RWJ 26629, a new potassium channel opener and vascular smooth muscle relaxant: a potential antihypertensive and antianginal agent
L B Katz, E C Giardino, J J Salata, J B Moore, Jr, R Falotico
Published in The Journal of pharmacology and experimental therapeutics (01.11.1993)
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Published in The Journal of pharmacology and experimental therapeutics (01.11.1993)
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Administration of a Potent Antagonist of Protease-Activated Receptor-1 (PAR-1) Attenuates Vascular Restenosis Following Balloon Angioplasty in Rats
Andrade-Gordon, P, Derian, C K, Maryanoff, B E, Zhang, H C, Addo, M F, Cheung Wm, Damiano, B P, D'Andrea, M R, Darrow, A L, de Garavilla, L, Eckardt, A J, Giardino, E C, Haertlein, B J, McComsey, D F
Published in The Journal of pharmacology and experimental therapeutics (01.07.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.2001)
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Renal vasodilators. The role of the 4-substituent in isoquinolin-3-ol cardiovascular agents. 4-Ureido derivatives of isoquinolin-3-ol with selective renal vasodilator properties
Kanojia, Ramesh M, Lever, O. William, Press, Jeffery B, Williams, Louella, Werblood, Harvey M, Giardino, Edward C, Falotico, Robert, Tobia, Alfonso J
Published in Journal of medicinal chemistry (01.05.1989)
Published in Journal of medicinal chemistry (01.05.1989)
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A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo
de Garavilla, Lawrence, Greco, Michael N, Sukumar, Narayanasami, Chen, Zhi-Wei, Pineda, Agustin O, Mathews, F Scott, Di Cera, Enrico, Giardino, Edward C, Wells, Grace I, Haertlein, Barbara J, Kauffman, Jack A, Corcoran, Thomas W, Derian, Claudia K, Eckardt, Annette J, Damiano, Bruce P, Andrade-Gordon, Patricia, Maryanoff, Bruce E
Published in The Journal of biological chemistry (06.05.2005)
Published in The Journal of biological chemistry (06.05.2005)
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In-Depth Study of Tripeptide-Based alpha -Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S sub(1)' Subsite and Its Implications to Structure-Based Drug Design
Costanzo, MJ, Almond, HR Jr, Hecker, L R, Schott, M R, Yabut, S C, Zhang, H-C, Andrade-Gordon, P, Corcoran, T W, Giardino, E C, Kauffman, JA, Lewis, J M, de Garavilla, L, Haertlein, B J, Maryanoff, B E
Published in Journal of medicinal chemistry (24.03.2005)
Published in Journal of medicinal chemistry (24.03.2005)
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In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S-1 ' subsite and its implications to structure-based drug design
Costanzo, MJ, Almond, HR, Hecker, LR, Schott, MR, Yabut, SC, Zhang, HC, Andrade-Gordon, P, Corcoran, TW, Giardino, EC, Kauffman, JA, Lewis, JM, de Garavilla, L, Haertlein, BJ, Maryanoff, BE
Published in Journal of medicinal chemistry (24.03.2005)
Published in Journal of medicinal chemistry (24.03.2005)
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Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis
TIANBAO LU, MARKOTAN, Thomas, BONE, Roger, COPPO, Frank, TOMCZUK, Bruce, CRYSLER, Carl, EISENNAGEL, Stephen, SPURLINO, John, GREMMINGER, Lisa, SOLL, Richard M, GIARDINO, Edward C
Published in Bioorganic & medicinal chemistry letters (16.07.2004)
Published in Bioorganic & medicinal chemistry letters (16.07.2004)
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