ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage
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Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening
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N-((8-Hydroxy-5-substituted-quinolin-7-yl)(phenyl)methyl)-2-phenyloxy/amino-acetamide inhibitors of ADAMTS-5 (Aggrecanase-2)
Gilbert, Adam M., Bursavich, Matthew G., Lombardi, Sabrina, Georgiadis, Katy E., Reifenberg, Erica, Flannery, Carl R., Morris, Elisabeth A.
Published in Bioorganic & medicinal chemistry (15.12.2008)
Published in Bioorganic & medicinal chemistry (15.12.2008)
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5-((1 H-Pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one inhibitors of ADAMTS-5
Gilbert, Adam M., Bursavich, Matthew G., Lombardi, Sabrina, Georgiadis, Katy E., Reifenberg, Erica, Flannery, Carl R., Morris, Elisabeth A.
Published in Bioorganic & medicinal chemistry letters (01.03.2007)
Published in Bioorganic & medicinal chemistry letters (01.03.2007)
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5'-Phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one inhibitors of ADAMTS-5 (aggrecanase-2)
Bursavich, Matthew G, Gilbert, Adam M, Lombardi, Sabrina, Georgiadis, Katy E, Reifenberg, Erica, Flannery, Carl R, Morris, Elisabeth A
Published in Bioorganic & medicinal chemistry letters (15.10.2007)
Published in Bioorganic & medicinal chemistry letters (15.10.2007)
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Synthesis and evaluation of aryl thioxothiazolidinone inhibitors of ADAMTS-5 (Aggrecanase-2)
Bursavich, Matthew G., Gilbert, Adam M., Lombardi, Sabrina, Georgiadis, Katy E., Reifenberg, Erica, Flannery, Carl R., Morris, Elisabeth A.
Published in Bioorganic & medicinal chemistry letters (01.03.2007)
Published in Bioorganic & medicinal chemistry letters (01.03.2007)
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Synthesis and biological evaluation of ((4-keto)-phenoxy)methyl biphenyl-4-sulfonamides: A class of potent aggrecanase-1 inhibitors
Hopper, Darrin W., Vera, Matthew D., How, David, Sabatini, Joshua, Xiang, Jason S., Ipek, Manus, Thomason, Jennifer, Hu, Yonghan, Feyfant, Eric, Wang, Qin, Georgiadis, Katy E., Reifenberg, Erica, Sheldon, Richard T., Keohan, Cristin C., Majumdar, Manas K., Morris, Elisabeth A., Skotnicki, Jerauld, Sum, Phaik-Eng
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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Intramolecular Electron Transfer and Conformational Changes in Cytochrome c Oxidase
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Published in Biochemistry (Easton) (01.01.1995)
Published in Biochemistry (Easton) (01.01.1995)
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Continued exploration of biphenylsulfonamide scaffold as a platform for aggrecanase-1 inhibition
Hu, Yonghan, Xing, Li, Thomason, Jennifer R., Xiang, Jason, Ipek, Manus, Guler, Satenig, Li, Huanqiu, Sabatini, Joshua, Chockalingam, Priya, Reifenberg, Erica, Sheldon, Richard, Morris, Elisabeth A., Georgiadis, Katy E., Tam, Steve
Published in Bioorganic & medicinal chemistry letters (15.11.2011)
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Time-Resolved Optical Absorption Studies of Intramolecular Electron Transfer in Cytochrome c Oxidase
Georgiadis, Katy E, Jhon, Nam-In, Einarsdottir, Olof
Published in Biochemistry (Easton) (01.08.1994)
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Interleukin 1 (IL-1) Causes Changes in Lateral and Rotational Mobilities of IL-1 Type I Receptors
Guo, Chunmei, Georgiadis, Katy E, Dower, Steven K, Holowka, David, Baird, Barbara A
Published in Biochemistry (Easton) (02.02.1999)
Published in Biochemistry (Easton) (02.02.1999)
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5′-Phenyl-3′H-spiro[indoline-3,2′-[1,3,4]thiadiazol]-2-one inhibitors of ADAMTS-5 (Aggrecanase-2)
Bursavich, Matthew G., Gilbert, Adam M., Lombardi, Sabrina, Georgiadis, Katy E., Reifenberg, Erica, Flannery, Carl R., Morris, Elisabeth A.
Published in Bioorganic & medicinal chemistry letters (15.10.2007)
Published in Bioorganic & medicinal chemistry letters (15.10.2007)
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5' -Penyl-3'H -spiro[indoline -3,2-[1,3,4]thiadiazol]-2 -one inhibitors of ADATS-5 (aggrecanase-2)
BURSAVICH, Matthew G, GILBERT, Adam M, LOMBARDI, Sabrina, GEORGIADIS, Katy E, REIFENBERG, Erica, FLANNERY, Carl R, MORRIS, Elisabeth A
Published in Bioorganic & medicinal chemistry letters (2007)
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Published in Bioorganic & medicinal chemistry letters (2007)
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