Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina
Gonzalez-Cordero, Anai, West, Emma L, Pearson, Rachael A, Duran, Yanai, Carvalho, Livia S, Chu, Colin J, Naeem, Arifa, Blackford, Samuel J I, Georgiadis, Anastasios, Lakowski, Jorn, Hubank, Mike, Smith, Alexander J, Bainbridge, James W B, Sowden, Jane C, Ali, Robin R
Published in Nature biotechnology (01.08.2013)
Published in Nature biotechnology (01.08.2013)
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Journal Article
AAV-RPGR Gene Therapy Rescues Opsin Mislocalisation in a Human Retinal Organoid Model of RPGR -Associated X-Linked Retinitis Pigmentosa
Sladen, Paul E, Naeem, Arifa, Adefila-Ideozu, Toyin, Vermeule, Tijmen, Busson, Sophie L, Michaelides, Michel, Naylor, Stuart, Forbes, Alexandria, Lane, Amelia, Georgiadis, Anastasios
Published in International journal of molecular sciences (01.02.2024)
Published in International journal of molecular sciences (01.02.2024)
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Journal Article
Use of bioreactors for culturing human retinal organoids improves photoreceptor yields
Ovando-Roche, Patrick, West, Emma L, Branch, Matthew J, Sampson, Robert D, Fernando, Milan, Munro, Peter, Georgiadis, Anastasios, Rizzi, Matteo, Kloc, Magdalena, Naeem, Arifa, Ribeiro, Joana, Smith, Alexander J, Gonzalez-Cordero, Anai, Ali, Robin R
Published in Stem cell research & therapy (13.06.2018)
Published in Stem cell research & therapy (13.06.2018)
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Journal Article
Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration
Kruczek, Kamil, Gonzalez-Cordero, Anai, Goh, Debbie, Naeem, Arifa, Jonikas, Mindaugas, Blackford, Samuel J.I., Kloc, Magdalena, Duran, Yanai, Georgiadis, Anastasios, Sampson, Robert D., Maswood, Ryea N., Smith, Alexander J., Decembrini, Sarah, Arsenijevic, Yvan, Sowden, Jane C., Pearson, Rachael A., West, Emma L., Ali, Robin R.
Published in Stem cell reports (06.06.2017)
Published in Stem cell reports (06.06.2017)
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Journal Article
Modulation of Contact Inhibition by ZO-1/ZONAB Gene Transfer-A New Strategy to Increase the Endothelial Cell Density of Corneal Grafts
Kampik, Daniel, Basche, Mark, Georgiadis, Anastasios, Luhmann, Ulrich F O, Larkin, D Frank, Smith, Alexander J, Ali, Robin R
Published in Investigative ophthalmology & visual science (01.07.2019)
Published in Investigative ophthalmology & visual science (01.07.2019)
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Journal Article
Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration
Athanasiou, Dimitra, Aguila, Monica, Opefi, Chikwado A, South, Kieron, Bellingham, James, Bevilacqua, Dalila, Munro, Peter M, Kanuga, Naheed, Mackenzie, Francesca E, Dubis, Adam M, Georgiadis, Anastasios, Graca, Anna B, Pearson, Rachael A, Ali, Robin R, Sakami, Sanae, Palczewski, Krzysztof, Sherman, Michael Y, Reeves, Philip J, Cheetham, Michael E
Published in Human molecular genetics (15.01.2017)
Published in Human molecular genetics (15.01.2017)
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Journal Article
Effective AAV-mediated gene replacement therapy in retinal organoids modeling AIPL1-associated LCA4
Sai, Hali, Ollington, Bethany, Rezek, Farah O., Chai, Niuzheng, Lane, Amelia, Georgiadis, Anastasios, Bainbridge, James, Michaelides, Michel, Sacristan-Reviriego, Almudena, Perdigão, Pedro R.L., Leung, Amy, van der Spuy, Jacqueline
Published in Molecular therapy. Nucleic acids (12.03.2024)
Published in Molecular therapy. Nucleic acids (12.03.2024)
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Journal Article
Regulation of PCNA and Cyclin D1 Expression and Epithelial Morphogenesis by the ZO-1-Regulated Transcription Factor ZONAB/DbpA
Sourisseau, Tony, Georgiadis, Anastasios, Tsapara, Anna, Ali, Robin R., Pestell, Richard, Matter, Karl, Balda, Maria S.
Published in Molecular and Cellular Biology (01.03.2006)
Published in Molecular and Cellular Biology (01.03.2006)
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Journal Article
The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice
Georgiadis, Anastasios, Tschernutter, Marion, Bainbridge, James W B, Balaggan, Kamaljit S, Mowat, Freya, West, Emma L, Munro, Peter M G, Thrasher, Adrian J, Matter, Karl, Balda, Maria S, Ali, Robin R
Published in PloS one (30.12.2010)
Published in PloS one (30.12.2010)
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Journal Article
Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration
Ovando-Roche, Patrick, Georgiadis, Anastasios, Smith, Alexander J., Pearson, Rachael A., Ali, Robin R.
