Harnessing human ADAR2 for RNA repair - Recoding a PINK1 mutation rescues mitophagy
Wettengel, Jacqueline, Reautschnig, Philipp, Geisler, Sven, Kahle, Philipp J, Stafforst, Thorsten
Published in Nucleic acids research (17.03.2017)
Published in Nucleic acids research (17.03.2017)
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Journal Article
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Fiesel, Fabienne C, Geisler, Sven, Kahle, Philipp J, Springer, Wolfdieter, Skujat, Diana, Rothfuss, Oliver C, Holmström, Kira M
Published in Nature cell biology (01.02.2010)
Published in Nature cell biology (01.02.2010)
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Journal Article
VPS35 dysfunction impairs lysosomal degradation of α-synuclein and exacerbates neurotoxicity in a Drosophila model of Parkinson's disease
Miura, Emiko, Hasegawa, Takafumi, Konno, Masatoshi, Suzuki, Mari, Sugeno, Naoto, Fujikake, Nobuhiro, Geisler, Sven, Tabuchi, Mitsuaki, Oshima, Ryuji, Kikuchi, Akio, Baba, Toru, Wada, Keiji, Nagai, Yoshitaka, Takeda, Atsushi, Aoki, Masashi
Published in Neurobiology of disease (01.11.2014)
Published in Neurobiology of disease (01.11.2014)
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Journal Article
The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations
Geisler, Sven, Holmström, Kira M, Treis, Angela, Skujat, Diana, Weber, Stephanie S, Fiesel, Fabienne C, Kahle, Philipp J, Springer, Wolfdieter
Published in Autophagy (01.10.2010)
Published in Autophagy (01.10.2010)
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Journal Article
Hyperglycemia Impairs Proteasome Function by Methylglyoxal
QUEISSER, Markus A, DACHUN YAO, GEISLER, Sven, HAMMES, Hans-Peter, LOCHNIT, Günter, SCHLEICHER, Erwin D, BROWNLEE, Michael, PREISSNER, Klaus T
Published in Diabetes (New York, N.Y.) (01.03.2010)
Published in Diabetes (New York, N.Y.) (01.03.2010)
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Journal Article
UBE2E Ubiquitin-conjugating Enzymes and Ubiquitin Isopeptidase Y Regulate TDP-43 Protein Ubiquitination
Hans, Friederike, Fiesel, Fabienne C., Strong, Jennifer C., Jäckel, Sandra, Rasse, Tobias M., Geisler, Sven, Springer, Wolfdieter, Schulz, Jörg B., Voigt, Aaron, Kahle, Philipp J.
Published in The Journal of biological chemistry (04.07.2014)
Published in The Journal of biological chemistry (04.07.2014)
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Journal Article
UBE2N, UBE2L3 and UBE2D2/3 ubiquitin-conjugating enzymes are essential for parkin-dependent mitophagy
Geisler, Sven, Vollmer, Stefanie, Golombek, Sonia, Kahle, Philipp J.
Published in Journal of cell science (01.01.2014)
Published in Journal of cell science (01.01.2014)
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Journal Article
Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors
Bus, Christine, Zizmare, Laimdota, Feldkaemper, Marita, Geisler, Sven, Zarani, Maria, Schaedler, Anna, Klose, Franziska, Admard, Jakob, Mageean, Craig J., Arena, Giuseppe, Fallier-Becker, Petra, Ugun-Klusek, Aslihan, Maruszczak, Klaudia K., Kapolou, Konstantina, Schmid, Benjamin, Rapaport, Doron, Ueffing, Marius, Casadei, Nicolas, Krüger, Rejko, Gasser, Thomas, Vogt Weisenhorn, Daniela M., Kahle, Philipp J., Trautwein, Christoph, Gloeckner, Christian J., Fitzgerald, Julia C.
Published in iScience (18.12.2020)
Published in iScience (18.12.2020)
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Journal Article
Ubiquitin-specific protease USP36 knockdown impairs Parkin-dependent mitophagy via downregulation of Beclin-1-associated autophagy-related ATG14L
Geisler, Sven, Jäger, Lea, Golombek, Sonia, Nakanishi, Etsuro, Hans, Friederike, Casadei, Nicolas, Terradas, Anna Lechado, Linnemann, Caren, Kahle, Philipp J.
