A Radioactivity-Based Assay for Screening Human m6A-RNA Methyltransferase, METTL3-METTL14 Complex, and Demethylase ALKBH5
Li, Fengling, Kennedy, Steven, Hajian, Taraneh, Gibson, Elisa, Seitova, Alma, Xu, Chao, Arrowsmith, Cheryl H, Vedadi, Masoud
Published in Journal of biomolecular screening (01.03.2016)
Published in Journal of biomolecular screening (01.03.2016)
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Journal Article
A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
Xu, Chenxi, Meng, Fanye, Park, Kwang-Su, Storey, Aaron J., Gong, Weida, Tsai, Yi-Hsuan, Gibson, Elisa, Byrum, Stephanie D., Li, Dongxu, Edmondson, Rick D., Mackintosh, Samuel G., Vedadi, Masoud, Cai, Ling, Tackett, Alan J., Kaniskan, H. Ümit, Jin, Jian, Wang, Gang Greg
Published in Cell chemical biology (17.03.2022)
Published in Cell chemical biology (17.03.2022)
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Journal Article
Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2
Ferreira de Freitas, Renato, Liu, Yanli, Szewczyk, Magdalena M, Mehta, Naimee, Li, Fengling, McLeod, David, Zepeda-Velázquez, Carlos, Dilworth, David, Hanley, Ronan P, Gibson, Elisa, Brown, Peter J, Al-Awar, Rima, James, Lindsey I, Arrowsmith, Cheryl H, Barsyte-Lovejoy, Dalia, Min, Jinrong, Vedadi, Masoud, Schapira, Matthieu, Allali-Hassani, Abdellah
Published in Journal of medicinal chemistry (11.02.2021)
Published in Journal of medicinal chemistry (11.02.2021)
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Journal Article
Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2
Hanley, Ronan P., Nie, David Y., Tabor, John R., Li, Fengling, Sobh, Amin, Xu, Chenxi, Barker, Natalie K., Dilworth, David, Hajian, Taraneh, Gibson, Elisa, Szewczyk, Magdalena M., Brown, Peter J., Barsyte-Lovejoy, Dalia, Herring, Laura E., Wang, Gang Greg, Licht, Jonathan D., Vedadi, Masoud, Arrowsmith, Cheryl H., James, Lindsey I.
Published in Journal of the American Chemical Society (12.04.2023)
Published in Journal of the American Chemical Society (12.04.2023)
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Journal Article
Subpocket similarity-based hit identification for challenging targets: Application to the WDR domain of LRRK2
Eguida, Merveille, Bret, Guillaume, Sindt, François, Li, Fengling, Chau, Irene, Ackloo, Suzanne, Arrowsmith, Cheryl, Bolotokova, Albina, Ghiabi, Pegah, Gibson, Elisa, Halabelian, Levon, Houliston, Scott, Harding, Rachel J, Hutchinson, Ashley, Loppnau, Peter, Perveen, Sumera, Seitova, Almagul, Zeng, Hong, Schapira, Matthieu, Rognan, Didier
Published in Journal of chemical information and modeling (25.06.2024)
Published in Journal of chemical information and modeling (25.06.2024)
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Journal Article
Subpocket Similarity-Based Hit Identification for Challenging Targets: Application to the WDR Domain of LRRK2
Eguida, Merveille, Bret, Guillaume, Sindt, François, Li, Fengling, Chau, Irene, Ackloo, Suzanne, Arrowsmith, Cheryl, Bolotokova, Albina, Ghiabi, Pegah, Gibson, Elisa, Halabelian, Levon, Houliston, Scott, Harding, Rachel J., Hutchinson, Ashley, Loppnau, Peter, Perveen, Sumera, Seitova, Almagul, Zeng, Hong, Schapira, Matthieu, Rognan, Didier
Published in Journal of chemical information and modeling (08.07.2024)
Published in Journal of chemical information and modeling (08.07.2024)
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Journal Article
A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins
