Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial System
Pattipeiluhu, Roy, Arias‐Alpizar, Gabriela, Basha, Genc, Chan, Karen Y. T., Bussmann, Jeroen, Sharp, Thomas H., Moradi, Mohammad‐Amin, Sommerdijk, Nico, Harris, Edward N., Cullis, Pieter R., Kros, Alexander, Witzigmann, Dominik, Campbell, Frederick
Published in Advanced materials (Weinheim) (01.04.2022)
Published in Advanced materials (Weinheim) (01.04.2022)
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Journal Article
Induction of Bleb Structures in Lipid Nanoparticle Formulations of mRNA Leads to Improved Transfection Potency
Cheng, Miffy Hok Yan, Leung, Jerry, Zhang, Yao, Strong, Colton, Basha, Genc, Momeni, Arash, Chen, Yihang, Jan, Eric, Abdolahzadeh, Amir, Wang, Xinying, Kulkarni, Jayesh A., Witzigmann, Dominik, Cullis, Pieter R.
Published in Advanced materials (Weinheim) (01.08.2023)
Published in Advanced materials (Weinheim) (01.08.2023)
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Journal Article
Lipid nanoparticle mRNA systems containing high levels of sphingomyelin engender higher protein expression in hepatic and extra-hepatic tissues
Chander, Nisha, Basha, Genc, Yan Cheng, Miffy Hok, Witzigmann, Dominik, Cullis, Pieter R.
Published in Molecular therapy. Methods & clinical development (14.09.2023)
Published in Molecular therapy. Methods & clinical development (14.09.2023)
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Journal Article
Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells
Basha, Genc, Novobrantseva, Tatiana I, Rosin, Nicole, Tam, Yuen Yi C, Hafez, Ismail M, Wong, Matthew K, Sugo, Tsukasa, Ruda, Vera M, Qin, June, Klebanov, Boris, Ciufolini, Marco, Akinc, Akin, Tam, Ying K, Hope, Michael J, Cullis, Pieter R
Published in Molecular therapy (01.12.2011)
Published in Molecular therapy (01.12.2011)
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Journal Article
Lipid Nanoparticle Delivery of siRNA to Osteocytes Leads to Effective Silencing of SOST and Inhibition of Sclerostin In Vivo
Basha, Genc, Ordobadi, Mina, Scott, Wilder R, Cottle, Andrew, Liu, Yan, Wang, Haitang, Cullis, Pieter R
Published in Molecular therapy. Nucleic acids (13.09.2016)
Published in Molecular therapy. Nucleic acids (13.09.2016)
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Journal Article
Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells
Novobrantseva, Tatiana I, Borodovsky, Anna, Wong, Jamie, Klebanov, Boris, Zafari, Mohammad, Yucius, Kristina, Querbes, William, Ge, Pei, Ruda, Vera M, Milstein, Stuart, Speciner, Lauren, Duncan, Rick, Barros, Scott, Basha, Genc, Cullis, Pieter, Akinc, Akin, Donahoe, Jessica S, Narayanannair Jayaprakash, K, Jayaraman, Muthusamy, Bogorad, Roman L, Love, Kevin, Whitehead, Katie, Levins, Chris, Manoharan, Muthiah, Swirski, Filip K, Weissleder, Ralph, Langer, Robert, Anderson, Daniel G, de Fougerolles, Antonin, Nahrendorf, Matthias, Koteliansky, Victor
Published in Molecular therapy. Nucleic acids (01.01.2012)
Published in Molecular therapy. Nucleic acids (01.01.2012)
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Journal Article
Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain
Tian, Meimei, Biron, Kaan E, Julien, Jean-Pierre, Basha, Genc, Lizée, Gregory, Jefferies, Wilfred A, Tiong, Jacqueline
Published in Nature immunology (01.11.2003)
Published in Nature immunology (01.11.2003)
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Journal Article
Dendritic cell cross-priming is essential for immune responses to Listeria monocytogenes
Reinicke, Anna T, Omilusik, Kyla D, Basha, Genc, Jefferies, Wilfred A
Published in PloS one (06.10.2009)
Published in PloS one (06.10.2009)