Published in Current stem cell reports (01.06.2017)
Published in Current stem cell reports (01.06.2017)
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Journal Article
Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development
Lange, Clemens A K, Luhmann, Ulrich F O, Mowat, Freya M, Georgiadis, Anastasios, West, Emma L, Abrahams, Sabu, Sayed, Haroon, Powner, Michael B, Fruttiger, Marcus, Smith, Alexander J, Sowden, Jane C, Maxwell, Patrick H, Ali, Robin R, Bainbridge, James W B
Published in Development (Cambridge) (01.07.2012)
Published in Development (Cambridge) (01.07.2012)
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Journal Article
Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis
Bainbridge, James W.B, Mehat, Manjit S, Sundaram, Venki, Robbie, Scott J, Barker, Susie E, Ripamonti, Caterina, Georgiadis, Anastasios, Mowat, Freya M, Beattie, Stuart G, Gardner, Peter J, Feathers, Kecia L, Luong, Vy A, Yzer, Suzanne, Balaggan, Kamaljit, Viswanathan, Ananth, de Ravel, Thomy J.L, Casteels, Ingele, Holder, Graham E, Tyler, Nick, Fitzke, Fred W, Weleber, Richard G, Nardini, Marko, Moore, Anthony T, Thompson, Debra A, Petersen-Jones, Simon M, Michaelides, Michel, van den Born, L. Ingeborgh, Stockman, Andrew, Smith, Alexander J, Rubin, Gary, Ali, Robin R
Published in The New England journal of medicine (14.05.2015)
Published in The New England journal of medicine (14.05.2015)
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Journal Article
AAV-RPGR Gene Therapy Rescues Opsin Mislocalisation in a Human Retinal Organoid Model of IRPGR/I-Associated X-Linked Retinitis Pigmentosa
Sladen, Paul E, Naeem, Arifa, Adefila-Ideozu, Toyin, Vermeule, Tijmen, Busson, Sophie L, Michaelides, Michel, Naylor, Stuart, Forbes, Alexandria, Lane, Amelia, Georgiadis, Anastasios
Published in International journal of molecular sciences (01.02.2024)
Published in International journal of molecular sciences (01.02.2024)
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Journal Article
Letter to the editor: 'Emerging gene therapy products for RPGR -associated X-linked retinitis pigmentosa'
Georgiadis, Anastasios, Smith, Alexander J, Michaelides, Michel, Naylor, Stuart, Forbes, Alexandria
Published in Expert opinion on emerging drugs (02.10.2022)
Published in Expert opinion on emerging drugs (02.10.2022)
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Journal Article
Spontaneous abortion is associated with differentially expressed angiogenic chemokines in placenta and decidua
Spathakis, Michail, Filidou, Eirini, Pappa, Chrysoula, Arzou, Bourazan Chalil, Georgiadis, Anastasios, Kontomanolis, Emmanuel N., Nikolettos, Nikos, Kolios, George, Galazios, George, Arvanitidis, Konstantinos
Published in Archives of gynecology and obstetrics (01.09.2023)
Published in Archives of gynecology and obstetrics (01.09.2023)
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First-in-Human Gene Therapy Trial of AAV8-hCARp.hCNGB3 in Adults and Children With CNGB3-associated Achromatopsia
Michaelides, Michel, Hirji, Nashila, Wong, Sui Chien, Besirli, Cagri G., Zaman, Serena, Kumaran, Neruban, Georgiadis, Anastasios, Smith, Alexander J., Ripamonti, Caterina, Gottlob, Irene, Robson, Anthony G., Thiadens, Alberta, Henderson, Robert H., Fleck, Penny, Anglade, Eddy, Dong, Xiangwen, Capuano, George, Lu, Wentao, Berry, Pamela, Kane, Thomas, Naylor, Stuart, Georgiou, Michalis, Kalitzeos, Angelos, Ali, Robin R., Forbes, Alexandria, Bainbridge, James
Published in American journal of ophthalmology (01.09.2023)
Published in American journal of ophthalmology (01.09.2023)
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Journal Article
Spatiotemporal control of actomyosin contractility by MRCKβ signaling drives phagocytosis
Zihni, Ceniz, Georgiadis, Anastasios, Ramsden, Conor M., Sanchez-Heras, Elena, Haas, Alexis J., Nommiste, Britta, Semenyuk, Olha, Bainbridge, James W.B., Coffey, Peter J., Smith, Alexander J., Ali, Robin R., Balda, Maria S., Matter, Karl
Published in The Journal of cell biology (07.11.2022)
Published in The Journal of cell biology (07.11.2022)
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