Ackloo, Suzanne, Li, Fengling, Szewczyk, Magda, Seitova, Almagul, Loppnau, Peter, Zeng, Hong, Xu, Jin, Ahmad, Shabbir, Arnautova, Yelena A, Baghaie, A J, Beldar, Serap, Bolotokova, Albina, Centrella, Paolo A, Chau, Irene, Clark, Matthew A, Cuozzo, John W, Dehghani-Tafti, Saba, Disch, Jeremy S, Dong, Aiping, Dumas, Antoine, Feng, Jianwen A, Ghiabi, Pegah, Gibson, Elisa, Gilmer, Justin, Goldman, Brian, Green, Stuart R, Guié, Marie-Aude, Guilinger, John P, Harms, Nathan, Herasymenko, Oleksandra, Houliston, Scott, Hutchinson, Ashley, Kearnes, Steven, Keefe, Anthony D, Kimani, Serah W, Kramer, Trevor, Kutera, Maria, Kwak, Haejin A, Lento, Cristina, Li, Yanjun, Liu, Jenny, Loup, Joachim, Machado, Raquel A C, Mulhern, Christopher J, Perveen, Sumera, Righetto, Germanna L, Riley, Patrick, Shrestha, Suman, Sigel, Eric A, Silva, Madhushika, Sintchak, Michael D, Slakman, Belinda L, Taylor, Rhys D, Thompson, James, Torng, Wen, Underkoffler, Carl, von Rechenberg, Moritz, Walsh, Ryan T, Watson, Ian, Wilson, Derek J, Wolf, Esther, Yadav, Manisha, Yazdi, Aliakbar K, Zhang, Junyi, Zhang, Ying, Santhakumar, Vijayaratnam, Edwards, Aled M, Barsyte-Lovejoy, Dalia, Schapira, Matthieu, Brown, Peter J, Halabelian, Levon, Arrowsmith, Cheryl H
Published in Journal of medicinal chemistry (04.11.2024)
Published in Journal of medicinal chemistry (04.11.2024)
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Journal Article
PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase
Blazer, Levi L., Lima-Fernandes, Evelyne, Gibson, Elisa, Eram, Mohammad S., Loppnau, Peter, Arrowsmith, Cheryl H., Schapira, Matthieu, Vedadi, Masoud
Published in The Journal of biological chemistry (24.06.2016)
Published in The Journal of biological chemistry (24.06.2016)
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Journal Article
Identification of Inhibitors of Chikungunya virus nsP2 ATPase
Navarro, Hernan, Scott, John E, Smith, Ginger R, Ghiabi, Pegah, Gibson, Elisa, Loppnau, Peter, Harding, Rachel J, Hossain, Mohammad Anwar, Bose, Muthu Ramalingam, Pearce, Kenneth H, Merten, Eric M, Willson, Timothy M, Brown, Peter J
Published in bioRxiv (06.12.2024)
Published in bioRxiv (06.12.2024)
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Discovery of small molecule antagonists of human Retinoblastoma Binding Protein 4 (RBBP4)
Perveen, Sumera, Zepeda-Velazquez, Carlos A, Mcleod, David, Marcellus, Richard, Mohammed, Mohammed, Abbey, Megha, Ensan, Deeba, Panagopoulos, Dimitrios, Trush, Viacheslav, Gibson, Elisa, Dong, Aiping, Halabelian, Levon, Poda, Gennady, Owen, Julie, Aman, Ahmed, Kiyota, Taira, Mamai, Ahmed, Arrowsmith, Cheryl H, Brown, Peter J, Schapira, Matthieu, Al-Awar, Rima, Vedadi, Masoud
Published in bioRxiv (05.01.2022)
Published in bioRxiv (05.01.2022)
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Paper
Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2
Ferreira De Freitas, Renato, Liu, Yanli, Szewczyk, Magdalena M, Mehta, Naimee, Li, Fengling, Mcleod, David, Zepeda-Velázquez, Carlos, Dilworth, David, Hanley, Ronan P, Gibson, Elisa, Brown, Peter J, Al-Awar, Rima, Lindsey Ingerman James, Arrowsmith, Cheryl H, Barsyte-Lovejoy, Dalia, Min, Jinrong, Vedadi, Masoud, Schapira, Matthieu, Allali-Hassani, Abdellah
Published in bioRxiv (27.11.2020)
Published in bioRxiv (27.11.2020)
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Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization
Dilworth, David, Hanley, Ronan P, Ferreira De Freitas, Renato, Allali-Hassani, Abdellah, Zhou, Mengqi, Mehta, Naimee, Marunde, Matthew R, Ackloo, Suzanne, Marcon, Edyta, Li, Fengling, Chau, Irene, Bolotokova, Albina, Su, Qin, Lei, Ming, Liu, Yanli, Szewczyk, Magdalena M, Dong, Aiping, Kazemzadeh, Sina, Abramyan, Tigran, Popova, Irina K, Hall, Nathan W, Meiners, Matthew J, Cheek, Marcus A, Gibson, Elisa, Kireev, Dmitri, Greenblatt, Jack F, Michael-C Keogh, Min, Jinrong, Brown, Peter J, Vedadi, Masoud, Arrowsmith, Cheryl H, Barsyte-Lovejoy, Dalia, James, Lindsey I, Schapira, Matthieu
Published in bioRxiv (07.03.2021)
Published in bioRxiv (07.03.2021)
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