IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
Nold-Petry, Claudia A, Lo, Camden Y, Rudloff, Ina, Elgass, Kirstin D, Li, Suzhao, Gantier, Michael P, Lotz-Havla, Amelie S, Gersting, Søren W, Cho, Steven X, Lao, Jason C, Ellisdon, Andrew M, Rotter, Björn, Azam, Tania, Mangan, Niamh E, Rossello, Fernando J, Whisstock, James C, Bufler, Philip, Garlanda, Cecilia, Mantovani, Alberto, Dinarello, Charles A, Nold, Marcel F
Published in Nature immunology (01.04.2015)
Published in Nature immunology (01.04.2015)
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Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production
Roth, Susanne, Rottach, Andrea, Lotz-Havla, Amelie S, Laux, Verena, Muschaweckh, Andreas, Gersting, Søren W, Muntau, Ania C, Hopfner, Karl-Peter, Jin, Lei, Vanness, Katelynd, Petrini, John H J, Drexler, Ingo, Leonhardt, Heinrich, Ruland, Jürgen
Published in Nature immunology (01.06.2014)
Published in Nature immunology (01.06.2014)
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Innovative strategies to treat protein misfolding in inborn errors of metabolism: pharmacological chaperones and proteostasis regulators
Muntau, Ania C., Leandro, João, Staudigl, Michael, Mayer, Felix, Gersting, Søren W.
Published in Journal of inherited metabolic disease (01.07.2014)
Published in Journal of inherited metabolic disease (01.07.2014)
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Journal Article
Conference Proceeding
Glutaryl-CoA Dehydrogenase Misfolding in Glutaric Acidemia Type 1
Barroso, Madalena, Gertzen, Marcus, Puchwein-Schwepcke, Alexandra F, Preisler, Heike, Sturm, Andreas, Reiss, Dunja D, Danecka, Marta K, Muntau, Ania C, Gersting, Søren W
Published in International journal of molecular sciences (01.09.2023)
Published in International journal of molecular sciences (01.09.2023)
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Journal Article
Use of the Novel Site-Directed Enzyme Enhancement Therapy (SEE-Tx) Drug Discovery Platform to Identify Pharmacological Chaperones for Glutaric Acidemia Type 1
Barroso, Madalena, Puchwein-Schwepcke, Alexandra, Buettner, Lars, Goebel, Ingrid, Küchler, Katrin, Muntau, Ania C., Delgado, Aida, Garcia-Collazo, Ana M., Martinell, Marc, Barril, Xavier, Cubero, Elena, Gersting, Søren W.
Published in Journal of medicinal chemistry (10.10.2024)
Published in Journal of medicinal chemistry (10.10.2024)
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Journal Article
Inborn errors of metabolism and the human interactome: a systems medicine approach
Woidy, Mathias, Muntau, Ania C., Gersting, Søren W.
Published in Journal of inherited metabolic disease (01.05.2018)
Published in Journal of inherited metabolic disease (01.05.2018)
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Journal Article
Secondary BH4 deficiency links protein homeostasis to regulation of phenylalanine metabolism
Eichinger, Anna, Danecka, Marta K, Möglich, Tamara, Borsch, Julia, Woidy, Mathias, Büttner, Lars, Muntau, Ania C, Gersting, Søren W
Published in Human molecular genetics (15.05.2018)
Published in Human molecular genetics (15.05.2018)
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Journal Article
iBRET Screen of the ABCD1 Peroxisomal Network and Mutation-Induced Network Perturbations
Lotz-Havla, Amelie S, Woidy, Mathias, Guder, Philipp, Friedel, Caroline C, Klingbeil, Julian M, Bulau, Ana-Maria, Schultze, Anja, Dahmen, Ilona, Noll-Puchta, Heidi, Kemp, Stephan, Erdmann, Ralf, Zimmer, Ralf, Muntau, Ania C, Gersting, Søren W
Published in Journal of proteome research (03.09.2021)
Published in Journal of proteome research (03.09.2021)
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Journal Article
Mapping the functional landscape of frequent phenylalanine hydroxylase (PAH) genotypes promotes personalised medicine in phenylketonuria
Danecka, Marta K, Woidy, Mathias, Zschocke, Johannes, Feillet, François, Muntau, Ania C, Gersting, Søren W
Published in Journal of medical genetics (01.03.2015)
Published in Journal of medical genetics (01.03.2015)
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Specific CD4+ T Cell Responses to Ancestral SARS-CoV-2 in Children Increase With Age and Show Cross-Reactivity to Beta Variant
Paul, Kevin, Sibbertsen, Freya, Weiskopf, Daniela, Lütgehetmann, Marc, Barroso, Madalena, Danecka, Marta K, Glau, Laura, Hecher, Laura, Hermann, Katharina, Kohl, Aloisa, Oh, Jun, Schulze Zur Wiesch, Julian, Sette, Alessandro, Tolosa, Eva, Vettorazzi, Eik, Woidy, Mathias, Zapf, Antonia, Zazara, Dimitra E, Mir, Thomas S, Muntau, Ania C, Gersting, Søren W, Dunay, Gabor A
Published in Frontiers in immunology (15.07.2022)
Published in Frontiers in immunology (15.07.2022)
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Phenotypic analysis of the pediatric immune response to SARS‐CoV‐2 by flow cytometry
Sibbertsen, Freya, Glau, Laura, Paul, Kevin, Mir, Thomas S., Gersting, Søren W., Tolosa, Eva, Dunay, Gabor A.
