Circulating Nucleosomes and Neutrophil Activation as Risk Factors for Deep Vein Thrombosis
van Montfoort, Maurits L, Stephan, Femke, Lauw, Mandy N, Hutten, Barbara A, Van Mierlo, Gerard J, Solati, Shabnam, Middeldorp, Saskia, Meijers, Joost C.M, Zeerleder, Sacha
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2013)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2013)
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Nucleosomes and neutrophil activation in sickle cell disease painful crisis
Schimmel, Marein, Nur, Erfan, Biemond, Bart J, van Mierlo, Gerard J, Solati, Shabnam, Brandjes, Dees P, Otten, Hans-Martin, Schnog, John-John, Zeerleder, Sacha
Published in Haematologica (Roma) (01.11.2013)
Published in Haematologica (Roma) (01.11.2013)
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Activated protein C inhibits neutrophil migration in allergic asthma: a randomised trial
de Boer, J Daan, Berger, Marieke, Majoor, Christof J, Kager, Liesbeth M, Meijers, Joost C M, Terpstra, Sanne, Nieuwland, Rienk, Boing, Anita N, Lutter, René, Wouters, Diana, van Mierlo, Gerard J, Zeerleder, Sacha S, Bel, Elisabeth H, van't Veer, Cornelis, de Vos, Alex F, van der Zee, Jaring S, van der Poll, Tom
Published in The European respiratory journal (01.12.2015)
Published in The European respiratory journal (01.12.2015)
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The effects of tidal volume size and driving pressure levels on pulmonary complement activation: an observational study in critically ill patients
de Beer, Friso M., Wieske, Luuk, van Mierlo, Gerard, Wouters, Diana, Zeerleder, Sacha, Bos, Lieuwe D., Juffermans, Nicole P., Schultz, Marcus J., van der Poll, Tom, Lagrand, Wim K., Horn, Janneke
Published in Intensive care medicine experimental (18.12.2020)
Published in Intensive care medicine experimental (18.12.2020)
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S100A8/A9 Is a Marker for the Release of Neutrophil Extracellular Traps and Induces Neutrophil Activation
Sprenkeler, Evelien G G, Zandstra, Judith, van Kleef, Nadine D, Goetschalckx, Ines, Verstegen, Bibian, Aarts, Cathelijn E M, Janssen, Hans, Tool, Anton T J, van Mierlo, Gerard, van Bruggen, Robin, Jongerius, Ilse, Kuijpers, Taco W
Published in Cells (Basel, Switzerland) (11.01.2022)
Published in Cells (Basel, Switzerland) (11.01.2022)
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The relation between fibrinogen level, neutrophil activity and nucleosomes in the onset of disseminated intravascular coagulation in the critically ill
Müller, Marcella C.A., Dujardin, Romein W.G., Thachil, Jecko, Mierlo, Gerard, Zeerleder, Sacha S., Juffermans, Nicole P.
Published in Journal of internal medicine (01.10.2021)
Published in Journal of internal medicine (01.10.2021)
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Biomarkers to predict infection and infection‐related complications during chemotherapy‐induced neutropenia in acute myeloid leukaemia: a pilot study
Geer, Annemarie, Zandstra, Judith, Tanck, Michael W. T., Nur, Erfan, Mierlo, Gerard, Jongerius, Ilse, Bruggen, Robin, Zeerleder, Sacha S., Kuijpers, Taco W.
Published in British journal of haematology (01.06.2021)
Published in British journal of haematology (01.06.2021)
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Immunothrombosis and Complement Activation Contribute to Disease Severity and Adverse Outcome in COVID-19
Ruggeri, Tiphaine, De Wit, Yasmin, Schärz, Noëlia, van Mierlo, Gerard, Angelillo-Scherrer, Anne, Brodard, Justine, Schefold, Joerg C., Hirzel, Cédric, Jongerius, Ilse, Zeerleder, Sacha
Published in Journal of innate immunity (01.01.2023)
Published in Journal of innate immunity (01.01.2023)
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Complement factor H contributes to mortality in humans and mice with bacterial meningitis
Kasanmoentalib, E Soemirien, Valls Serón, Mercedes, Engelen-Lee, Joo Yeon, Tanck, Michael W, Pouw, Richard B, van Mierlo, Gerard, Wouters, Diana, Pickering, Matthew C, van der Ende, Arie, Kuijpers, Taco W, Brouwer, Matthijs C, van de Beek, Diederik
Published in Journal of neuroinflammation (28.12.2019)
Published in Journal of neuroinflammation (28.12.2019)
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Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma
van Beek, Anna E, Pouw, Richard B, Brouwer, Mieke C, van Mierlo, Gerard, Geissler, Judy, Ooijevaar-de Heer, Pleuni, de Boer, Martin, van Leeuwen, Karin, Rispens, Theo, Wouters, Diana, Kuijpers, Taco W
Published in Frontiers in immunology (18.10.2017)
