Misframed ubiquitin and impaired protein quality control: an early event in Alzheimer's disease
Gentier, Romina J, van Leeuwen, Fred W
Published in Frontiers in molecular neuroscience (02.09.2015)
Published in Frontiers in molecular neuroscience (02.09.2015)
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Mutant ubiquitin decreases amyloid β plaque formation in a transgenic mouse model of Alzheimer’s disease
van Tijn, Paula, Dennissen, Frank J.A., Gentier, Romina J.G., Hobo, Barbara, Hermes, Denise, Steinbusch, Harry W.M., Van Leeuwen, Fred W., Fischer, David F.
Published in Neurochemistry international (01.10.2012)
Published in Neurochemistry international (01.10.2012)
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Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast
Braun, Ralf J, Sommer, Cornelia, Leibiger, Christine, Gentier, Romina J, Dumit, Verónica I, Paduch, Katrin, Eisenberg, Tobias, Habernig, Lukas, Trausinger, Gert, Magnes, Christoph, Pieber, Thomas, Sinner, Frank, Dengjel, Jörn, Leeuwen, Fred W V, Kroemer, Guido, Madeo, Frank
Published in Microbial cell (20.03.2015)
Published in Microbial cell (20.03.2015)
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Paradoxical effects of mutant ubiquitin on Aβ plaque formation in an Alzheimer mouse model
Verheijen, Bert M., Stevens, Jo A.A., Gentier, Romina J.G., van ‘t Hekke, Christian D., van den Hove, Daniel L.A., Hermes, Denise J.H.P., Steinbusch, Harry W.M., Ruijter, Jan M., Grimm, Marcus O.W., Haupenthal, Viola J., Annaert, Wim, Hartmann, Tobias, van Leeuwen, Fred W.
Published in Neurobiology of aging (01.12.2018)
Published in Neurobiology of aging (01.12.2018)
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Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin
Braun, Ralf J., Sommer, Cornelia, Leibiger, Christine, Gentier, Romina J.G., Dumit, Verónica I., Paduch, Katrin, Eisenberg, Tobias, Habernig, Lukas, Trausinger, Gert, Magnes, Christoph, Pieber, Thomas, Sinner, Frank, Dengjel, Jörn, van Leeuwen, Fred W., Kroemer, Guido, Madeo, Frank
Published in Cell reports (Cambridge) (10.03.2015)
Published in Cell reports (Cambridge) (10.03.2015)
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Localization of mutant ubiquitin in the brain of a transgenic mouse line with proteasomal inhibition and its validation at specific sites in Alzheimer's disease
Gentier, Romina J G, Verheijen, Bert M, Zamboni, Margherita, Stroeken, Maartje M A, Hermes, Denise J H P, Küsters, Benno, Steinbusch, Harry W M, Hopkins, David A, Van Leeuwen, Fred W
Published in Frontiers in neuroanatomy (17.03.2015)
Published in Frontiers in neuroanatomy (17.03.2015)
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Long-term proteasomal inhibition in transgenic mice by UBB+1 expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients
Irmler, Martin, Gentier, Romina J. G., Dennissen, Frank J. A., Schulz, Holger, Bolle, Ines, Hölter, Sabine M., Kallnik, Magdalena, Cheng, Jing Jun, Klingenspor, Martin, Rozman, Jan, Ehrhardt, Nicole, Hermes, Denise J. H. P., Gailus-Durner, Valérie, Fuchs, Helmut, Hrabě de Angelis, Martin, Meyer, Helmut E., Hopkins, David A., Van Leeuwen, Fred W., Beckers, Johannes
Published in Acta neuropathologica (01.08.2012)
Published in Acta neuropathologica (01.08.2012)
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Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients
Irmler, Martin, Gentier, Romina J G, Dennissen, Frank J A, Schulz, Holger, Bolle, Ines, Hölter, Sabine M, Kallnik, Magdalena, Cheng, Jing Jun, Klingenspor, Martin, Rozman, Jan, Ehrhardt, Nicole, Hermes, Denise J H P, Gailus-Durner, Valérie, Fuchs, Helmut, Hrabě de Angelis, Martin, Meyer, Helmut E, Hopkins, David A, Van Leeuwen, Fred W, Beckers, Johannes
Published in Acta neuropathologica (01.08.2012)
Published in Acta neuropathologica (01.08.2012)
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Long-term proteasomal inhibition in transgenic mice by UBB^sup +1^ expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients
Irmler, Martin, Gentier, Romina J; G, Dennissen, Frank J; A, Schulz, Holger, Bolle, Ines, Hölter, Sabine M, Kallnik, Magdalena, Cheng, Jing Jun, Klingenspor, Martin, Rozman, Jan, Ehrhardt, Nicole, Hermes, Denise J; H; P, Gailus-durner, Valérie, Fuchs, Helmut, Hrab De Angelis, Martin, Meyer, Helmut E, Hopkins, David A, Van Leeuwen, Fred W, Beckers, Johannes
Published in Acta neuropathologica (01.08.2012)
Published in Acta neuropathologica (01.08.2012)
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Journal Article
Mutant ubiquitin decreases amyloid [beta] plaque formation in a transgenic mouse model of Alzheimer's disease
van Tijn, Paula, Dennissen, Frank JA, Gentier, Romina JG, Hobo, Barbara, Hermes, Denise, Steinbusch, Harry WM, Van Leeuwen, Fred W, Fischer, David F
Published in Neurochemistry international (01.10.2012)
Published in Neurochemistry international (01.10.2012)
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Journal Article
Long-term proteasomal inhibition in transgenic mice by UBB super(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients
Irmler, Martin, Gentier, Romina JG, Dennissen, Frank JA, Schulz, Holger, Bolle, Ines, Holter, Sabine M, Kallnik, Magdalena, Cheng, Jing Jun, Klingenspor, Martin, Rozman, Jan, Ehrhardt, Nicole, Hermes, Denise JHP, Gailus-Durner, Valerie, Fuchs, Helmut, Hrab de Angelis, Martin, Meyer, Helmut E, Hopkins, David A, Leeuwen, Fred W, Beckers, Johannes
Published in Acta neuropathologica (01.08.2012)
Published in Acta neuropathologica (01.08.2012)
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Journal Article