RVX-208, an inducer of ApoA-I in humans, is a BET bromodomain antagonist
McLure, Kevin G, Gesner, Emily M, Tsujikawa, Laura, Kharenko, Olesya A, Attwell, Sarah, Campeau, Eric, Wasiak, Sylwia, Stein, Adam, White, Andre, Fontano, Eric, Suto, Robert K, Wong, Norman C W, Wagner, Gregory S, Hansen, Henrik C, Young, Peter R
Published in PloS one (31.12.2013)
Published in PloS one (31.12.2013)
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Journal Article
BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma
Bhadury, Joydeep, Nilsson, Lisa M, Muralidharan, Somsundar Veppil, Green, Lydia C, Li, Zhoulei, Gesner, Emily M, Hansen, Henrik C, Keller, Ulrich B, McLure, Kevin G, Nilsson, Jonas A
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.2014)
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Journal Article
RVX-297- a novel BD2 selective inhibitor of BET bromodomains
Kharenko, Olesya A., Gesner, Emily M., Patel, Reena G., Norek, Karen, White, Andre, Fontano, Eric, Suto, Robert K., Young, Peter R., McLure, Kevin G., Hansen, Henrik C.
Published in Biochemical and biophysical research communications (12.08.2016)
Published in Biochemical and biophysical research communications (12.08.2016)
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Journal Article
BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Kim, Dae-Hwan, Sun, Duanchen, Storck, William K, Welker Leng, Katherine, Jenkins, Chelsea, Coleman, Daniel J, Sampson, David, Guan, Xiangnan, Kumaraswamy, Anbarasu, Rodansky, Eva S, Urrutia, Joshua A, Schwartzman, Jacob A, Zhang, Chao, Beltran, Himisha, Labrecque, Mark P, Morrissey, Colm, Lucas, Jared M, Coleman, Ilsa M, Nelson, Peter S, Corey, Eva, Handelman, Samuel K, Sexton, Jonathan Z, Aggarwal, Rahul, Abida, Wassim, Feng, Felix Y, Small, Eric J, Spratt, Daniel E, Bankhead, 3rd, Armand, Rao, Arvind, Gesner, Emily M, Attwell, Sarah, Lakhotia, Sanjay, Campeau, Eric, Yates, Joel A, Xia, Zheng, Alumkal, Joshi J
Published in Clinical cancer research (01.09.2021)
Published in Clinical cancer research (01.09.2021)
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Journal Article
Role of pri-miRNA tertiary structure in miR-17~92 miRNA biogenesis
Chaulk, Steven G, Thede, Gina L., Kent, Oliver A., Xu, Zhizhong, Gesner, Emily, Veldhoen, Richard A., Khanna, Suneil K., Goping, Ing Swie, MacMillan, Andrew M., Mendell, Joshua T., Young, Howard, Fahlman, Richard P., Glover, J.N. Mark
Published in RNA biology (01.11.2011)
Published in RNA biology (01.11.2011)
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Journal Article
Cas5d processes pre-crRNA and is a member of a larger family of CRISPR RNA endonucleases
Garside, Erin L, Schellenberg, Matthew J, Gesner, Emily M, Bonanno, Jeffrey B, Sauder, J Michael, Burley, Stephen K, Almo, Steven C, Mehta, Garima, MacMillan, Andrew M
Published in RNA (Cambridge) (01.11.2012)
Published in RNA (Cambridge) (01.11.2012)
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Journal Article
Nursing Documentation Variation Across Different Medical Facilities Within an Integrated Healthcare System
Kang, Min-Jeoung, Rossetti, Sarah Collins, Knaplund, Christopher, Chang, Frank Y, Schnock, Kumiko O, Whalen, Kimberly, Gesner, Emily J, Garcia, Jose P, Cato, Kenrick D, Dykes, Patricia C
Published in Computers, informatics, nursing (01.12.2021)
Published in Computers, informatics, nursing (01.12.2021)
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Journal Article
Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design
Duffy, Bryan C., Liu, Shuang, Martin, Gregory S., Wang, Ruifang, Hsia, Ming Min, Zhao, He, Guo, Cheng, Ellis, Michael, Quinn, John F., Kharenko, Olesya A., Norek, Karen, Gesner, Emily M., Young, Peter R., McLure, Kevin G., Wagner, Gregory S., Lakshminarasimhan, Damodharan, White, Andre, Suto, Robert K., Hansen, Henrik C., Kitchen, Douglas B.
