Foldamer-templated catalysis of macrocycle formation
Girvin, Zebediah C, Andrews, Mary Katherine, Liu, Xinyu, Gellman, Samuel H
Published in Science (American Association for the Advancement of Science) (20.12.2019)
Published in Science (American Association for the Advancement of Science) (20.12.2019)
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Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold
Andrews, Mary Katherine, Liu, Xinyu, Gellman, Samuel H
Published in Journal of the American Chemical Society (09.02.2022)
Published in Journal of the American Chemical Society (09.02.2022)
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Modulation of hydrophobic interactions by proximally immobilized ions
Ma, C. Derek, Wang, Chenxuan, Acevedo-Vélez, Claribel, Gellman, Samuel H., Abbott, Nicholas L.
Published in Nature (London) (15.01.2015)
Published in Nature (London) (15.01.2015)
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Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets
de Vries, Rory D, Schmitz, Katharina S, Bovier, Francesca T, Predella, Camilla, Khao, Jonathan, Noack, Danny, Haagmans, Bart L, Herfst, Sander, Stearns, Kyle N, Drew-Bear, Jennifer, Biswas, Sudipta, Rockx, Barry, McGill, Gaël, Dorrello, N Valerio, Gellman, Samuel H, Alabi, Christopher A, de Swart, Rik L, Moscona, Anne, Porotto, Matteo
Published in Science (26.03.2021)
Published in Science (26.03.2021)
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Nylon‑3 Polymers Active against Drug-Resistant Candida albicans Biofilms
Liu, Runhui, Chen, Xinyu, Falk, Shaun P, Masters, Kristyn S, Weisblum, Bernard, Gellman, Samuel H
Published in Journal of the American Chemical Society (18.02.2015)
Published in Journal of the American Chemical Society (18.02.2015)
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Crystal structure of the β2 adrenergic receptor–Gs protein complex
Rasmussen, Søren G. F., DeVree, Brian T., Zou, Yaozhong, Kruse, Andrew C., Chung, Ka Young, Kobilka, Tong Sun, Thian, Foon Sun, Chae, Pil Seok, Pardon, Els, Calinski, Diane, Mathiesen, Jesper M., Shah, Syed T. A., Lyons, Joseph A., Caffrey, Martin, Gellman, Samuel H., Steyaert, Jan, Skiniotis, Georgios, Weis, William I., Sunahara, Roger K., Kobilka, Brian K.
Published in Nature (London) (19.07.2011)
Published in Nature (London) (19.07.2011)
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Structure of a nanobody-stabilized active state of the β2 adrenoceptor
Rasmussen, Søren G. F., Choi, Hee-Jung, Fung, Juan Jose, Pardon, Els, Casarosa, Paola, Chae, Pil Seok, DeVree, Brian T., Rosenbaum, Daniel M., Thian, Foon Sun, Kobilka, Tong Sun, Schnapp, Andreas, Konetzki, Ingo, Sunahara, Roger K., Gellman, Samuel H., Pautsch, Alexander, Steyaert, Jan, Weis, William I., Kobilka, Brian K.
Published in Nature (London) (13.01.2011)
Published in Nature (London) (13.01.2011)
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Backbone modification of a polypeptide drug alters duration of action in vivo
Cheloha, Ross W, Maeda, Akira, Dean, Thomas, Gardella, Thomas J, Gellman, Samuel H
Published in Nature biotechnology (01.07.2014)
Published in Nature biotechnology (01.07.2014)
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Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon‑3 Polymers
Liu, Lei, Courtney, Kevin C, Huth, Sean W, Rank, Leslie A, Weisblum, Bernard, Chapman, Edwin R, Gellman, Samuel H
Published in Journal of the American Chemical Society (03.03.2021)
Published in Journal of the American Chemical Society (03.03.2021)
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Structure and function of an irreversible agonist-β2 adrenoceptor complex
Rosenbaum, Daniel M., Zhang, Cheng, Lyons, Joseph A., Holl, Ralph, Aragao, David, Arlow, Daniel H., Rasmussen, Søren G. F., Choi, Hee-Jung, DeVree, Brian T., Sunahara, Roger K., Chae, Pil Seok, Gellman, Samuel H., Dror, Ron O., Shaw, David E., Weis, William I., Caffrey, Martin, Gmeiner, Peter, Kobilka, Brian K.
Published in Nature (London) (13.01.2011)
Published in Nature (London) (13.01.2011)
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Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR
White, Alex D., Jean-Alphonse, Frederic G., Fang, Fei, Peña, Karina A., Liu, Shi, König, Gabriele M., Inoue, Asuka, Aslanoglou, Despoina, Gellman, Samuel H., Kostenis, Evi, Xiao, Kunhong, Vilardaga, Jean-Pierre
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2020)
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Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold
Checco, James W., Kreitler, Dale F., Thomas, Nicole C., Belair, David G., Rettko, Nicholas J., Murphy, William L., Forest, Katrina T., Gellman, Samuel H.
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2015)
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Mimicry of Antimicrobial Host-Defense Peptides by Random Copolymers
Mowery, Brendan P, Lee, Sarah E, Kissounko, Denis A, Epand, Raquel F, Epand, Richard M, Weisblum, Bernard, Stahl, Shannon S, Gellman, Samuel H
Published in Journal of the American Chemical Society (19.12.2007)
Published in Journal of the American Chemical Society (19.12.2007)
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Medium effects on minimum inhibitory concentrations of nylon-3 polymers against E. coli
Choi, Heejun, Chakraborty, Saswata, Liu, Runhui, Gellman, Samuel H, Weisshaar, James C
Published in PloS one (25.08.2014)
Published in PloS one (25.08.2014)
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Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers
Horne, W. Seth, Johnson, Lisa M, Ketas, Thomas J, Klasse, Per Johan, Lu, Min, Moore, John P, Gellman, Samuel H
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (01.09.2009)
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