Embracing proteins: structural themes in aptamer–protein complexes
Gelinas, Amy D, Davies, Douglas R, Janjic, Nebojsa
Published in Current opinion in structural biology (01.02.2016)
Published in Current opinion in structural biology (01.02.2016)
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Journal Article
Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents
Rohloff, John C, Gelinas, Amy D, Jarvis, Thale C, Ochsner, Urs A, Schneider, Daniel J, Gold, Larry, Janjic, Nebojsa
Published in Molecular therapy. Nucleic acids (01.10.2014)
Published in Molecular therapy. Nucleic acids (01.10.2014)
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Evolving A RIG-I Antagonist: A Modified DNA Aptamer Mimics Viral RNA
Ren, Xiaoming, Gelinas, Amy D., Linehan, Melissa, Iwasaki, Akiko, Wang, Wenshuai, Janjic, Nebojsa, Pyle, Anna Marie
Published in Journal of molecular biology (15.10.2021)
Published in Journal of molecular biology (15.10.2021)
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Journal Article
Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets
Davies, Douglas R, Gelinas, Amy D, Zhang, Chi, Rohloff, John C, Carter, Jeffrey D, O’Connell, Daniel, Waugh, Sheela M, Wolk, Steven K, Mayfield, Wesley S, Burgin, Alex B, Edwards, Thomas E, Stewart, Lance J, Gold, Larry, Janjic, Nebojsa, Jarvis, Thale C
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2012)
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Modified nucleotides may have enhanced early RNA catalysis
Wolk, Steven K., Mayfield, Wesley S., Gelinas, Amy D., Astling, David, Guillot, Jessica, Brody, Edward N., Janjic, Nebojsa, Gold, Larry
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2020)
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Journal Article
Crystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid Ligand
Gelinas, Amy D., Davies, Douglas R., Edwards, Thomas E., Rohloff, John C., Carter, Jeffrey D., Zhang, Chi, Gupta, Shashi, Ishikawa, Yuichi, Hirota, Masao, Nakaishi, Yuichiro, Jarvis, Thale C., Janjic, Nebojsa
Published in The Journal of biological chemistry (21.03.2014)
Published in The Journal of biological chemistry (21.03.2014)
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Journal Article
Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor
Jarvis, Thale C., Davies, Douglas R., Hisaminato, Akihiko, Resnicow, Daniel I., Gupta, Shashi, Waugh, Sheela M., Nagabukuro, Akira, Wadatsu, Takashi, Hishigaki, Haretsugu, Gawande, Bharat, Zhang, Chi, Wolk, Steven K., Mayfield, Wesley S., Nakaishi, Yuichiro, Burgin, Alex B., Stewart, Lance J., Edwards, Thomas E., Gelinas, Amy D., Schneider, Daniel J., Janjic, Nebojsa
Published in Structure (London) (07.07.2015)
Published in Structure (London) (07.07.2015)
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Journal Article
Broadly neutralizing aptamers to SARS-CoV-2: A diverse panel of modified DNA antiviral agents
Gelinas, Amy D., Tan, Tiong Kit, Liu, Sai, Jaramillo, Javier G., Chadwick, James, Harding, Adam C., Zhang, Chi, Ream, Brian E., Chase, Chelsea N., Otis, Matthew R., Lee, Thomas, Schneider, Daniel J., James, William S., Janjic, Nebojsa
Published in Molecular therapy. Nucleic acids (14.03.2023)
Published in Molecular therapy. Nucleic acids (14.03.2023)
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Journal Article
Modified aptamers as reagents to characterize recombinant human erythropoietin products
Jankowski, Wojciech, Lagassé, H. A. Daniel, Chang, William C., McGill, Joseph, Jankowska, Katarzyna I., Gelinas, Amy D., Janjic, Nebojsa, Sauna, Zuben E.
Published in Scientific reports (29.10.2020)
Published in Scientific reports (29.10.2020)
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Journal Article
Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain
Gelinas, Amy D, Paschini, Margherita, Reyes, Francis E, Héroux, Annie, Batey, Robert T, Lundblad, Victoria, Wuttke, Deborah S
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2009)
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Journal Article
Thermodynamic Linkage in the GrpE Nucleotide Exchange Factor, a Molecular Thermosensor
Gelinas, Amy D, Toth, Joseph, Bethoney, Kelley A, Langsetmo, Knut, Stafford, Walter F, Harrison, Celia J
Published in Biochemistry (Easton) (05.08.2003)
Published in Biochemistry (Easton) (05.08.2003)
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A Structure-based Interpretation of E. coli GrpE Thermodynamic Properties
Gelinas, Amy D, Langsetmo, Knut, Toth, Joseph, Bethoney, Kelley A, Stafford, Walter F, Harrison, Celia J
Published in Journal of molecular biology (11.10.2002)
Published in Journal of molecular biology (11.10.2002)
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Journal Article
Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies
Alexaki, Aikaterini, Hettiarachchi, Gaya K., Athey, John C., Katneni, Upendra K., Simhadri, Vijaya, Hamasaki-Katagiri, Nobuko, Nanavaty, Puja, Lin, Brian, Takeda, Kazuyo, Freedberg, Darón, Monroe, Dougald, McGill, Joseph R., Peters, Robert, Kames, Jacob M., Holcomb, David D., Hunt, Ryan C., Sauna, Zuben E., Gelinas, Amy, Janjic, Nebojsa, DiCuccio, Michael, Bar, Haim, Komar, Anton A., Kimchi-Sarfaty, Chava
Published in Scientific reports (29.10.2019)
Published in Scientific reports (29.10.2019)
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Journal Article
Rapid histochemistry using slow off-rate modified aptamers with anionic competition
Gupta, Shashi, Thirstrup, Derek, Jarvis, Thale C, Schneider, Daniel J, Wilcox, Sheri K, Carter, Jeff, Zhang, Chi, Gelinas, Amy, Weiss, Allison, Janjic, Nebojsa, Baird, Geoffrey S
Published in Applied immunohistochemistry & molecular morphology (01.05.2011)
Published in Applied immunohistochemistry & molecular morphology (01.05.2011)
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