Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302)
Geretti, Elena, Leonard, Shannon Curtis, Dumont, Nancy, Lee, Helen, Zheng, Jinzi, De Souza, Raquel, Gaddy, Daniel F, Espelin, Christopher W, Jaffray, David A, Moyo, Victor, Nielsen, Ulrik B, Wickham, Thomas J, Hendriks, Bart S
Published in Molecular cancer therapeutics (01.09.2015)
Published in Molecular cancer therapeutics (01.09.2015)
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Journal Article
A mutated soluble neuropilin-2 B domain antagonizes vascular endothelial growth factor bioactivity and inhibits tumor progression
Geretti, Elena, van Meeteren, Laurens A, Shimizu, Akio, Dudley, Andrew C, Claesson-Welsh, Lena, Klagsbrun, Michael
Published in Molecular cancer research (01.08.2010)
Published in Molecular cancer research (01.08.2010)
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Journal Article
64Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response in Patients with Metastatic Breast Cancer
Lee, Helen, Shields, Anthony F., Siegel, Barry A., Miller, Kathy D., Krop, Ian, Ma, Cynthia X., LoRusso, Patricia M., Munster, Pamela N., Campbell, Karen, Gaddy, Daniel F., Leonard, Shannon C., Geretti, Elena, Blocker, Stephanie J., Kirpotin, Dmitri B., Moyo, Victor, Wickham, Thomas J., Hendriks, Bart S.
Published in Clinical cancer research (01.08.2017)
Published in Clinical cancer research (01.08.2017)
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Journal Article
Designing CXCL8-based decoy proteins with strong anti-inflammatory activity in vivo
Falsone, Angelika, Wabitsch, Veronica, Geretti, Elena, Potzinger, Heide, Gerlza, Tanja, Robinson, James, Adage, Tiziana, Teixeira, Mauro M, Kungl, Andreas J
Published in Bioscience reports (17.09.2013)
Published in Bioscience reports (17.09.2013)
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Journal Article
VEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells
Yoshida, Ayumi, Shimizu, Akio, Asano, Hirotsugu, Kadonosono, Tetsuya, Kondoh, Shinae Kizaka, Geretti, Elena, Mammoto, Akiko, Klagsbrun, Michael, Seo, Misuzu Kurokawa
Published in Biology open (24.07.2015)
Published in Biology open (24.07.2015)
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Journal Article
801 PRIME™ IL-15 (RPTR-147): Preliminary clinical results and biomarker analysis from a first-in-human Phase 1 study of IL-15 loaded peripherally-derived autologous T cell therapy in solid tumor patients
Hamilton, Erika, Nikiforow, Sarah, Bardwell, Philip, McInnis, Christine, Zhang, Jeffrey, Blumenschein, George, Cristea, Mihaela, Osman, Keren, Shields, Anthony, Motta, Marlyane, Bilic, Sanela, Schoenborn-Kellenberger, Oliver, Rakestraw, James, Carey, Shawn, Geretti, Elena, Sauer, Karsten, Harris, Tim, Maniar, Tap, Hewes, Becker, Andresen, Thomas, Fitzgerald, Jonathan, Kluger, Harriet
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
A structural and dynamic model for the interaction of interleukin-8 and glycosaminoglycans: Support from isothermal fluorescence titrations
Krieger, Elmar, Geretti, Elena, Brandner, Barbara, Goger, Birgit, Wells, Timothy N., Kungl, Andreas J.
