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Multi-Center Randomized Phase II Study Comparing Cediranib plus Gefitinib with Cediranib plus Placebo in Subjects with Recurrent/Progressive Glioblastoma
Brown, Nicholas, McBain, Catherine, Nash, Stephen, Hopkins, Kirsten, Sanghera, Paul, Saran, Frank, Phillips, Mark, Dungey, Fiona, Clifton-Hadley, Laura, Wanek, Katharina, Krell, Daniel, Jeffries, Sarah, Khan, Iftekhar, Smith, Paul, Mulholland, Paul
Published in PloS one (27.05.2016)
Published in PloS one (27.05.2016)
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Rhabdomyolysis Caused by Gefitinib Overdose
Obayashi, Shohei, Tomomatsu, Katsuyoshi, Urata, Mika, Tanaka, Jun, Niimi, Kyoko, Hayama, Naoki, Oguma, Tsuyoshi, Asano, Koichiro, Ito, Yoko
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Published in Internal Medicine (15.05.2022)
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Association of Variability and Pharmacogenomics With Bioequivalence of Gefitinib in Healthy Male Subjects
Zhang, Hong, Li, Qingmei, Zhu, Xiaoxue, Wu, Min, Li, Cuiyun, Li, Xiaojiao, Liu, Chengjiao, Shen, Zhenwei, Ding, Yanhua, Hua, Shucheng
Published in Frontiers in pharmacology (07.08.2018)
Published in Frontiers in pharmacology (07.08.2018)
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Determinants of gefitinib pharmacokinetics in healthy Chinese male subjects: A pharmacogenomic study of cytochrome p450 enzymes and transporters
Wan, Zirui, Guo, Lifang, Li, Pengfei, Zhao, Zhixia, Xu, Benshan, Ren, Lulu, Yan, Yan, Liu, He, Zhang, Yiwen, Liu, Lihong
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Published in Journal of clinical pharmacy and therapeutics (01.10.2020)
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Therapeutic effects of gefitinib-encapsulated thermosensitive injectable hydrogel in intervertebral disc degeneration
Pan, Zongyou, Sun, Heng, Xie, Binbin, Xia, Dongdong, Zhang, Xiaoan, Yu, Dongsheng, Li, Jun, Xu, Yuzi, Wang, Zuhua, Wu, Yan, Zhang, Xiaolei, Wang, Yafei, Fu, Qianbao, Hu, Wei, Yang, Yang, Bunpetch, Varitsara, Shen, Weiliang, Heng, Boon Chin, Zhang, Shufang, Ouyang, Hongwei
Published in Biomaterials (01.04.2018)
Published in Biomaterials (01.04.2018)
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570P A first-in-human phase I study of the AXL inhibitor DS-1205c in combination with gefitinib in subjects with EGFR-mutant NSCLC
Nishio, M., Okamoto, I., Murakami, H., Horinouchi, H., Toyozawa, R., Takeda, M., Uno, M., Crawford, N., Jimbo, T., Ishigami, M., Takayama, G., Nakayama, S., Ohwada, S., Slosberg, E., Goto, K.
Published in Annals of oncology (01.09.2020)
Published in Annals of oncology (01.09.2020)
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XL647—A Multitargeted Tyrosine Kinase Inhibitor: Results of a Phase II Study in Subjects with Non-small Cell Lung Cancer Who Have Progressed after Responding to Treatment with Either Gefitinib or Erlotinib
Pietanza, M. Catherine, Lynch, Thomas James, Lara, Primo N., Cho, John, Yanagihara, Ronald H., Vrindavanam, Nandagopal, Chowhan, Naveed Mahfooz, Gadgeel, Shirish M., Pennell, Nathan A., Funke, Roel, Mitchell, Ben, Wakelee, Heather A., Miller, Vincent A.
Published in Journal of thoracic oncology (01.01.2012)
Published in Journal of thoracic oncology (01.01.2012)
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Pharmacokinetics of gefitinib in humans: The influence of gastrointestinal factors
Bergman, Ebba, Forsell, Patrik, Persson, Eva M., Knutson, Lars, Dickinson, Paul, Smith, Robert, Swaisland, Helen, Farmer, Matthew R., Cantarini, Mireille V., Lennernäs, Hans
Published in International journal of pharmaceutics (16.08.2007)
Published in International journal of pharmaceutics (16.08.2007)
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Detection of pharmacolipidodynamic effects following the intravenous and oral administration of gefitinib to C57Bl/6JRj mice by rapid UHPLC-MS analysis of plasma
Plumb, Robert S., Gethings, Lee A., Isaac, Giorgis, Munjoma, Nyasha C., Wilson, Ian D.
