Enhanced DNA binding capacity on up-regulated epidermal wild-type p53 in vitiligo by H2O2-mediated oxidation: a possible repair mechanism for DNA damage
Salem, Mohamed M A E L, Shalbaf, Mohammad, Gibbons, Nicholas C J, Chavan, Bhaven, Thornton, J M, Schallreuter, Karin U
Published in The FASEB journal (01.11.2009)
Published in The FASEB journal (01.11.2009)
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Journal Article
Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K
Lisgarten, David R., Palmer, Rex A., Lobley, Carina M. C., Naylor, Claire E., Chowdhry, Babur Z., Al-Kurdi, Zakieh I., Badwan, Adnan A., Howlin, Brendan J., Gibbons, Nicholas C. J., Saldanha, José W., Lisgarten, John N., Basak, Ajit K.
Published in BMC chemistry (01.08.2017)
Published in BMC chemistry (01.08.2017)
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Journal Article
Oxidative Stress Via Hydrogen Peroxide Affects Proopiomelanocortin Peptides Directly in the Epidermis of Patients with Vitiligo
Spencer, Jennifer D., Gibbons, Nicholas C.J., Rokos, Hartmut, Peters, Eva M.J., Wood, John M., Schallreuter, Karin U.
Published in Journal of investigative dermatology (01.02.2007)
Published in Journal of investigative dermatology (01.02.2007)
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Journal Article
Computer Simulation of Native Epidermal Enzyme Structures in the Presence and Absence of Hydrogen Peroxide (H2O2): Potential and Pitfalls
Gibbons, Nicholas C.J., Wood, John M., Rokos, Hartmut, Schallreuter, Karin U.
Published in Journal of investigative dermatology (01.12.2006)
Published in Journal of investigative dermatology (01.12.2006)
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Journal Article
Presence of epidermal allantoin further supports oxidative stress in vitiligo
Shalbaf, Mohammad, Gibbons, Nicholas C. J., Wood, John M., Maitland, Derek J., Rokos, Hartmut, Elwary, Souna M, Marles, Lee K., Schallreuter, Karin U.
Published in Experimental dermatology (01.09.2008)
Published in Experimental dermatology (01.09.2008)
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Journal Article
Computer simulation of heterogeneous single nucleotide polymorphisms in the catalase gene indicates structural changes in the enzyme active site, NADPH-binding and tetramerization domains: a genetic predisposition for an altered catalase in patients with vitiligo?
Wood, John M., Gibbons, Nicholas C. J., Chavan, Bhaven, Schallreuter, Karin U.
Published in Experimental dermatology (01.04.2008)
Published in Experimental dermatology (01.04.2008)
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Journal Article
Methionine Sulfoxide Reductases A and B Are Deactivated by Hydrogen Peroxide (H2O2) in the Epidermis of Patients with Vitiligo
Schallreuter, Karin U., Rübsam, Katharina, Gibbons, Nicholas C.J., Maitland, Derek J., Chavan, Bhaven, Zothner, Carsten, Rokos, Hartmut, Wood, John M.
Published in Journal of investigative dermatology (01.04.2008)
Published in Journal of investigative dermatology (01.04.2008)
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Journal Article
KdPT, a tripeptide derivative of alpha-melanocyte-stimulating hormone, suppresses IL-1 beta-mediated cytokine expression and signaling in human sebocytes
Mastrofrancesco, Arianna, Kokot, Agatha, Eberle, Alex, Gibbons, Nicholas C J, Schallreuter, Karin U, Strozyk, Elwira, Picardo, Mauro, Zouboulis, Christos C, Luger, Thomas A, Böhm, Markus
Published in The Journal of immunology (1950) (01.08.2010)
Published in The Journal of immunology (1950) (01.08.2010)
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Journal Article
Perturbed 6-Tetrahydrobiopterin Recycling via Decreased Dihydropteridine Reductase in Vitiligo: More Evidence for H2O2 Stress
Hasse, Sybille, Gibbons, Nicholas C.J., Rokos, Hartmut, Marles, Lee K., Schallreuter, Karin U.
