A subgroup of microRNAs defines PTEN-deficient, triple-negative breast cancer patients with poorest prognosis and alterations in RB1, MYC, and Wnt signaling
Wang, Dong-Yu, Gendoo, Deena M A, Ben-David, Yaacov, Woodgett, James R, Zacksenhaus, Eldad
Published in Breast cancer research : BCR (31.01.2019)
Published in Breast cancer research : BCR (31.01.2019)
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Journal Article
Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins
van Leeuwen, Jenna E., Ba-Alawi, Wail, Branchard, Emily, Cruickshank, Jennifer, Schormann, Wiebke, Longo, Joseph, Silvester, Jennifer, Gross, Peter L., Andrews, David W., Cescon, David W., Haibe-Kains, Benjamin, Penn, Linda Z., Gendoo, Deena M. A.
Published in Nature communications (24.10.2022)
Published in Nature communications (24.10.2022)
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Journal Article
Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer
Gendoo, Deena M A, Denroche, Robert E, Zhang, Amy, Radulovich, Nikolina, Jang, Gun Ho, Lemire, Mathieu, Fischer, Sandra, Chadwick, Dianne, Lungu, Ilinca M, Ibrahimov, Emin, Cao, Ping-Jiang, Stein, Lincoln D, Wilson, Julie M, Bartlett, John M S, Tsao, Ming-Sound, Dhani, Neesha, Hedley, David, Gallinger, Steven, Haibe-Kains, Benjamin
Published in PLoS computational biology (01.01.2019)
Published in PLoS computational biology (01.01.2019)
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Journal Article
Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy
Chung, Philip E. D., Gendoo, Deena M. A., Ghanbari-Azarnier, Ronak, Liu, Jeff C., Jiang, Zhe, Tsui, Jennifer, Wang, Dong-Yu, Xiao, Xiao, Li, Bryan, Dubuc, Adrian, Shih, David, Remke, Marc, Ho, Ben, Garzia, Livia, Ben-David, Yaacov, Kang, Seok-Gu, Croul, Sidney, Haibe-Kains, Benjamin, Huang, Annie, Taylor, Michael D., Zacksenhaus, Eldad
Published in Nature communications (14.04.2020)
Published in Nature communications (14.04.2020)
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Journal Article
Medulloblastoma subgroups remain stable across primary and metastatic compartments
Wang, Xin, Dubuc, Adrian M., Ramaswamy, Vijay, Mack, Stephen, Gendoo, Deena M. A., Remke, Marc, Wu, Xiaochong, Garzia, Livia, Luu, Betty, Cavalli, Florence, Peacock, John, López, Borja, Skowron, Patryk, Zagzag, David, Lyden, David, Hoffman, Caitlin, Cho, Yoon-Jae, Eberhart, Charles, MacDonald, Tobey, Li, Xiao-Nan, Van Meter, Timothy, Northcott, Paul A., Haibe-Kains, Benjamin, Hawkins, Cynthia, Rutka, James T., Bouffet, Eric, Pfister, Stefan M., Korshunov, Andrey, Taylor, Michael D.
Published in Acta neuropathologica (01.03.2015)
Published in Acta neuropathologica (01.03.2015)
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Journal Article
Integrative Cancer Pharmacogenomics to Infer Large-Scale Drug Taxonomy
El-Hachem, Nehme, Gendoo, Deena M A, Ghoraie, Laleh Soltan, Safikhani, Zhaleh, Smirnov, Petr, Chung, Christina, Deng, Kenan, Fang, Ailsa, Birkwood, Erin, Ho, Chantal, Isserlin, Ruth, Bader, Gary D, Goldenberg, Anna, Haibe-Kains, Benjamin
Published in Cancer research (Chicago, Ill.) (01.06.2017)
Published in Cancer research (Chicago, Ill.) (01.06.2017)
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Journal Article
Genefu: an R/Bioconductor package for computation of gene expression-based signatures in breast cancer
Gendoo, Deena M A, Ratanasirigulchai, Natchar, Schröder, Markus S, Paré, Laia, Parker, Joel S, Prat, Aleix, Haibe-Kains, Benjamin
Published in Bioinformatics (01.04.2016)
Published in Bioinformatics (01.04.2016)
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Journal Article
PrionHome: a database of prions and other sequences relevant to prion phenomena
Harbi, Djamel, Parthiban, Marimuthu, Gendoo, Deena M A, Ehsani, Sepehr, Kumar, Manish, Schmitt-Ulms, Gerold, Sowdhamini, Ramanathan, Harrison, Paul M
Published in PloS one (20.02.2012)
Published in PloS one (20.02.2012)
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Journal Article
PharmacoGx: an R package for analysis of large pharmacogenomic datasets
