The metalloprotease ADAMTS4 generates N-truncated Aβ4–x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer’s disease
Walter, Susanne, Jumpertz, Thorsten, Hüttenrauch, Melanie, Ogorek, Isabella, Gerber, Hermeto, Storck, Steffen E., Zampar, Silvia, Dimitrov, Mitko, Lehmann, Sandra, Lepka, Klaudia, Berndt, Carsten, Wiltfang, Jens, Becker-Pauly, Christoph, Beher, Dirk, Pietrzik, Claus U., Fraering, Patrick C., Wirths, Oliver, Weggen, Sascha
Published in Acta neuropathologica (01.02.2019)
Published in Acta neuropathologica (01.02.2019)
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Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence
Revandkar, Ajinkya, Perciato, Maria Luna, Toso, Alberto, Alajati, Abdullah, Chen, Jingjing, Gerber, Hermeto, Dimitrov, Mitko, Rinaldi, Andrea, Delaleu, Nicolas, Pasquini, Emiliano, D'Antuono, Rocco, Pinton, Sandra, Losa, Marco, Gnetti, Letizia, Arribas, Alberto, Fraering, Patrick, Bertoni, Francesco, Nepveu, Alain, Alimonti, Andrea
Published in Nature communications (12.12.2016)
Published in Nature communications (12.12.2016)
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Induction of Amyloid-β42 Production by Fipronil and Other Pyrazole Insecticides
Cam, Morgane, Durieu, Emilie, Bodin, Marion, Manousopoulou, Antigoni, Koslowski, Svenja, Vasylieva, Natalia, Barnych, Bogdan, Hammock, Bruce D, Bohl, Bettina, Koch, Philipp, Omori, Chiori, Yamamoto, Kazuo, Hata, Saori, Suzuki, Toshiharu, Karg, Frank, Gizzi, Patrick, Erakovic Haber, Vesna, Bencetic Mihaljevic, Vlatka, Tavcar, Branka, Portelius, Erik, Pannee, Josef, Blennow, Kaj, Zetterberg, Henrik, Garbis, Spiros D, Auvray, Pierrick, Gerber, Hermeto, Fraering, Jeremy, Fraering, Patrick C, Meijer, Laurent
Published in Journal of Alzheimer's disease (2018)
Published in Journal of Alzheimer's disease (2018)
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The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease
Gerber, Hermeto, Mosser, Sebastien, Boury-Jamot, Benjamin, Stumpe, Michael, Piersigilli, Alessandra, Goepfert, Christine, Dengjel, Joern, Albrecht, Urs, Magara, Fulvio, Fraering, Patrick C
Published in Acta neuropathologica communications (31.01.2019)
Published in Acta neuropathologica communications (31.01.2019)
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Zinc and Copper Differentially Modulate Amyloid Precursor Protein Processing by γ-Secretase and Amyloid-β Peptide Production
Gerber, Hermeto, Wu, Fang, Dimitrov, Mitko, Garcia Osuna, Guillermo M., Fraering, Patrick C.
Published in The Journal of biological chemistry (03.03.2017)
Published in The Journal of biological chemistry (03.03.2017)
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Journal Article
The metalloprotease ADAMTS4 generates N-truncated A[beta]4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease
Walter, Susanne, Jumpertz, Thorsten, Hüttenrauch, Melanie, Ogorek, Isabella, Gerber, Hermeto, Storck, Steffen E, Zampar, Silvia
Published in Acta neuropathologica (01.02.2019)
Published in Acta neuropathologica (01.02.2019)
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Journal Article
The lipidome associated with the γ-secretase complex is required for its integrity and activity
Ayciriex, Sophie, Gerber, Hermeto, Osuna, Guillermo M Garcia, Chami, Mohamed, Stahlberg, Henning, Shevchenko, Andrej, Fraering, Patrick C
Published in Biochemical journal (01.02.2016)
Published in Biochemical journal (01.02.2016)
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Journal Article
Production of active glycosylation-deficient [gamma]-secretase complex for crystallization studies
López, Andrés Ricardo, Dimitrov, Mitko, Gerber, Hermeto, Braman, Virginie, Hacker, David L, Wurm, Florian M, Fraering, Patrick C
Published in Biotechnology and bioengineering (01.12.2015)
Published in Biotechnology and bioengineering (01.12.2015)
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Journal Article
Production of active glycosylation-deficient γ-secretase complex for crystallization studies
López, Andrés Ricardo, Dimitrov, Mitko, Gerber, Hermeto, Braman, Virginie, Hacker, David L., Wurm, Florian M., Fraering, Patrick C.
Published in Biotechnology and bioengineering (01.12.2015)
Published in Biotechnology and bioengineering (01.12.2015)
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