PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments
Tanjoni, Isabelle, Walsh, Colin, Uryu, Sean, Tomar, Alok, Nam, Ju-Ock, Mielgo, Ainhoa, Lim, Ssang-Taek, Liang, Congxin, Koenig, Marcel, Patel, Neela, Kwok, Cheni, McMahon, Gerald, Stupack, Dwayne G., Schlaepfer, David D.
Published in Cancer biology & therapy (15.05.2010)
Published in Cancer biology & therapy (15.05.2010)
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ErbB activation signatures as potential biomarkers for anti-ErbB3 treatment in HNSCC
Alvarado, Diego, Ligon, Gwenda F, Lillquist, Jay S, Seibel, Scott B, Wallweber, Gerald, Neumeister, Veronique M, Rimm, David L, McMahon, Gerald, LaVallee, Theresa M
Published in PloS one (19.07.2017)
Published in PloS one (19.07.2017)
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Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models
Walsh, Colin, Tanjoni, Isabelle, Uryu, Sean, Tomar, Alok, Nam, Ju-Ock, Luo, Hong, Phillips, Angelica, Patel, Neela, Kwok, Cheni, McMahon, Gerald, Stupack, Dwayne G., Schlaepfer, David D.
Published in Cancer biology & therapy (15.05.2010)
Published in Cancer biology & therapy (15.05.2010)
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Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis
Abdollahi, Amir, Li, Minglun, Ping, Gong, Plathow, Christian, Domhan, Sophie, Kiessling, Fabian, Lee, Leslie B, McMahon, Gerald, Gröne, Hermann-Josef, Lipson, Kenneth E, Huber, Peter E
Published in The Journal of experimental medicine (21.03.2005)
Published in The Journal of experimental medicine (21.03.2005)
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Phase I Dose-Escalating Study of SU11654, a Small Molecule Receptor Tyrosine Kinase Inhibitor, in Dogs with Spontaneous Malignancies
LONDON, Cheryl A, HANNAH, Alison L, MENDEL, Dirk B, MCMAHON, Gerald, CHERRINGTON, Julie M, ZADOVOSKAYA, Regina, CHIEN, May B, KOLLIAS-BAKER, Cynthia, ROSENBERG, Mona, DOWNING, Sue, POST, Gerald, BOUCHER, Joseph, SHENOY, Narmada
Published in Clinical cancer research (01.07.2003)
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Published in Clinical cancer research (01.07.2003)
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SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase
Yee, Kevin W.H., O'Farrell, Anne Marie, Smolich, Beverly D., Cherrington, Julie M., McMahon, Gerald, Wait, Cecily L., McGreevey, Laura S., Griffith, Diana J., Heinrich, Michael C.
Published in Blood (15.10.2002)
Published in Blood (15.10.2002)
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Design, Synthesis, and Evaluations of Substituted 3-[(3- or 4-Carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as Inhibitors of VEGF, FGF, and PDGF Receptor Tyrosine Kinases
Sun, Li, Tran, Ngoc, Liang, Congxin, Tang, Flora, Rice, Audie, Schreck, Randall, Waltz, Kara, Shawver, Laura K, McMahon, Gerald, Tang, Cho
Published in Journal of medicinal chemistry (16.12.1999)
Published in Journal of medicinal chemistry (16.12.1999)
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Differential Activation of Peroxisome Proliferator-activated Receptors by Eicosanoids (∗)
Yu, Ker, Bayona, William, Kallen, Caleb B., Harding, Heather P., Ravera, Christina P., McMahon, Gerald, Brown, Myles, Lazar, Mitchell A.
Published in The Journal of biological chemistry (13.10.1995)
Published in The Journal of biological chemistry (13.10.1995)
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Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasion
Wang, Xueyan, Le, Phuong, Liang, Congxin, Chan, Julie, Kiewlich, David, Miller, Todd, Harris, Dave, Sun, Li, Rice, Audie, Vasile, Stefan, Blake, Robert A, Howlett, Anthony R, Patel, Neela, McMahon, Gerald, Lipson, Kenneth E
Published in Molecular cancer therapeutics (01.11.2003)
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Published in Molecular cancer therapeutics (01.11.2003)
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Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival
Reinmuth, N, Liu, W, Jung, Y D, Ahmad, S A, Shaheen, R M, Fan, F, Bucana, C D, McMahon, G, Gallick, G E, Ellis, L M
Published in The FASEB journal (01.05.2001)
Published in The FASEB journal (01.05.2001)
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Troglitazone induces a rapid drop of mitochondrial membrane potential in liver HepG2 cells
Bova, Michael P., Tam, Danny, McMahon, Gerald, Mattson, Matthew N.
Published in Toxicology letters (01.01.2005)
Published in Toxicology letters (01.01.2005)
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FGF10 is an inducer and Pax6 a competence factor for lacrimal gland development
Makarenkova, H P, Ito, M, Govindarajan, V, Faber, S C, Sun, L, McMahon, G, Overbeek, P A, Lang, R A
Published in Development (Cambridge) (01.06.2000)
Published in Development (Cambridge) (01.06.2000)
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Tyrphostins. 5. Potent Inhibitors of Platelet-Derived Growth Factor Receptor Tyrosine Kinase: Structure−Activity Relationships in Quinoxalines, Quinolines, and Indole Tyrphostins
Gazit, Aviv, App, Harald, McMahon, Gerald, Chen, Jefferey, Levitzki, Alexander, Bohmer, Frank D
Published in Journal of medicinal chemistry (24.05.1996)
Published in Journal of medicinal chemistry (24.05.1996)
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Structure-Based design and discovery of novel inhibitors of protein tyrosine phosphatases
Huang, Ping, Ramphal, John, Wei, James, Liang, Congxin, Jallal, Bahija, McMahon, Gerald, Tang, Cho
Published in Bioorganic & medicinal chemistry (17.04.2003)
Published in Bioorganic & medicinal chemistry (17.04.2003)
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SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization
ISMAIL, Ismail Hassan, MARTENSSON, Susanne, MOSHINSKY, Deborah, RICE, Audie, CHO TANG, HOWLETT, Anthony, MCMAHON, Gerald, HAMMARSTEN, Ola
Published in Oncogene (29.01.2004)
Published in Oncogene (29.01.2004)
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A Selective and Oral Small Molecule Inhibitor of Vascular Epithelial Growth Factor Receptor (VEGFR)-2 and VEGFR-1 Inhibits Neovascularization and Vascular Permeability
Patel, Neela, Sun, Li, Moshinsky, Deborah, Chen, Hui, Leahy, Kathleen M, Le, Phuong, Moss, Katherine G, Wang, Xueyan, Rice, Audie, Tam, Danny, Laird, A Douglas, Yu, Xiaoming, Zhang, Qingling, Tang, Cho, McMahon, Gerald, Howlett, Anthony
Published in The Journal of pharmacology and experimental therapeutics (01.09.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2003)
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Improved Effect of an Antiangiogenic Tyrosine Kinase Inhibitor (SU5416) by Combinations with Fractionated Radiotherapy or Low Molecular Weight Heparin
Lund, Eva L., Olsen, Minna W.B., Lipson, Kenneth E., McMahon, Gerald, Howlett, Anthony R., Kristjansen, Paul E.G.
Published in Neoplasia (New York, N.Y.) (01.03.2003)
Published in Neoplasia (New York, N.Y.) (01.03.2003)
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