Smirnov, Petr, Safikhani, Zhaleh, El-Hachem, Nehme, Wang, Dong, She, Adrian, Olsen, Catharina, Freeman, Mark, Selby, Heather, Gendoo, Deena M A, Grossmann, Patrick, Beck, Andrew H, Aerts, Hugo J W L, Lupien, Mathieu, Goldenberg, Anna, Haibe-Kains, Benjamin
Published in Bioinformatics (15.04.2016)
Published in Bioinformatics (15.04.2016)
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Journal Article
Consensus on Molecular Subtypes of High-Grade Serous Ovarian Carcinoma
Chen, Gregory M, Kannan, Lavanya, Geistlinger, Ludwig, Kofia, Victor, Safikhani, Zhaleh, Gendoo, Deena M A, Parmigiani, Giovanni, Birrer, Michael, Haibe-Kains, Benjamin, Waldron, Levi
Published in Clinical cancer research (15.10.2018)
Published in Clinical cancer research (15.10.2018)
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Journal Article
Circulating tumour DNA detects somatic variants contributing to spatial and temporal intra-tumoural heterogeneity in head and neck squamous cell carcinoma
Payne, Karl F B, Brotherwood, Peter, Suriyanarayanan, Harini, Brooks, Jill M, Batis, Nikolaos, Beggs, Andrew D, Gendoo, Deena M A, Mehanna, Hisham, Nankivell, Paul
Published in Frontiers in oncology (23.04.2024)
Published in Frontiers in oncology (23.04.2024)
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Journal Article
Public data and open source tools for multi-assay genomic investigation of disease
Kannan, Lavanya, Ramos, Marcel, Re, Angela, El-Hachem, Nehme, Safikhani, Zhaleh, Gendoo, Deena M A, Davis, Sean, Gomez-Cabrero, David, Castelo, Robert, Hansen, Kasper D, Carey, Vincent J, Morgan, Martin, Culhane, Aedín C, Haibe-Kains, Benjamin, Waldron, Levi
Published in Briefings in bioinformatics (01.07.2016)
Published in Briefings in bioinformatics (01.07.2016)
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Journal Article
The molecular basis of breast cancer pathological phenotypes
Heng, Yujing J, Lester, Susan C, Tse, Gary MK, Factor, Rachel E, Allison, Kimberly H, Collins, Laura C, Chen, Yunn‐Yi, Jensen, Kristin C, Johnson, Nicole B, Jeong, Jong Cheol, Punjabi, Rahi, Shin, Sandra J, Singh, Kamaljeet, Krings, Gregor, Eberhard, David A, Tan, Puay Hoon, Korski, Konstanty, Waldman, Frederic M, Gutman, David A, Sanders, Melinda, Reis‐Filho, Jorge S, Flanagan, Sydney R, Gendoo, Deena MA, Chen, Gregory M, Haibe‐Kains, Benjamin, Ciriello, Giovanni, Hoadley, Katherine A, Perou, Charles M, Beck, Andrew H
Published in The Journal of pathology (01.02.2017)
Published in The Journal of pathology (01.02.2017)
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Journal Article
Administration of Hypoxia-Activated Prodrug Evofosfamide after Conventional Adjuvant Therapy Enhances Therapeutic Outcome and Targets Cancer-Initiating Cells in Preclinical Models of Colorectal Cancer
Haynes, Jennifer, McKee, Trevor D, Haller, Andrew, Wang, Yadong, Leung, Cherry, Gendoo, Deena M A, Lima-Fernandes, Evelyne, Kreso, Antonija, Wolman, Robin, Szentgyorgyi, Eva, Vines, Douglass C, Haibe-Kains, Benjamin, Wouters, Bradly G, Metser, Ur, Jaffray, David A, Smith, Myles, O'Brien, Catherine A
Published in Clinical cancer research (01.05.2018)
Published in Clinical cancer research (01.05.2018)
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Journal Article
CD73 is associated with poor prognosis in high-grade serous ovarian cancer
Turcotte, Martin, Spring, Kathleen, Pommey, Sandra, Chouinard, Guillaume, Cousineau, Isabelle, George, Joshy, Chen, Gregory M, Gendoo, Deena M A, Haibe-Kains, Benjamin, Karn, Thomas, Rahimi, Kurosh, Le Page, Cécile, Provencher, Diane, Mes-Masson, Anne-Marie, Stagg, John
Published in Cancer research (Chicago, Ill.) (01.11.2015)
Published in Cancer research (Chicago, Ill.) (01.11.2015)
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Journal Article
MM2S: personalized diagnosis of medulloblastoma patients and model systems
Gendoo, Deena M A, Haibe-Kains, Benjamin
Published in Source code for biology and medicine (11.04.2016)
Published in Source code for biology and medicine (11.04.2016)
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Journal Article