Published in Proteins, structure, function, and bioinformatics (01.03.2004)
Published in Proteins, structure, function, and bioinformatics (01.03.2004)
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Journal Article
Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer
Espelin, Christopher W, Leonard, Shannon C, Geretti, Elena, Wickham, Thomas J, Hendriks, Bart S
Published in Cancer research (Chicago, Ill.) (15.03.2016)
Published in Cancer research (Chicago, Ill.) (15.03.2016)
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Journal Article
Safety and pharmacokinetics of MM-302, a HER2-targeted antibody-liposomal doxorubicin conjugate, in patients with advanced HER2-positive breast cancer: a phase 1 dose-escalation study
Munster, Pamela, Krop, Ian E, LoRusso, Patricia, Ma, Cynthia, Siegel, Barry A, Shields, Anthony F, Molnár, István, Wickham, Thomas J, Reynolds, Joseph, Campbell, Karen, Hendriks, Bart S, Adiwijaya, Bambang S, Geretti, Elena, Moyo, Victor, Miller, Kathy D
Published in British journal of cancer (01.10.2018)
Published in British journal of cancer (01.10.2018)
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Journal Article
Identification of the Glycosaminoglycan Binding Site of the CC Chemokine, MCP-1
Lau, Elaine K., Paavola, Chad D., Johnson, Zoë, Gaudry, Jean-Philippe, Geretti, Elena, Borlat, Frédéric, Kungl, Andreas J., Proudfoot, Amanda E., Handel, Tracy M.
Published in The Journal of biological chemistry (01.05.2004)
Published in The Journal of biological chemistry (01.05.2004)
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Journal Article
Abstract 2244: DeepIL-15 primed T cells synergize with PD-L1 blockade to overcome resistance to checkpoint immunotherapy
Geretti, Elena, Liang, Xiaoyan, Lyons, Jesse, Bardwell, Philip, Caruso, Santina, Hewes, Becker, Fitzgerald, Jonathan, Sauer, Karsten, Andresen, Thomas
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
DeepTM IL-15 Primed T cells Avoid Toxicity and Synergize with PD-L1 Blockade to Overcome Checkpoint Resistance in Cancer
Sauer, Karsten, Geretti, Elena, Liang, Xiaoyan, Lyons, Jesse, Bardwell, Philip, Caruso, Santina, Hewes, Becker, Fitzgerald, Jonathan, Andresen, Thomas
Published in The Journal of immunology (1950) (01.05.2019)
Published in The Journal of immunology (1950) (01.05.2019)
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Journal Article
Inflammation and Lymphedema Are Exacerbated and Prolonged by Neuropilin 2 Deficiency
Mucka, Patrick, Levonyak, Nicholas, Geretti, Elena, Zwaans, Bernadette M.M, Li, Xiaoran, Adini, Irit, Klagsbrun, Michael, Adam, Rosalyn M, Bielenberg, Diane R
Published in The American journal of pathology (01.11.2016)
Published in The American journal of pathology (01.11.2016)
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Journal Article
Abstract 3575: Cell therapy with surface-tethered IL-12 improves anti-tumor efficacy and activates the endogenous immune system
Nardozzi, Jon, Geretti, Elena, Chang, De-Kuan, McMillin, Douglas W., Lyons, Jesse, Nielsen, Ulrik, Andresen, Thomas, Jones, Douglas
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Single-Cell Quantitative HER2 Measurement Identifies Heterogeneity and Distinct Subgroups within Traditionally Defined HER2-Positive Patients
Onsum, Matthew D, Geretti, Elena, Paragas, Violette, Kudla, Arthur J, Moulis, Sharon P, Luus, Lia, Wickham, Thomas J, McDonagh, Charlotte F, MacBeath, Gavin, Hendriks, Bart S
Published in The American journal of pathology (01.11.2013)
Published in The American journal of pathology (01.11.2013)
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Journal Article
Nanoliposome targeting in breast cancer is influenced by the tumor microenvironment
Dumont, Nancy, Merrigan, Samantha, Turpin, Jason, Lavoie, Cynthia, Papavasiliou, Vasilios, Geretti, Elena, Espelin, Christopher W., Luus, Lia, Kamoun, Walid S., Ghasemi, Omid, Sahagian, G. Gary, Muller, William J., Hendriks, Bart S., Wickham, Thomas J., Drummond, Daryl C.
Published in Nanomedicine (01.04.2019)
Published in Nanomedicine (01.04.2019)
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Journal Article