Preclinical activity of the type II CD20 antibody GA101 (obinutuzumab) compared with rituximab and ofatumumab in vitro and in xenograft models
Herter, Sylvia, Herting, Frank, Mundigl, Olaf, Waldhauer, Inja, Weinzierl, Tina, Fauti, Tanja, Muth, Gunter, Ziegler-Landesberger, Doris, Van Puijenbroek, Erwin, Lang, Sabine, Duong, Minh Ngoc, Reslan, Lina, Gerdes, Christian A, Friess, Thomas, Baer, Ute, Burtscher, Helmut, Weidner, Michael, Dumontet, Charles, Umana, Pablo, Niederfellner, Gerhard, Bacac, Marina, Klein, Christian
Published in Molecular cancer therapeutics (01.10.2013)
Published in Molecular cancer therapeutics (01.10.2013)
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Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies
Grandjean, Capucine L, Montalvao, Fabricio, Celli, Susanna, Michonneau, David, Breart, Beatrice, Garcia, Zacarias, Perro, Mario, Freytag, Olivier, Gerdes, Christian A, Bousso, Philippe
Published in Scientific reports (04.10.2016)
Published in Scientific reports (04.10.2016)
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GA201 (RG7160): A Novel, Humanized, Glycoengineered Anti-EGFR Antibody with Enhanced ADCC and Superior In Vivo Efficacy Compared with Cetuximab
GERDES, Christian A, NICOLINI, Valeria Gonzalez, BOSSENMAIER, Birgit, MUELLER, Hans Joachim, UMANA, Pablo, HERTER, Sylvia, PUIJENBROEK, Erwin Van, LANG, Sabine, ROEMMELE, Michaela, MOESSNER, Ekkehard, FREYTAG, Olivier, FRIESS, Thomas, RIES, Carola H
Published in Clinical cancer research (01.03.2013)
Published in Clinical cancer research (01.03.2013)
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Journal Article
RG7116, a Therapeutic Antibody That Binds the Inactive HER3 Receptor and Is Optimized for Immune Effector Activation
MIRSCHBERGER, Christian, SCHILLER, Christian B, HOPFNER, Karl-Peter, NIEDERFELLNER, Gerhard, BOSSENMAIER, Birgit, SCHRÄML, Michael, DIMOUDIS, Nikolaos, FRIESS, Thomas, GERDES, Christian A, REIFF, Ulrike, LIFKE, Valeria, HOELZLWIMMER, Gabriele, KOLM, Irene
Published in Cancer research (Chicago, Ill.) (15.08.2013)
Published in Cancer research (Chicago, Ill.) (15.08.2013)
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Journal Article
Premedication and Chemotherapy Agents do not Impair Imgatuzumab (GA201)-Mediated Antibody-Dependent Cellular Cytotoxicity and Combination Therapies Enhance Efficacy
Gonzalez-Nicolini, Valeria, Herter, Sylvia, Lang, Sabine, Waldhauer, Inja, Bacac, Marina, Roemmele, Michaela, Bommer, Esther, Freytag, Olivier, van Puijenbroek, Erwin, Umaña, Pablo, Gerdes, Christian A
Published in Clinical cancer research (15.05.2016)
Published in Clinical cancer research (15.05.2016)
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In-anti-F4/80-A3-1 antibody: a novel tracer to image macrophages
Terry, Samantha Y A, Boerman, Otto C, Gerrits, Danny, Franssen, Gerben M, Metselaar, Josbert M, Lehmann, Steffi, Oyen, Wim J G, Gerdes, Christian A, Abiraj, Keelara
Published in European journal of nuclear medicine and molecular imaging (01.08.2015)
Published in European journal of nuclear medicine and molecular imaging (01.08.2015)
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Journal Article
Extracellular domain shedding influences specific tumor uptake and organ distribution of the EGFR PET tracer 89Zr-imgatuzumab
Pool, Martin, Kol, Arjan, Lub-de Hooge, Marjolijn N, Gerdes, Christian A, de Jong, Steven, de Vries, Elisabeth G E, Terwisscha van Scheltinga, Anton G T
Published in Oncotarget (18.10.2016)
Published in Oncotarget (18.10.2016)
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Efficient FLPe recombinase enables scalable production of helper-dependent adenoviral vectors with negligible helper-virus contamination
Lowenstein, Pedro R, Umaña, Pablo, Gerdes, Christian A, Stone, Daniel, Davis, Julian R.E, Ward, Daniel, Castro, Maria G
Published in Nature biotechnology (01.06.2001)
Published in Nature biotechnology (01.06.2001)
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Prolonged Blockade of CD40-CD40 Ligand Interactions by Gene Transfer of CD40Ig Results in Long-Term Heart Allograft Survival and Donor-Specific Hyporesponsiveness, But Does Not Prevent Chronic Rejection