Published in Scientific reports (24.07.2024)
Published in Scientific reports (24.07.2024)
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Clinical Impact of Gastric Acid-Suppressing Medication Use on the Efficacy of Erlotinib and Gefitinib in Patients With Advanced Non–Small-Cell Lung Cancer Harboring EGFR Mutations
Zenke, Yoshitaka, Yoh, Kiyotaka, Matsumoto, Shingo, Umemura, Shigeki, Niho, Seiji, Ohmatsu, Hironobu, Goto, Koichi, Ohe, Yuichiro
Published in Clinical lung cancer (01.09.2016)
Published in Clinical lung cancer (01.09.2016)
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Gefitinib versus placebo as maintenance therapy in patients with locally advanced or metastatic non-small-cell lung cancer (INFORM; C-TONG 0804): a multicentre, double-blind randomised phase 3 trial
Zhang, Li, Ma, Shenglin, Song, Xiangqun, Han, Baohui, Cheng, Ying, Huang, Cheng, Yang, Shujun, Liu, Xiaoqing, Liu, Yunpeng, Lu, Shun, Wang, Jie, Zhang, Shucai, Zhou, Caicun, Zhang, Xiangwei, Hayashi, Nobuya, Wang, Mengzhao
Published in The lancet oncology (01.05.2012)
Published in The lancet oncology (01.05.2012)
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Rational application of gefitinib in NSCLC patients with sensitive EGFR mutations based on pharmacokinetics and metabolomics
Feng, Wei, Chen, Xi, Guan, Shao-xing, Ruan, Hong-lian, Huang, Yan, Zhang, Hui-zhen, Yang, Yun-peng, Fang, Wen-feng, Zhao, Hong-yun, Zhuang, Wei, Xin, Shuang, Chen, You-hao, Wang, Fei, Gao, Yue, Huang, Min, Wang, Xue-ding, Zhang, Li
Published in Acta pharmacologica Sinica (01.07.2022)
Published in Acta pharmacologica Sinica (01.07.2022)
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Rhabdomyolysis Caused by Gefitinib Overdose: A Case Report
Obayashi, Shohei, Tomomatsu, Katsuyoshi, Urata, Mika, Tanaka, Jun, Niimi, Kyoko, Hayama, Naoki, Oguma, Tsuyoshi, Asano, Koichiro, Ito, Yoko
Published in Internal Medicine (2022)
Published in Internal Medicine (2022)
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Prospective Study of Gefitinib Readministration After Chemotherapy in Patients With Advanced Non–Small-Cell Lung Cancer Who Previously Responded to Gefitinib
Koizumi, Tomonobu, Agatsuma, Toshihiko, Ikegami, Kayoko, Suzuki, Toshiro, Kobayashi, Takashi, Kanda, Shintaro, Yoshikawa, Sumiko, Kubo, Keishi, Shiina, Takayuki, Takasuna, Keiichirou, Matsuo, Akemi, Hayasaka, Muneharu, Morikawa, Miwa, Ameshima, Shingo
Published in Clinical lung cancer (01.11.2012)
Published in Clinical lung cancer (01.11.2012)
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A randomized trial of combination anastrozole plus gefitinib and of combination fulvestrant plus gefitinib in the treatment of postmenopausal women with hormone receptor positive metastatic breast cancer
Carlson, Robert W., O’Neill, Anne, Vidaurre, Tatiana, Gomez, Henry L., Badve, Sunil S., Sledge, George W.
Published in Breast cancer research and treatment (01.06.2012)
Published in Breast cancer research and treatment (01.06.2012)
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Phase 1 study of DS‐1205c combined with gefitinib for EGFR mutation‐positive non‐small cell lung cancer
Goto, Koichi, Shiraishi, Yoshimasa, Murakami, Haruyasu, Horinouchi, Hidehito, Toyozawa, Ryo, Takeda, Masayuki, Uno, Makiko, Crawford, Nigel, McGill, Joseph, Jimbo, Takeshi, Ishigami, Masato, Takayama, Gensuke, Nakayama, Shintaro, Ohwada, Shoichi, Nishio, Makoto
Published in Cancer medicine (Malden, MA) (01.03.2023)
Published in Cancer medicine (Malden, MA) (01.03.2023)
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P2.06-021 Efficacy and Safety of ASP8273 versus Erlotinib or Gefitinib as First-Line Treatment in Subjects with EGFRMut+ NSCLC
Kelly, Ronan, Horn, Leora, Chih-Hsin Yang, James, Lee, Dae Ho, Desai, Bhardwaj, Fleege, Tanya, Jie, Fei, Poondru, Srinivasu, Keating, Anne, Whitcomb, Debbie, Murase, Tosei, Uegaki, Koichi, Aoyama, Kouji, Nakagawa, Kazuhiko
Published in Journal of thoracic oncology (01.01.2017)
Published in Journal of thoracic oncology (01.01.2017)
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