Published in Experimental cell research (15.11.2019)
Published in Experimental cell research (15.11.2019)
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Journal Article
Synthetic niche to modulate regenerative potential of MSCs and enhance skeletal muscle regeneration
Pumberger, Matthias, Qazi, Taimoor H, Ehrentraut, M. Christine, Textor, Martin, Kueper, Janina, Stoltenburg-Didinger, Gisela, Winkler, Tobias, von Roth, Philipp, Reinke, Simon, Borselli, Cristina, Perka, Carsten, Mooney, David J, Duda, Georg N, Geißler, Sven
Published in Biomaterials (01.08.2016)
Published in Biomaterials (01.08.2016)
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Journal Article
Activated Platelets Upregulate β2 Integrin Mac-1 (CD11b/CD18) on Dendritic Cells, Which Mediates Heterotypic Cell–Cell Interaction
Nording, Henry, Sauter, Manuela, Lin, Chaolan, Steubing, Rebecca, Geisler, Sven, Sun, Ying, Niethammer, Joel, Emschermann, Fréderic, Wang, Yunmei, Zieger, Barbara, Nieswandt, Bernhard, Kleinschnitz, Christoph, Simon, Daniel I., Langer, Harald F.
Published in The Journal of immunology (1950) (01.04.2022)
Published in The Journal of immunology (1950) (01.04.2022)
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Journal Article
Lys-63-linked Ubiquitination by E3 Ubiquitin Ligase Nedd4-1 Facilitates Endosomal Sequestration of Internalized α-Synuclein
Sugeno, Naoto, Hasegawa, Takafumi, Tanaka, Nobuyuki, Fukuda, Mitsunori, Wakabayashi, Koichi, Oshima, Ryuji, Konno, Masashi, Miura, Emiko, Kikuchi, Akio, Baba, Toru, Anan, Tadashi, Nakao, Mitsuyoshi, Geisler, Sven, Aoki, Masashi, Takeda, Atsushi
Published in The Journal of biological chemistry (27.06.2014)
Published in The Journal of biological chemistry (27.06.2014)
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Journal Article
Activated Platelets Upregulate β 2 Integrin Mac-1 (CD11b/CD18) on Dendritic Cells, Which Mediates Heterotypic Cell-Cell Interaction
Nording, Henry, Sauter, Manuela, Lin, Chaolan, Steubing, Rebecca, Geisler, Sven, Sun, Ying, Niethammer, Joel, Emschermann, Fréderic, Wang, Yunmei, Zieger, Barbara, Nieswandt, Bernhard, Kleinschnitz, Christoph, Simon, Daniel I, Langer, Harald F
Published in The Journal of immunology (1950) (01.04.2022)
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Published in The Journal of immunology (1950) (01.04.2022)
Journal Article
Physical and functional interactions between Escherichia coli MutL and the Vsr repair endonuclease
Heinze, Roger J, Giron-Monzon, Luis, Solovyova, Alexandra, Elliot, Sarah L, Geisler, Sven, Cupples, Claire G, Connolly, Bernard A, Friedhoff, Peter
Published in Nucleic acids research (01.07.2009)
Published in Nucleic acids research (01.07.2009)
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Journal Article
PINKl/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Geisler, Sven, Holmstrom, Kira M, Skujat, Diana, Fiesel, Fabienne C, Rothfuss, Oliver C, Kahle, Philipp J, Springer, Wolfdieter
Published in Nature cell biology (01.02.2010)
Published in Nature cell biology (01.02.2010)
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Journal Article
PINK1 Regulates Dopamine and Lipids at Mitochondria to Maintain Synapses and Neuronal Function
Bus, Christine, Geisler, Sven, Feldkaemper, Marita, Flores-Romero, Hector, Schaedler, Anna, Zittlau, Katharina, Zarini, Maria, Uysal, Betuel, Casadei, Nicolas, Fallier-Becker, Petra, Schwarz, Lisa, Brouwers, Jos F, Koch, Henner, Ugun-Klusek, Aslihan, Maruszczak, Klaudia, Vogt-Weisenhorn, Daniela, Wurst, Wolfgang, Schmidt, Benjamin, Martens, Gerard J, Bruegger, Britta, Rapaport, Doron, Garcia-Saez, Ana J, Macek, Boris, Krueger, Rejko, Gasser, Thomas, Kahle, Philipp J, Fitzgerald, Julia Catherine
Published in bioRxiv (22.10.2019)
Published in bioRxiv (22.10.2019)
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