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Journal Article
Combining the Antigen Processing Components TAP and Tapasin Elicits Enhanced Tumor-Free Survival
Lou, Yuanmei, Basha, Genc, Seipp, Robyn P, Cai, Bing, Chen, Susan S, Moise, Alexander R, Jeffries, Andrew P, Gopaul, Ray S, Vitalis, Timothy Z, Jefferies, Wilfred A
Published in Clinical cancer research (01.03.2008)
Published in Clinical cancer research (01.03.2008)
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Journal Article
A CD74-dependent MHC class I endolysosomal cross-presentation pathway
Basha, Genc, Omilusik, Kyla, Chavez-Steenbock, Ana, Reinicke, Anna T, Lack, Nathan, Choi, Kyung Bok, Jefferies, Wilfred A
Published in Nature immunology (01.03.2012)
Published in Nature immunology (01.03.2012)
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Journal Article
Lipid nanoparticle-mediated silencing of osteogenic suppressor GNAS leads to osteogenic differentiation of mesenchymal stem cells in vivo
Basha, Genc, Cottle, Andrew G., Pretheeban, Thavaneetharajah, Chan, Karen YT, Witzigmann, Dominik, Young, Robert N., Rossi, Fabio MV, Cullis, Pieter R.
Published in Molecular therapy (07.09.2022)
Published in Molecular therapy (07.09.2022)
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Journal Article
A luciferase reporter mouse model to optimize in vivo gene editing validated by lipid nanoparticle delivery of adenine base editors
Yu, Si-Yue, Carlaw, Tiffany, Thomson, Tyler, Birkenshaw, Alexandra, Basha, Genc, Kurek, Daniel, Huang, Cassie, Kulkarni, Jayesh, Zhang, Lin-Hua, Ross, Colin J.D.
Published in Molecular therapy (05.04.2023)
Published in Molecular therapy (05.04.2023)
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Journal Article
The immunostimulatory activity of unmethylated and methylated CpG oligodeoxynucleotide is dependent on their ability to colocalize with TLR9 in late endosomes
de Jong, Susan D, Basha, Genc, Wilson, Kaley D, Kazem, Mikameh, Cullis, Pieter, Jefferies, Wilf, Tam, Ying
Published in The Journal of immunology (1950) (01.06.2010)
Published in The Journal of immunology (1950) (01.06.2010)
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Journal Article
Restoration of the expression of transporters associated with antigen processing in lung carcinoma increases tumor-specific immune responses and survival
YUANMEI LOU, VITALIS, Timothy Z, JEFFERIES, Wilfred A, BASHA, Genc, BING CAI, CHEN, Susan S, KYUNG BOK CHOI, JEFFRIES, Andrew P, ELLIOTT, W. Mark, ATKINS, Derek, SELIGER, Barbara
Published in Cancer research (Chicago, Ill.) (01.09.2005)
Published in Cancer research (Chicago, Ill.) (01.09.2005)
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Journal Article
LIPID NANOPARTICLES WITH BLEBS HAVING IMPROVED TRANSFECTION POTENCY
CULLIS, Pieter R, BASHA, Genc, LEUNG, Jerry, KULKARNI, Jayesh A, CHENG, Miffy Yok Han, WITZIGMANN, Dominik
Year of Publication 10.05.2024
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Year of Publication 10.05.2024
Patent
MRNA DELIVERY USING LIPID NANOPARTICLES
CULLIS, Pieter R, BASHA, Genc, CIUFOLINI, Marco A, KULKARNI, Jayesh A, CHANDER, Nisha, WITZIGMANN, Dominik
Year of Publication 10.04.2024
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Year of Publication 10.04.2024
Patent
Using the TAP component of the antigen-processing machinery as a molecular adjuvant
Vitalis, Timothy Z, Zhang, Qian-Jin, Alimonti, Judie, Chen, Susan S, Basha, Genc, Moise, Alex, Tiong, Jacqueline, Tian, Mei Mei, Choi, Kyung Bok, Waterfield, Douglas, Jeffries, Andy, Jefferies, Wilfred A
Published in PLoS pathogens (01.12.2005)
Published in PLoS pathogens (01.12.2005)
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