The next generation of CRISPR-Cas technologies and applications
Pickar-Oliver, Adrian, Gersbach, Charles A
Published in Nature reviews. Molecular cell biology (01.08.2019)
Published in Nature reviews. Molecular cell biology (01.08.2019)
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Journal Article
Editing the Epigenome: Reshaping the Genomic Landscape
Holtzman, Liad, Gersbach, Charles A
Published in Annual review of genomics and human genetics (31.08.2018)
Published in Annual review of genomics and human genetics (31.08.2018)
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Journal Article
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
Gaj, Thomas, Gersbach, Charles A, Barbas, Carlos F
Published in Trends in biotechnology (Regular ed.) (01.07.2013)
Published in Trends in biotechnology (Regular ed.) (01.07.2013)
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Journal Article
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
Thakore, Pratiksha I, D'Ippolito, Anthony M, Song, Lingyun, Safi, Alexias, Shivakumar, Nishkala K, Kabadi, Ami M, Reddy, Timothy E, Crawford, Gregory E, Gersbach, Charles A
Published in Nature methods (01.12.2015)
Published in Nature methods (01.12.2015)
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Journal Article
Increasing the specificity of CRISPR systems with engineered RNA secondary structures
Kocak, D Dewran, Josephs, Eric A, Bhandarkar, Vidit, Adkar, Shaunak S, Kwon, Jennifer B, Gersbach, Charles A
Published in Nature biotechnology (01.06.2019)
Published in Nature biotechnology (01.06.2019)
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Journal Article
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy
Nelson, Christopher E., Hakim, Chady H., Ousterout, David G., Thakore, Pratiksha I., Moreb, Eirik A., Rivera, Ruth M. Castellanos, Madhavan, Sarina, Pan, Xiufang, Ran, F. Ann, Yan, Winston X., Asokan, Aravind, Zhang, Feng, Duan, Dongsheng, Gersbach, Charles A.
Published in Science (American Association for the Advancement of Science) (22.01.2016)
Published in Science (American Association for the Advancement of Science) (22.01.2016)
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Journal Article
Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector
Kabadi, Ami M, Ousterout, David G, Hilton, Isaac B, Gersbach, Charles A
Published in Nucleic acids research (29.10.2014)
Published in Nucleic acids research (29.10.2014)
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Journal Article
Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells
Black, Joshua B., Adler, Andrew F., Wang, Hong-Gang, D’Ippolito, Anthony M., Hutchinson, Hunter A., Reddy, Timothy E., Pitt, Geoffrey S., Leong, Kam W., Gersbach, Charles A.
Published in Cell stem cell (01.09.2016)
Published in Cell stem cell (01.09.2016)
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Journal Article
Epigenome editing technologies for discovery and medicine
McCutcheon, Sean R, Rohm, Dahlia, Iglesias, Nahid, Gersbach, Charles A
Published in Nature biotechnology (01.08.2024)
Published in Nature biotechnology (01.08.2024)
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Journal Article
Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy
Ousterout, David G, Kabadi, Ami M, Thakore, Pratiksha I, Majoros, William H, Reddy, Timothy E, Gersbach, Charles A
Published in Nature communications (18.02.2015)
Published in Nature communications (18.02.2015)
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Journal Article
RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors
Thakore, Pratiksha I, Kwon, Jennifer B, Nelson, Christopher E, Rouse, Douglas C, Gemberling, Matthew P, Oliver, Matthew L, Gersbach, Charles A
Published in Nature communications (26.04.2018)
Published in Nature communications (26.04.2018)
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Journal Article
Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy
Nelson, Christopher E, Wu, Yaoying, Gemberling, Matthew P, Oliver, Matthew L, Waller, Matthew A, Bohning, Joel D, Robinson-Hamm, Jacqueline N, Bulaklak, Karen, Castellanos Rivera, Ruth M, Collier, Joel H, Asokan, Aravind, Gersbach, Charles A
Published in Nature medicine (01.03.2019)
Published in Nature medicine (01.03.2019)
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Journal Article