Presence of mutant p53 increases stem cell frequency and is associated with reduced binding to classic TP53 binding sites in cell lines and primary AMLs
Gerritsen, Mylène, Hilgendorf, Susan, Yi, Guoqiang, Wierenga, Albertus T.J., Schuringa, Jan-Jacob, Martens, Joost H.A., Vellenga, Edo
Published in Experimental hematology (01.06.2022)
Published in Experimental hematology (01.06.2022)
Get full text
Journal Article
Tumor suppressor BTG1 limits activation of BCL6 expression downstream of ETV6-RUNX1
Tijchon, Esther, van Emst, Liesbeth, Yuniati, Laurensia, van Ingen Schenau, Dorette, Gerritsen, Mylène, van der Meer, Laurens T., Williams, Owen, Hoogerbrugge, Peter M., Scheijen, Blanca, van Leeuwen, Frank N.
Published in Experimental hematology (01.04.2018)
Published in Experimental hematology (01.04.2018)
Get full text
Journal Article
P455: RUNX1 DIRECTLY BINDS AND REGULATES THE TCF4 PROMOTER
Gerritsen, Mylene, In‘t Hout, Florentien E.M., G.H.J.N. Knops, Ruth, Van Der Reijden, Bert A., Martens, Joost H.A., H Jansen, Joop
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
Get full text
Journal Article
Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern
Berger, Gerbrig, Gerritsen, Mylene, Yi, Guoqiang, Koorenhof-Scheele, Theresia N., Kroeze, Leonie I., Stevens-Kroef, Marian, Yoshida, Kenichi, Shiraishi, Yuichi, van den Berg, Eva, Schepers, Hein, Huls, Geert, Mulder, André B., Ogawa, Seishi, Martens, Joost H.A., Jansen, Joop H., Vellenga, Edo
Published in Blood advances (22.10.2019)
Published in Blood advances (22.10.2019)
Get full text
Journal Article
CD34 + acute myeloid leukemia cells with low levels of reactive oxygen species show increased expression of stemness genes and can be targeted by the BCL2 inhibitor venetoclax
Mattes, Katharina, Gerritsen, Mylène, Folkerts, Hendrik, Geugien, Marjan, van den Heuvel, Fiona A, Svendsen, Arthur Flohr, Yi, Guoqiang, Martens, Joost H A, Vellenga, Edo
Published in Haematologica (Roma) (01.08.2020)
Published in Haematologica (Roma) (01.08.2020)
Get full text
Journal Article
Transcription factor 4 ( TCF4 ) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia
In't Hout, Florentien E M, Gerritsen, Mylène, Bullinger, Lars, Van der Reijden, Bert A, Huls, Gerwin, Vellenga, Edo, Jansen, Joop H
Published in Haematologica (Roma) (01.09.2020)
Published in Haematologica (Roma) (01.09.2020)
Get full text
Journal Article
RUNX1 Mutations Lead to a Myeloid Differentiation Block in Association with Enhanced Proliferation By Altering the RUNX1 Transcriptional Program
Gerritsen, Mylène, Tijchon, Esther, Yi, Guoqiang, Kuster, Jorren, Schuringa, Jan Jacob, Martens, Joost H.A., Vellenga, Edo
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
Get full text
Journal Article
RUNX1 Mutations Cause a Myeloid Differentiation Block Leading to the Formation of a Long Term Expanding CD34+/CD33+/CD45RA+/CD123+ Cell Population
Gerritsen, Myléne, Tijchon, Esther, Mandoli, Amit, Martens, Joost H.A., Schuringa, Jan Jacob, Vellenga, Edo
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
RUNX1 mutations enhance self-renewal and block granulocytic differentiation in human in vitro models and primary AMLs
Gerritsen, Mylène, Yi, Guoqiang, Tijchon, Esther, Kuster, Jorren, Schuringa, Jan Jacob, Martens, Joost H.A., Vellenga, Edo
Published in Blood advances (12.02.2019)
Published in Blood advances (12.02.2019)
Get full text
Journal Article
Transcription factor 4 (TCF4) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia
In 't Hout, Florentien E M, Gerritsen, Mylène, Bullinger, Lars, van der Reijden, Bert A, Huls, Gerwin, Vellenga, Edo, Jansen, Joop H
Published in Haematologica (Roma) (19.12.2019)
Get full text
Published in Haematologica (Roma) (19.12.2019)
Journal Article