Published in Journal of investigative dermatology (01.02.2004)
Published in Journal of investigative dermatology (01.02.2004)
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Journal Article
Butyrylcholinesterase is present in the human epidermis and is regulated by H2O2: more evidence for oxidative stress in vitiligo
Schallreuter, Karin U, Gibbons, Nicholas C J, Zothner, Carsten, Elwary, Souna M, Rokos, Hartmut, Wood, John M
Published in Biochemical and biophysical research communications (27.10.2006)
Published in Biochemical and biophysical research communications (27.10.2006)
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Journal Article
Calcium-activated butyrylcholinesterase in human skin protects acetylcholinesterase against suicide inhibition by neurotoxic organophosphates
Schallreuter, Karin U., Gibbons, Nicholas C.J., Elwary, Souna M., Parkin, Susan M., Wood, John M.
Published in Biochemical and biophysical research communications (20.04.2007)
Published in Biochemical and biophysical research communications (20.04.2007)
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Journal Article
Structural and functional alterations in the β2-adrenoceptor are caused by a point mutation in patients with atopic eczema
Schallreuter, Karin U., Wei, Yuwang, Pittelkow, Mark R., Swanson, Norma N., Gibbons, Nicholas C. J., Wood, John M.
Published in Experimental dermatology (01.10.2007)
Published in Experimental dermatology (01.10.2007)
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Journal Article
Structural and functional alterations in the beta 2-adrenoceptor are caused by a point mutation in patients with atopic eczema
Schallreuter, Karin U, Wei, Yuwang, Pittelkow, Mark R, Swanson, Norma N, Gibbons, Nicholas CJ, Wood, John M
Published in Experimental dermatology (01.10.2007)
Published in Experimental dermatology (01.10.2007)
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Journal Article
Activation/deactivation of acetylcholinesterase by H2O2: more evidence for oxidative stress in vitiligo
Schallreuter, Karin U, Elwary, Souna M A, Gibbons, Nicholas C J, Rokos, Hartmut, Wood, John M
Published in Biochemical and biophysical research communications (05.03.2004)
Published in Biochemical and biophysical research communications (05.03.2004)
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Journal Article
K d PT, a Tripeptide Derivative of α-Melanocyte–Stimulating Hormone, Suppresses IL-1β–Mediated Cytokine Expression and Signaling in Human Sebocytes
Mastrofrancesco, Arianna, Kokot, Agatha, Eberle, Alex, Gibbons, Nicholas C. J., Schallreuter, Karin U., Strozyk, Elwira, Picardo, Mauro, Zouboulis, Christos C., Luger, Thomas A., Böhm, Markus
Published in The Journal of immunology (1950) (01.08.2010)
Published in The Journal of immunology (1950) (01.08.2010)
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Journal Article
Human phenylalanine hydroxylase is activated by H2O2: a novel mechanism for increasing the L-tyrosine supply for melanogenesis in melanocytes
Schallreuter, Karin U, Wazir, Umar, Kothari, Sonal, Gibbons, Nicholas C J, Moore, Jeremy, Wood, John M
Published in Biochemical and biophysical research communications (10.09.2004)
Published in Biochemical and biophysical research communications (10.09.2004)
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Journal Article
Structural and functional alterations in the beta2-adrenoceptor are caused by a point mutation in patients with atopic eczema
Schallreuter, Karin U, Wei, Yuwang, Pittelkow, Mark R, Swanson, Norma N, Gibbons, Nicholas C J, Wood, John M
Published in Experimental dermatology (01.10.2007)
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Published in Experimental dermatology (01.10.2007)
Journal Article
In situ and in vitro evidence for DCoH/HNF-1α transcription of tyrosinase in human skin melanocytes
Schallreuter, Karin U., Kothari, Sonal, Hasse, Sybille, Kauser, Söbia, Lindsey, Nigel J., Gibbons, Nicholas C.J., Hibberts, Nigel, Wood, John M.
Published in Biochemical and biophysical research communications (07.02.2003)
Published in Biochemical and biophysical research communications (07.02.2003)
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