Potential mechanisms and implications for the formation of tau oligomeric strains
Gerson, Julia E., Mudher, Amrit, Kayed, Rakez
Published in Critical reviews in biochemistry and molecular biology (01.11.2016)
Published in Critical reviews in biochemistry and molecular biology (01.11.2016)
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Journal Article
α-Synuclein Oligomers Induce a Unique Toxic Tau Strain
Castillo-Carranza, Diana L., Guerrero-Muñoz, Marcos J., Sengupta, Urmi, Gerson, Julia E., Kayed, Rakez
Published in Biological psychiatry (1969) (01.10.2018)
Published in Biological psychiatry (1969) (01.10.2018)
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Journal Article
Pathological Interface Between Oligomeric Alpha-Synuclein and Tau in Synucleinopathies
Sengupta, Urmi, Guerrero-Muñoz, Marcos J, Castillo-Carranza, Diana L, Lasagna-Reeves, Cristian A, Gerson, Julia E, Paulucci-Holthauzen, Adriana A, Krishnamurthy, Shashirekha, Farhed, Malika, Jackson, George R, Kayed, Rakez
Published in Biological psychiatry (1969) (15.11.2015)
Published in Biological psychiatry (1969) (15.11.2015)
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Journal Article
Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases
Nilson, Ashley N, English, Kelsey C, Gerson, Julia E, Barton Whittle, T, Nicolas Crain, C, Xue, Judy, Sengupta, Urmi, Castillo-Carranza, Diana L, Zhang, Wenbo, Gupta, Praveena, Kayed, Rakez
Published in Journal of Alzheimer's disease (01.01.2017)
Published in Journal of Alzheimer's disease (01.01.2017)
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Journal Article
Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles
Castillo-Carranza, Diana L, Sengupta, Urmi, Guerrero-Muñoz, Marcos J, Lasagna-Reeves, Cristian A, Gerson, Julia E, Singh, Gurpreet, Estes, D Mark, Barrett, Alan D T, Dineley, Kelly T, Jackson, George R, Kayed, Rakez
Published in The Journal of neuroscience (19.03.2014)
Published in The Journal of neuroscience (19.03.2014)
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Journal Article
Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy
Gerson, Julia E, Farmer, Kathleen M, Henson, Natalie, Castillo-Carranza, Diana L, Carretero Murillo, Mariana, Sengupta, Urmi, Barrett, Alan, Kayed, Rakez
Published in Molecular neurodegeneration (15.03.2018)
Published in Molecular neurodegeneration (15.03.2018)
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Journal Article
Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly
Sharkey, Lisa M., Safren, Nathaniel, Pithadia, Amit S., Gerson, Julia E., Dulchavsky, Mark, Fischer, Svetlana, Patel, Ronak, Lantis, Gabrielle, Ashraf, Naila, Kim, John H., Meliki, Alia, Minakawa, Eiko N., Barmada, Sami J., Ivanova, Magdalena I., Paulson, Henry L.
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2018)
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Journal Article
Specific Targeting of Tau Oligomers in Htau Mice Prevents Cognitive Impairment and Tau Toxicity Following Injection with Brain-Derived Tau Oligomeric Seeds
Castillo-Carranza, Diana L., Gerson, Julia E., Sengupta, Urmi, Guerrero-Muñoz, Marcos J., Lasagna-Reeves, Cristian A., Kayed, Rakez
Published in Journal of Alzheimer's disease (01.01.2014)
Published in Journal of Alzheimer's disease (01.01.2014)
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Journal Article
Tau Oligomers Derived from Traumatic Brain Injury Cause Cognitive Impairment and Accelerate Onset of Pathology in Htau Mice
Gerson, Julia, Castillo-Carranza, Diana L, Sengupta, Urmi, Bodani, Riddhi, Prough, Donald S, DeWitt, Douglas S, Hawkins, Bridget E, Kayed, Rakez
Published in Journal of neurotrauma (15.11.2016)
Published in Journal of neurotrauma (15.11.2016)
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Journal Article
Modeling UBQLN2-mediated neurodegenerative disease in mice: Shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered proteostasis pathways, and selective cytotoxicity
Sharkey, Lisa M., Sandoval-Pistorius, Stephanie S., Moore, Shannon J., Gerson, Julia E., Komlo, Robert, Fischer, Svetlana, Negron-Rios, Keyshla Y., Crowley, Emily V., Padron, Francisco, Patel, Ronak, Murphy, Geoffrey G., Paulson, Henry L.
Published in Neurobiology of disease (01.09.2020)
Published in Neurobiology of disease (01.09.2020)
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Journal Article
Ubiquilin-2 regulates pathological alpha-synuclein
Sandoval-Pistorius, Stephanie S., Gerson, Julia E., Liggans, Nyjerus, Ryou, Jaimie H., Oak, Kulin, Li, Xingli, Negron-Rios, Keyshla Y., Fischer, Svetlana, Barsh, Henry, Crowley, Emily V., Skinner, Mary E., Sharkey, Lisa M., Barmada, Sami J., Paulson, Henry L.
Published in Scientific reports (06.01.2023)
Published in Scientific reports (06.01.2023)
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Journal Article
Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy
Gerson, Julia E, Sandoval-Pistorius, Stephanie, Welday, Jacqueline P, Rodriguez, Aleija, Gregory, Jordan D, Liggans, Nyjerus, Schache, Kylie, Li, Xingli, Trzeciakiewicz, Hanna, Barmada, Sami, Sharkey, Lisa M, Paulson, Henry L
Published in The Journal of neuroscience (02.03.2022)
Published in The Journal of neuroscience (02.03.2022)
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Journal Article
Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins
Gerson, Julia E., Linton, Hunter, Xing, Jiazheng, Sutter, Alexandra B., Kakos, Fayth S., Ryou, Jaimie, Liggans, Nyjerus, Sharkey, Lisa M., Safren, Nathaniel, Paulson, Henry L., Ivanova, Magdalena I.
Published in Scientific reports (11.01.2021)
Published in Scientific reports (11.01.2021)
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Journal Article
AAV2-mediated GRP78 Transfer Alleviates Retinal Neuronal Injury by Downregulating ER Stress and Tau Oligomer Formation
Ha, Yonju, Liu, Wei, Liu, Hua, Zhu, Shuang, Xia, Fan, Gerson, Julia E, Azhar, Nisha A, Tilton, Ronald G, Motamedi, Massoud, Kayed, Rakez, Zhang, Wenbo
Published in Investigative ophthalmology & visual science (01.09.2018)
Published in Investigative ophthalmology & visual science (01.09.2018)
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Journal Article
Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer's Disease and Related Tauopathies
Castillo-Carranza, Diana L, Nilson, Ashley N, Van Skike, Candice E, Jahrling, Jordan B, Patel, Kishan, Garach, Prajesh, Gerson, Julia E, Sengupta, Urmi, Abisambra, Jose, Nelson, Peter, Troncoso, Juan, Ungvari, Zoltan, Galvan, Veronica, Kayed, Rakez
Published in Aging and disease (01.06.2017)
Published in Aging and disease (01.06.2017)
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