Published in Frontiers in immunology (18.10.2017)
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Effect of C1‐inhibitor in adults with mild asthma: A randomized controlled trial
Yang, Jack, Engelen, Tjitske S. R., Haak, Bastiaan W., Bonta, Peter I., Majoor, Christof J., Veer, Cornelis, Vos, Alex F., Kemper, E. Marleen, Lutter, René, Mierlo, Gerard, Zeerleder, Sacha S., Bel, Elisabeth H., Poll, Tom
Published in Allergy (Copenhagen) (01.04.2020)
Published in Allergy (Copenhagen) (01.04.2020)
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Dynamics of antibodies to SARS‐CoV‐2 in convalescent plasma donors
Steenhuis, Maurice, Mierlo, Gerard, Derksen, Ninotska IL, Ooijevaar‐de Heer, Pleuni, Kruithof, Simone, Loeff, Floris L, Berkhout, Lea C, Linty, Federica, Reusken, Chantal, Reimerink, Johan, Hogema, Boris, Zaaijer, Hans, Watering, Leo, Swaneveld, Francis, Gils, Marit J, Bosch, Berend Jan, Ham, S Marieke, Brinke, Anja, Vidarsson, Gestur, Schoot, Ellen C, Rispens, Theo
Published in Clinical & translational immunology (2021)
Published in Clinical & translational immunology (2021)
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Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes
Keizer, Mischa P, Kamp, Angela, van Mierlo, Gerard, Kuijpers, Taco W, Wouters, Diana
Published in Frontiers in immunology (27.06.2018)
Published in Frontiers in immunology (27.06.2018)
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Journal Article
Sugar Matters: Improving In Vivo Clearance Rate of Highly Glycosylated Recombinant Plasma Proteins for Therapeutic Use
Zeerleder, Sacha, Engel, Ruchira, Zhang, Tao, Roem, Dorina, van Mierlo, Gerard, Wagenaar-Bos, Ineke, van Ham, Sija Marieke, Wuhrer, Manfred, Wouters, Diana, Jongerius, Ilse
Published in Pharmaceuticals (Basel, Switzerland) (11.01.2021)
Published in Pharmaceuticals (Basel, Switzerland) (11.01.2021)
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Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice
Stroo, Ingrid, Yang, Jack, Anas, Adam A, de Boer, J Daan, van Mierlo, Gerard, Roem, Dorina, Wouters, Diana, Engel, Ruchira, Roelofs, Joris J T H, van 't Veer, Cornelis, van der Poll, Tom, Zeerleder, Sacha
Published in PloS one (16.10.2017)
Published in PloS one (16.10.2017)
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Journal Article
Increased intra- and extracellular granzyme expression in patients with tuberculosis
Garcia-Laorden, M. Isabel, Blok, Dana C, Kager, Liesbeth M, Hoogendijk, Arie J, van Mierlo, Gerard J, Lede, Ivar O, Rahman, Wahid, Afroz, Rumana, Ghose, Aniruddha, Visser, Caroline E, Md Zahed, Abu Shahed, Husain, Md Anwar, Alam, Khan Mashrequl, Chandra Barua, Pravat, Hassan, Mahtabuddin, Hossain, Ahmed, Tayab, Md Abu, Day, Nick, Dondorp, Arjen M, de Vos, Alex F, van der Poll, Tom
Published in Tuberculosis (Edinburgh, Scotland) (01.09.2015)
Published in Tuberculosis (Edinburgh, Scotland) (01.09.2015)
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Journal Article
Administration of C1 Inhibitor Reduces Neutrophil Activation in Patients with Sepsis
Zeerleder, Sacha, Caliezi, Christoph, van Mierlo, Gerard, Eerenberg-Belmer, Anke, Sulzer, Irmela, Hack, C. Erik, Wuillemin, Walter A.
Published in Clinical and Diagnostic Laboratory Immunology (01.07.2003)
Published in Clinical and Diagnostic Laboratory Immunology (01.07.2003)
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Rat C‐reactive protein activates the autologous complement system
Padilla, Niubel Diaz, Bleeker, Wim K., Lubbers, Yvonne, Rigter, Gemma M. M., Van Mierlo, Gerard J., Daha, Mohamed R., Hack, C. Erik
Published in Immunology (01.08.2003)
Published in Immunology (01.08.2003)
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Complement Activation in Relation to Capillary Leakage in Children with Septic Shock and Purpura
HAZELZET, J. A, DE GROOT, R, VAN MIERLO, G, JOOSTEN, K. F. M, VAN DER VOORT, E, EERENBERG, A, SUUR, M. H, HOP, W. C. J, HACK, C. E
Published in Infection and Immunity (01.11.1998)
Published in Infection and Immunity (01.11.1998)
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Fc Galactosylation Promotes Hexamerization of Human IgG1, Leading to Enhanced Classical Complement Activation
van Osch, Thijs L. J., Nouta, Jan, Derksen, Ninotska I. L., van Mierlo, Gerard, van der Schoot, C. Ellen, Wuhrer, Manfred, Rispens, Theo, Vidarsson, Gestur
Published in The Journal of immunology (1950) (15.09.2021)
Published in The Journal of immunology (1950) (15.09.2021)
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