Guillot, Cecile, Guillonneau, Carole, Mathieu, Patrick, Gerdes, Christian A, Menoret, Severine, Braudeau, Cecile, Tesson, Laurent, Renaudin, Karine, Castro, Maria G, Lowenstein, Pedro R, Anegon, Ignacio
Published in The Journal of immunology (1950) (15.02.2002)
Published in The Journal of immunology (1950) (15.02.2002)
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Abstract 4511: Differential effects of GA201 and cetuximab on EGFR expression and endosomal recycling in non-small cell lung cancer cell lines
Kol, Arjan, Jong, Steven de, Pool, Martin, Vries, Elisabeth G.E. de, Gerdes, Christian A., Scheltinga, Anton G.T. Terwisscha van
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract A86: Extracellular domain shedding influences specific tumor uptake and kinetics of EGFR PET tracer 89Zr-imgatuzumab
Pool, Martin, Kol, Arjan, Lub-de Hooge, Marjolijn N., Gerdes, Christian A., de Jong, Steven, de Vries, Elisabeth G.E., Terwisscha van Scheltinga, Anton G.T.
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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Abstract 4931: ImmunoPET and fluorescence imaging with Zirconium-89 and IRDye 800CW labeled glycoengineered epidermal growth factor receptor antibody GA201
Pool, Martin, Kol, Arjan, Hooge, Marjolijn N. Lub-De, Gerdes, Christian A., Jong, Steven de, Vries, Elisabeth G.E. de, Scheltinga, Anton G.T. Terwisscha van
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
super(111)In-anti-F4/80-A3-1 antibody: a novel tracer to image macrophages
Terry, Samantha YA, Boerman, Otto C, Gerrits, Danny, Franssen, Gerben M, Metselaar, Josbert M, Lehmann, Steffi, Oyen, Wim JG, Gerdes, Christian A, Abiraj, Keelara
Published in European journal of nuclear medicine and molecular imaging (01.08.2015)
Published in European journal of nuclear medicine and molecular imaging (01.08.2015)
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Journal Article
sup 111^In-anti-F4/80-A3-1 antibody: a novel tracer to image macrophages
Terry, Samantha Y; A, Boerman, Otto C, Gerrits, Danny, Franssen, Gerben M, Metselaar, Josbert M, Lehmann, Steffi, Oyen, Wim J; G, Gerdes, Christian A, Abiraj, Keelara
Published in European journal of nuclear medicine and molecular imaging (01.08.2015)
Published in European journal of nuclear medicine and molecular imaging (01.08.2015)
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Journal Article
111In-anti-F4/80-A3-1 antibody: a novel tracer to image macrophages
Terry, Samantha Y. A., Boerman, Otto C., Gerrits, Danny, Franssen, Gerben M., Metselaar, Josbert M., Lehmann, Steffi, Oyen, Wim J. G., Gerdes, Christian A., Abiraj, Keelara
Published in European journal of nuclear medicine and molecular imaging (2015)
Published in European journal of nuclear medicine and molecular imaging (2015)
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Journal Article
Abstract A156: GA201 (RG7160) pretreatments and combination therapies improve efficacy without negatively affecting antitumoral ADCC
Nicolini, Valeria, Herter, Sylvia, Lang, Sabine, Walhauer, Inja, van Puijenbroek, Erwin, Dunn, Claire, Umana, Pablo, Gerdes, Christian A.
Published in Molecular cancer therapeutics (12.11.2011)
Published in Molecular cancer therapeutics (12.11.2011)
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Strong Promoters Are the Key to Highly Efficient, Noninflammatory and Noncytotoxic Adenoviral-Mediated Transgene Delivery into the Brain in Vivo: Volume 2, Number 4 (2000), pages 330-338
Gerdes, Christian A, Castro, Maria G, Löwenstein, Pedro R
Published in Molecular therapy (01.12.2000)
Published in Molecular therapy (01.12.2000)
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Journal Article
Fts insertional mutant of Salmonella typhimurium
Cerquetti, M.Cristina, Brawer, Rolando, Gerdes, Christian A., Gherardi, M.Magdalena, Sordelli, Daniel O.
Published in FEMS microbiology letters (01.10.1995)
Published in FEMS microbiology letters (01.10.1995)
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