Structures of filaments from Pick’s disease reveal a novel tau protein fold
Falcon, Benjamin, Zhang, Wenjuan, Murzin, Alexey G., Murshudov, Garib, Garringer, Holly J., Vidal, Ruben, Crowther, R. Anthony, Ghetti, Bernardino, Scheres, Sjors H. W., Goedert, Michel
Published in Nature (London) (01.09.2018)
Published in Nature (London) (01.09.2018)
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Journal Article
Structure of Tau filaments in Prion protein amyloidoses
Hallinan, Grace I., Hoq, Md Rejaul, Ghosh, Manali, Vago, Frank S., Fernandez, Anllely, Garringer, Holly J., Vidal, Ruben, Jiang, Wen, Ghetti, Bernardino
Published in Acta neuropathologica (01.08.2021)
Published in Acta neuropathologica (01.08.2021)
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Journal Article
Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
Bateman, Randall J, Xiong, Chengjie, Benzinger, Tammie L.S, Fagan, Anne M, Goate, Alison, Fox, Nick C, Marcus, Daniel S, Cairns, Nigel J, Xie, Xianyun, Blazey, Tyler M, Holtzman, David M, Santacruz, Anna, Buckles, Virginia, Oliver, Angela, Moulder, Krista, Aisen, Paul S, Ghetti, Bernardino, Klunk, William E, McDade, Eric, Martins, Ralph N, Masters, Colin L, Mayeux, Richard, Ringman, John M, Rossor, Martin N, Schofield, Peter R, Sperling, Reisa A, Salloway, Stephen, Morris, John C
Published in The New England journal of medicine (30.08.2012)
Published in The New England journal of medicine (30.08.2012)
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Journal Article
Structure-based classification of tauopathies
Shi, Yang, Zhang, Wenjuan, Yang, Yang, Murzin, Alexey G., Falcon, Benjamin, Kotecha, Abhay, van Beers, Mike, Tarutani, Airi, Kametani, Fuyuki, Garringer, Holly J., Vidal, Ruben, Hallinan, Grace I., Lashley, Tammaryn, Saito, Yuko, Murayama, Shigeo, Yoshida, Mari, Tanaka, Hidetomo, Kakita, Akiyoshi, Ikeuchi, Takeshi, Robinson, Andrew C., Mann, David M. A., Kovacs, Gabor G., Revesz, Tamas, Ghetti, Bernardino, Hasegawa, Masato, Goedert, Michel, Scheres, Sjors H. W.
Published in Nature (London) (14.10.2021)
Published in Nature (London) (14.10.2021)
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Journal Article
Astroglial tracer BU99008 detects multiple binding sites in Alzheimer’s disease brain
Kumar, Amit, Koistinen, Niina A., Malarte, Mona-Lisa, Nennesmo, Inger, Ingelsson, Martin, Ghetti, Bernardino, Lemoine, Laetitia, Nordberg, Agneta
Published in Molecular psychiatry (01.10.2021)
Published in Molecular psychiatry (01.10.2021)
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Journal Article
Brain homogenates from human tauopathies induce tau inclusions in mouse brain
Clavaguera, Florence, Akatsu, Hiroyasu, Fraser, Graham, Crowther, R. Anthony, Frank, Stephan, Hench, Jürgen, Probst, Alphonse, Winkler, David T., Reichwald, Julia, Staufenbiel, Matthias, Ghetti, Bernardino, Goedert, Michel, Tolnay, Markus
Published in Proceedings of the National Academy of Sciences - PNAS (04.06.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (04.06.2013)
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Journal Article
Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging
Ghetti, Bernardino, Oblak, Adrian L., Boeve, Bradley F., Johnson, Keith A., Dickerson, Bradford C., Goedert, Michel
Published in Neuropathology and applied neurobiology (01.02.2015)
Published in Neuropathology and applied neurobiology (01.02.2015)
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Journal Article
Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607
Shi, Yang, Murzin, Alexey G., Falcon, Benjamin, Epstein, Alexander, Machin, Jonathan, Tempest, Paul, Newell, Kathy L., Vidal, Ruben, Garringer, Holly J., Sahara, Naruhiko, Higuchi, Makoto, Ghetti, Bernardino, Jang, Ming-Kuei, Scheres, Sjors H. W., Goedert, Michel
Published in Acta neuropathologica (01.05.2021)
Published in Acta neuropathologica (01.05.2021)
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Journal Article
Age-dependent formation of TMEM106B amyloid filaments in human brains
Schweighauser, Manuel, Arseni, Diana, Bacioglu, Mehtap, Huang, Melissa, Lövestam, Sofia, Shi, Yang, Yang, Yang, Zhang, Wenjuan, Kotecha, Abhay, Garringer, Holly J., Vidal, Ruben, Hallinan, Grace I., Newell, Kathy L., Tarutani, Airi, Murayama, Shigeo, Miyazaki, Masayuki, Saito, Yuko, Yoshida, Mari, Hasegawa, Kazuko, Lashley, Tammaryn, Revesz, Tamas, Kovacs, Gabor G., van Swieten, John, Takao, Masaki, Hasegawa, Masato, Ghetti, Bernardino, Spillantini, Maria Grazia, Ryskeldi-Falcon, Benjamin, Murzin, Alexey G., Goedert, Michel, Scheres, Sjors H. W.
