakko, Prof, Wickremasinghe, Ananda Rajitha, Prof, Kyrtopoulos, Soterios A, Prof, Aitman, Timothy J, Prof, Herder, Christian, PhD, Hampe, Jochen, Prof, Cauchi, Stéphane, PhD, Relton, Caroline L, Prof, Froguel, Philippe, Prof, Soong, Richie, PhD, Vineis, Paolo, Prof, Jarvelin, Marjo-Riitta, Prof, Scott, James, Prof, Grallert, Harald, PhD, Bollati, Valentina, PhD, Elliott, Paul, Prof, McCarthy, Mark I, Prof, Kooner, Jaspal S, Prof
Published in The lancet. Diabetes & endocrinology (01.07.2015)
Published in The lancet. Diabetes & endocrinology (01.07.2015)
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Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach
MENNI, Cristina, FAUMAN, Eric, WEI YUAN, MILBURN, Mike, PALMER, Colin N. A, FRAYLING, Timothy M, TRIMMER, Jeff, BELL, Jordana T, GIEGER, Christian, MOHNEY, Rob P, BROSNAN, Mary Julia, SUHRE, Karsten, ERTE, Idil, SORANZO, Nicole, SPECTOR, Tim D, PERRY, John R. B, KASTENMÜLLER, Gabi, SHIN, So-Youn, PETERSEN, Ann-Kristin, HYDE, Craig, PSATHA, Maria, WARD, Kirsten J
Published in Diabetes (New York, N.Y.) (01.12.2013)
Published in Diabetes (New York, N.Y.) (01.12.2013)
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A polygenic and family risk score are both independently associated with risk of type 2 diabetes in a population-based study
Duschek, Elena, Forer, Lukas, Schönherr, Sebastian, Gieger, Christian, Peters, Annette, Kronenberg, Florian, Grallert, Harald, Lamina, Claudia
Published in Scientific reports (23.03.2023)
Published in Scientific reports (23.03.2023)
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A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms[S]
Mack, Salome, Coassin, Stefan, Rueedi, Rico, Yousri, Noha A., Seppälä, Ilkka, Gieger, Christian, Schönherr, Sebastian, Forer, Lukas, Erhart, Gertraud, Marques-Vidal, Pedro, Ried, Janina S., Waeber, Gerard, Bergmann, Sven, Dähnhardt, Doreen, Stöckl, Andrea, Raitakari, Olli T., Kähönen, Mika, Peters, Annette, Meitinger, Thomas, Strauch, Konstantin, Kedenko, Ludmilla, Paulweber, Bernhard, Lehtimäki, Terho, Hunt, Steven C., Vollenweider, Peter, Lamina, Claudia, Kronenberg, Florian
Published in Journal of lipid research (01.09.2017)
Published in Journal of lipid research (01.09.2017)
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Human serum metabolic profiles are age dependent
Yu, Zhonghao, Zhai, Guangju, Singmann, Paula, He, Ying, Xu, Tao, Prehn, Cornelia, Römisch‐Margl, Werner, Lattka, Eva, Gieger, Christian, Soranzo, Nicole, Heinrich, Joachim, Standl, Marie, Thiering, Elisabeth, Mittelstraß, Kirstin, Wichmann, Heinz‐Erich, Peters, Annette, Suhre, Karsten, Li, Yixue, Adamski, Jerzy, Spector, Tim D., Illig, Thomas, Wang‐Sattler, Rui
Published in Aging cell (01.12.2012)
Published in Aging cell (01.12.2012)
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Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting
Suhre, Karsten, Meisinger, Christa, Döring, Angela, Altmaier, Elisabeth, Belcredi, Petra, Gieger, Christian, Chang, David, Milburn, Michael V, Gall, Walter E, Weinberger, Klaus M, Mewes, Hans-Werner, Hrabé de Angelis, Martin, Wichmann, H-Erich, Kronenberg, Florian, Adamski, Jerzy, Illig, Thomas
Published in PloS one (11.11.2010)
Published in PloS one (11.11.2010)
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Discovery of sexual dimorphisms in metabolic and genetic biomarkers
Mittelstrass, Kirstin, Ried, Janina S, Yu, Zhonghao, Krumsiek, Jan, Gieger, Christian, Prehn, Cornelia, Roemisch-Margl, Werner, Polonikov, Alexey, Peters, Annette, Theis, Fabian J, Meitinger, Thomas, Kronenberg, Florian, Weidinger, Stephan, Wichmann, Heinz Erich, Suhre, Karsten, Wang-Sattler, Rui, Adamski, Jerzy, Illig, Thomas
Published in PLoS genetics (01.08.2011)
Published in PLoS genetics (01.08.2011)
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The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers
Wilson, Rory, Wahl, Simone, Pfeiffer, Liliane, Ward-Caviness, Cavin K, Kunze, Sonja, Kretschmer, Anja, Reischl, Eva, Peters, Annette, Gieger, Christian, Waldenberger, Melanie
Published in BMC genomics (18.10.2017)
Published in BMC genomics (18.10.2017)
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Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits
Zaghlool, Shaza B, Kühnel, Brigitte, Elhadad, Mohamed A, Kader, Sara, Halama, Anna, Thareja, Gaurav, Engelke, Rudolf, Sarwath, Hina, Al-Dous, Eman K, Mohamoud, Yasmin A, Meitinger, Thomas, Wilson, Rory, Strauch, Konstantin, Peters, Annette, Mook-Kanamori, Dennis O, Graumann, Johannes, Malek, Joel A, Gieger, Christian, Waldenberger, Melanie, Suhre, Karsten
Published in Nature communications (03.01.2020)
Published in Nature communications (03.01.2020)
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Gender-specific pathway differences in the human serum metabolome
Krumsiek, Jan, Mittelstrass, Kirstin, Do, Kieu Trinh, Stückler, Ferdinand, Ried, Janina, Adamski, Jerzy, Peters, Annette, Illig, Thomas, Kronenberg, Florian, Friedrich, Nele, Nauck, Matthias, Pietzner, Maik, Mook-Kanamori, Dennis O., Suhre, Karsten, Gieger, Christian, Grallert, Harald, Theis, Fabian J., Kastenmüller, Gabi
Published in Metabolomics (01.12.2015)
Published in Metabolomics (01.12.2015)
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Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes
Schmitt, Jochen, MD, MPH, Schwarz, Kristin, MSc, Baurecht, Hansjörg, MSc, Hotze, Melanie, MSc, Fölster-Holst, Regina, MD, Rodríguez, Elke, PhD, Lee, Young A.E., MD, Franke, Andre, PhD, Degenhardt, Frauke, MSc, Lieb, Wolfgang, PhD, Gieger, Christian, PhD, Kabesch, Michael, MD, Nöthen, Markus M., MD, Irvine, Alan D., MD, McLean, W.H. Irwin, PhD, Deckert, Stefanie, MPH, Stephan, Victoria, Schwarz, Peter, MD, Aringer, Martin, MD, Novak, Natalija, MD, Weidinger, Stephan, MD, MaHM
Published in Journal of allergy and clinical immunology (01.01.2016)
Published in Journal of allergy and clinical immunology (01.01.2016)
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