Published in Bioorganic & medicinal chemistry letters (15.07.2015)
Published in Bioorganic & medicinal chemistry letters (15.07.2015)
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Journal Article
FRET Analysis of in Vivo Dimerization by RNA-editing Enzymes
Chilibeck, Kaari A., Wu, Tao, Liang, Chao, Schellenberg, Matthew J., Gesner, Emily M., Lynch, Jeffrey M., MacMillan, Andrew M.
Published in The Journal of biological chemistry (16.06.2006)
Published in The Journal of biological chemistry (16.06.2006)
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Journal Article
A Decade of Experience in Creating and Maintaining Data Elements for Structured Clinical Documentation in EHRs
Zhou, Li, Collins, Sarah, Morgan, Stephen J, Zafar, Neelam, Gesner, Emily J, Fehrenbach, Martin, Rocha, Roberto A
Published in AMIA ... Annual Symposium proceedings (2016)
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Published in AMIA ... Annual Symposium proceedings (2016)
Journal Article
Documentation Burden in Nursing and Its Role in Clinician Burnout Syndrome
Gesner, Emily, Dykes, Patricia C., Zhang, Lingling, Gazarian, Priscilla
Published in Applied clinical informatics (01.10.2022)
Published in Applied clinical informatics (01.10.2022)
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Journal Article
Pain Documentation: Validation of a Reference Model
Gesner, Emily, Collins, Sarah A, Rocha, Roberto
Published in Studies in health technology and informatics (2015)
Published in Studies in health technology and informatics (2015)
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Journal Article
Abstract C86: The clinical candidate ZEN-3694, a novel BET bromodomain inhibitor, is efficacious in the treatment of a variety of solid tumor and hematological malignancies, alone or in combination with several standard of care and targeted therapies
Attwell, Sarah, Campeau, Eric, Jahagirdar, Ravi, Kharenko, Olesya, Norek, Karen, Tsujikawa, Laura, Calosing, Cyrus, Patel, Reena, Gesner, Emily, Lakhotia, Sanjay, Hansen, Henrik
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Journal Article
Abstract LB-207: Preclinical characterization of ZEN-3694, a novel BET bromodomain inhibitor entering phase I studies for metastatic castration-resistant prostate cancer (mCRPC)
Attwell, Sarah, Jahagirdar, Ravi, Norek, Karen, Calosing, Cyrus, Tsujikawa, Laura, Kharenko, Olesya A., Patel, Reena G., Gesner, Emily M., Corey, Eva, Nguyen, Holly M., Lakhotia, Sanjay, Hansen, Henrik C., Campeau, Eric
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 5495: BET bromodomain inhibitors abrogate cell cycle progression and induces apoptosis in Myc-induced mouse lymphoma cells without affecting MYC transcription
Bhadury, Joydeep, Nilsson, Lisa M., Green, Lydia, Li, Zhoulei, Gesner, Emily M., Muralidharan, Somsundar Veppil, Hansen, Henrik C., Keller, Ulrich B., Mclure, Kevin G., Nilsson, Jonas A.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine lymphoma
Bhadury, Joydeep, Nilsson, Lisa M., Muralidharan, Somsundar Veppil, Green, Lydia C., Li, Zhoulei, Gesner, Emily M., Hansen, Henrik C., Keller, Ulrich B., McLure, Kevin G., Nilsson, Jonas A.
Published in Proceedings of the National Academy of Sciences - PNAS (01.07.2014)
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Published in Proceedings of the National Academy of Sciences - PNAS (01.07.2014)
Journal Article