Published in Cytometry. Part A (01.03.2022)
Published in Cytometry. Part A (01.03.2022)
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Reduced Humoral and Cellular Immune Response to Primary COVID-19 mRNA Vaccination in Kidney Transplanted Children Aged 5-11 Years
Lalia, Jasmin K, Schild, Raphael, Lütgehetmann, Marc, Dunay, Gabor A, Kallinich, Tilmann, Kobbe, Robin, Massoud, Mona, Oh, Jun, Pietzsch, Leonora, Schulze-Sturm, Ulf, Schuetz, Catharina, Sibbertsen, Freya, Speth, Fabian, Thieme, Sebastian, Witkowski, Mario, Berner, Reinhard, Muntau, Ania C, Gersting, Søren W, Toepfner, Nicole, Pagel, Julia, Paul, Kevin
Published in Viruses (01.07.2023)
Published in Viruses (01.07.2023)
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Journal Article
Isoform-specific domain organization determines conformation and function of the peroxisomal biogenesis factor PEX26
Guder, Philipp, Lotz-Havla, Amelie S., Woidy, Mathias, Reiß, Dunja D., Danecka, Marta K., Schatz, Ulrich A., Becker, Marc, Ensenauer, Regina, Pagel, Philipp, Büttner, Lars, Muntau, Ania C., Gersting, Søren W.
Published in Biochimica et biophysica acta. Molecular cell research (01.03.2019)
Published in Biochimica et biophysica acta. Molecular cell research (01.03.2019)
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Journal Article
Edgetic Perturbations Contribute to Phenotypic Variability in PEX26 Deficiency
Lotz-Havla, Amelie S., Woidy, Mathias, Guder, Philipp, Schmiesing, Jessica, Erdmann, Ralf, Waterham, Hans R., Muntau, Ania C., Gersting, Søren W.
Published in Frontiers in genetics (04.11.2021)
Published in Frontiers in genetics (04.11.2021)
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Journal Article
Disease-causing mutations affecting surface residues of mitochondrial glutaryl-CoA dehydrogenase impair stability, heteromeric complex formation and mitochondria architecture
Schmiesing, Jessica, Lohmöller, Benjamin, Schweizer, Michaela, Tidow, Henning, Gersting, Søren W, Muntau, Ania C, Braulke, Thomas, Mühlhausen, Chris
Published in Human molecular genetics (01.02.2017)
Published in Human molecular genetics (01.02.2017)
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Journal Article
Loss of Function in Phenylketonuria Is Caused by Impaired Molecular Motions and Conformational Instability
Gersting, Søren W., Kemter, Kristina F., Staudigl, Michael, Messing, Dunja D., Danecka, Marta K., Lagler, Florian B., Sommerhoff, Christian P., Roscher, Adelbert A., Muntau, Ania C.
Published in American journal of human genetics (01.07.2008)
Published in American journal of human genetics (01.07.2008)
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Journal Article
The domain-specific and temperature-dependent protein misfolding phenotype of variant medium-chain acyl-CoA dehydrogenase
Jank, Johanna M, Maier, Esther M, Reiβ, Dunja D, Haslbeck, Martin, Kemter, Kristina F, Truger, Marietta S, Sommerhoff, Christian P, Ferdinandusse, Sacha, Wanders, Ronald J, Gersting, Søren W, Muntau, Ania C
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Journal Article
Identification of a New Fatty Acid Synthesis-Transport Machinery at the Peroxisomal Membrane
Hillebrand, Merle, Gersting, Søren W., Lotz-Havla, Amelie S., Schäfer, Annika, Rosewich, Hendrik, Valerius, Oliver, Muntau, Ania C., Gärtner, Jutta
Published in The Journal of biological chemistry (02.01.2012)
Published in The Journal of biological chemistry (02.01.2012)
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