Published in Nature (London) (12.05.2022)
Published in Nature (London) (12.05.2022)
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Journal Article
Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease
Kraus, Allison, Saijo, Eri, Metrick, Michael A., Newell, Kathy, Sigurdson, Christina J., Zanusso, Gianluigi, Ghetti, Bernardino, Caughey, Byron
Published in Acta neuropathologica (01.04.2019)
Published in Acta neuropathologica (01.04.2019)
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Journal Article
Phenotypic diversity of genetic Creutzfeldt–Jakob disease: a histo-molecular-based classification
Baiardi, Simone, Rossi, Marcello, Mammana, Angela, Appleby, Brian S., Barria, Marcelo A., Calì, Ignazio, Gambetti, Pierluigi, Gelpi, Ellen, Giese, Armin, Ghetti, Bernardino, Herms, Jochen, Ladogana, Anna, Mikol, Jacqueline, Pal, Suvankar, Ritchie, Diane L., Ruf, Viktoria, Windl, Otto, Capellari, Sabina, Parchi, Piero
Published in Acta neuropathologica (01.10.2021)
Published in Acta neuropathologica (01.10.2021)
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Journal Article
White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network
Lee, Seonjoo, Viqar, Fawad, Zimmerman, Molly E., Narkhede, Atul, Tosto, Giuseppe, Benzinger, Tammie L.S., Marcus, Daniel S., Fagan, Anne M., Goate, Alison, Fox, Nick C., Cairns, Nigel J., Holtzman, David M., Buckles, Virginia, Ghetti, Bernardino, McDade, Eric, Martins, Ralph N., Saykin, Andrew J., Masters, Colin L., Ringman, John M., Ryan, Natalie S., Förster, Stefan, Laske, Christoph, Schofield, Peter R., Sperling, Reisa A., Salloway, Stephen, Correia, Stephen, Jack Jr, Clifford, Weiner, Michael, Bateman, Randall J., Morris, John C., Mayeux, Richard, Brickman, Adam M.
Published in Annals of neurology (01.06.2016)
Published in Annals of neurology (01.06.2016)
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Journal Article
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC
Groveman, Bradley R, Orrù, Christina D, Hughson, Andrew G, Raymond, Lynne D, Zanusso, Gianluigi, Ghetti, Bernardino, Campbell, Katrina J, Safar, Jiri, Galasko, Douglas, Caughey, Byron
Published in Acta neuropathologica communications (09.02.2018)
Published in Acta neuropathologica communications (09.02.2018)
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Journal Article
Ultrasensitive and selective detection of 3-repeat tau seeding activity in Pick disease brain and cerebrospinal fluid
Saijo, Eri, Ghetti, Bernardino, Zanusso, Gianluigi, Oblak, Adrian, Furman, Jennifer L., Diamond, Marc I., Kraus, Allison, Caughey, Byron
Published in Acta neuropathologica (01.05.2017)
Published in Acta neuropathologica (01.05.2017)
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Journal Article
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease
Rasmussen, Jay, Mahler, Jasmin, Beschorner, Natalie, Kaeser, Stephan A., Häsler, Lisa M., Baumann, Frank, Nyström, Sofie, Portelius, Erik, Blennow, Kaj, Lashley, Tammaryn, Fox, Nick C., Sepulveda-Falla, Diego, Glatzel, Markus, Oblak, Adrian L., Ghetti, Bernardino, Nilsson, K. Peter R., Hammarström, Per, Staufenbiel, Matthias, Walker, Lary C., Jucker, Mathias
Published in Proceedings of the National Academy of Sciences - PNAS (05.12.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (05.12.2017)
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Journal Article
Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons
Metrick, Michael A., Ferreira, Natalia do Carmo, Saijo, Eri, Hughson, Andrew G., Kraus, Allison, Orrú, Christina, Miller, Michael W., Zanusso, Gianluigi, Ghetti, Bernardino, Vendruscolo, Michele, Caughey, Byron
Published in Proceedings of the National Academy of Sciences - PNAS (12.11.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (12.11.2019)
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Journal Article
Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: Phase 3 study
Sabri, Osama, Sabbagh, Marwan N, Seibyl, John, Barthel, Henryk, Akatsu, Hiroyasu, Ouchi, Yasuomi, Senda, Kohei, Murayama, Shigeo, Ishii, Kenji, Takao, Masaki, Beach, Thomas G, Rowe, Christopher C, Leverenz, James B, Ghetti, Bernardino, Ironside, James W, Catafau, Ana M, Stephens, Andrew W, Mueller, Andre, Koglin, Norman, Hoffmann, Anja, Roth, Katrin, Reininger, Cornelia, Schulz-Schaeffer, Walter J
Published in Alzheimer's & dementia (01.08.2015)
Published in Alzheimer's & dementia (01.08.2015)
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Journal Article
Cryo-EM structures of prion protein filaments from Gerstmann–Sträussler–Scheinker disease
Hallinan, Grace I., Ozcan, Kadir A., Hoq, Md Rejaul, Cracco, Laura, Vago, Frank S., Bharath, Sakshibeedu R., Li, Daoyi, Jacobsen, Max, Doud, Emma H., Mosley, Amber L., Fernandez, Anllely, Garringer, Holly J., Jiang, Wen, Ghetti, Bernardino, Vidal, Ruben
Published in Acta neuropathologica (01.09.2022)
Published in Acta neuropathologica (01.09.2022)
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Journal Article
Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains
Orrú, Christina D, Groveman, Bradley R, Raymond, Lynne D, Hughson, Andrew G, Nonno, Romolo, Zou, Wenquan, Ghetti, Bernardino, Gambetti, Pierluigi, Caughey, Byron
Published in PLoS pathogens (01.06.2015)
Published in PLoS pathogens (01.06.2015)
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Journal Article
Dominantly inherited prion protein cerebral amyloidoses – a modern view of Gerstmann–Sträussler–Scheinker
Ghetti, Bernardino, Piccardo, Pedro, Zanusso, Gianluigi
Published in Handbook of Clinical Neurology (2018)
Published in Handbook of Clinical Neurology (2018)
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Book Chapter
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