Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis
Lelliott, Christopher J, López, Miguel, Curtis, R. Keira, Parker, Nadeene, Laudes, Matthias, Yeo, Giles, Jimenez-Liñan, Mercedes, Grosse, Johannes, Saha, Asish K, Wiggins, David, Hauton, David, Brand, Martin D, O'Rahilly, Stephen, Griffin, Julian L, Gibbons, Geoffrey F, Vidal-Puig, Antonio
Published in The FASEB journal (01.07.2005)
Published in The FASEB journal (01.07.2005)
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Journal Article
Inhibition of cholesterol absorption associated with a PPARα-dependent increase in ABC binding cassette transporter A1 in mice
Knight, Brian L., Patel, Dilip D., Humphreys, Sandy M., Wiggins, David, Gibbons, Geoffrey F.
Published in Journal of lipid research (01.11.2003)
Published in Journal of lipid research (01.11.2003)
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Journal Article
A role for PPARα in the control of SREBP activity and lipid synthesis in the liver
Knight, Brian L., Hebbachi, Abdel, Hauton, David, Brown, Anna-Marie, Wiggins, David, Patel, Dilip D., Gibbons, Geoffrey F.
Published in Biochemical journal (15.07.2005)
Published in Biochemical journal (15.07.2005)
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Peroxisome Proliferator-activated Receptor α Deficiency Abolishes the Response of Lipogenic Gene Expression to Re-feeding: RESTORATION OF THE NORMAL RESPONSE BY ACTIVATION OF LIVER X RECEPTOR α
Hebbachi, Abdel M, Knight, Brian L, Wiggins, David, Patel, Dilip D, Gibbons, Geoffrey F
Published in The Journal of biological chemistry (22.02.2008)
Published in The Journal of biological chemistry (22.02.2008)
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Journal Article
PPAR-alpha activation required for decreased glucose uptake and increased susceptibility to injury during ischemia
Panagia, Marcello, Gibbons, Geoffrey F, Radda, George K, Clarke, Kieran
Published in American journal of physiology. Heart and circulatory physiology (01.06.2005)
Published in American journal of physiology. Heart and circulatory physiology (01.06.2005)
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Mobilisation of triacylglycerol stores
Gibbons, Geoffrey F, Islam, Khwaja, Pease, Richard J
Published in BBA - Molecular and Cell Biology of Lipids (03.01.2000)
Published in BBA - Molecular and Cell Biology of Lipids (03.01.2000)
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Co-ordination of hepatic and adipose tissue lipid metabolism after oral glucose
Bülow, J, Simonsen, L, Wiggins, D, Humphreys, S M, Frayn, K N, Powell, D, Gibbons, G F
Published in Journal of lipid research (01.11.1999)
Published in Journal of lipid research (01.11.1999)
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Regulation of fatty acid and cholesterol synthesis: co-operation or competition?
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Book Review
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Glucose Phosphorylation Is Essential for the Turnover of Neutral Lipid and the Second Stage Assembly of Triacylglycerol-Rich ApoB-Containing Lipoproteins in Primary Hepatocyte Cultures
Brown, Anna-Marie, Wiggins, David, Gibbons, Geoffrey F
Published in Arteriosclerosis, thrombosis, and vascular biology (01.02.1999)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.02.1999)
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Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin
Sugden, Mary C, Bulmer, Karen, Gibbons, Geoffrey F, Knight, Brian L, Holness, Mark J
Published in Biochemical journal (01.06.2002)
Published in Biochemical journal (01.06.2002)
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Suppression of cytosolic triacylglycerol recruitment for very low density lipoprotein assembly by inactivation of microsomal triglyceride transfer protein results in a delayed removal of apoB-48 and apoB-100 from microsomal and Golgi membranes of primary rat hepatocytes
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Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice
Patel, D D, Knight, B L, Wiggins, D, Humphreys, S M, Gibbons, G F
Published in Journal of lipid research (01.03.2001)
Published in Journal of lipid research (01.03.2001)
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Journal Article
Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha)
Holness, Mark J, Bulmer, Karen, Gibbons, Geoffrey F, Sugden, Mary C
Published in Biochemical journal (15.09.2002)
Published in Biochemical journal (15.09.2002)
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Evaluation of the role of peroxisome-proliferator-activated receptor alpha in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism
Holness, Mark J, Smith, Nicholas D, Bulmer, Karen, Hopkins, Teresa, Gibbons, Geoffrey F, Sugden, Mary C
Published in Biochemical journal (15.06.2002)
Published in Biochemical journal (15.06.2002)
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