Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity
Adams, Jarrett J, Narayanan, Samanthi, Birnbaum, Michael E, Sidhu, Sachdev S, Blevins, Sydney J, Gee, Marvin H, Sibener, Leah V, Baker, Brian M, Kranz, David M, Garcia, K Christopher
Published in Nature immunology (01.01.2016)
Published in Nature immunology (01.01.2016)
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Journal Article
Domain-swapped T cell receptors improve the safety of TCR gene therapy
Bethune, Michael T, Gee, Marvin H, Bunse, Mario, Lee, Mark S, Gschweng, Eric H, Pagadala, Meghana S, Zhou, Jing, Cheng, Donghui, Heath, James R, Kohn, Donald B, Kuhns, Michael S, Uckert, Wolfgang, Baltimore, David
Published in eLife (08.11.2016)
Published in eLife (08.11.2016)
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Journal Article
Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity
Mendoza, Juan L, Fischer, Suzanne, Gee, Marvin H, Lam, Lilian H, Brackenridge, Simon, Powrie, Fiona M, Birnbaum, Michael, McMichael, Andrew J, Garcia, K Christopher, Gillespie, Geraldine M
Published in eLife (27.07.2020)
Published in eLife (27.07.2020)
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Journal Article
Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells
Fraietta, Joseph A., Nobles, Christopher L., Sammons, Morgan A., Lundh, Stefan, Carty, Shannon A., Reich, Tyler J., Cogdill, Alexandria P., Morrissette, Jennifer J. D., DeNizio, Jamie E., Reddy, Shantan, Hwang, Young, Gohil, Mercy, Kulikovskaya, Irina, Nazimuddin, Farzana, Gupta, Minnal, Chen, Fang, Everett, John K., Alexander, Katherine A., Lin-Shiao, Enrique, Gee, Marvin H., Liu, Xiaojun, Young, Regina M., Ambrose, David, Wang, Yan, Xu, Jun, Jordan, Martha S., Marcucci, Katherine T., Levine, Bruce L., Garcia, K. Christopher, Zhao, Yangbing, Kalos, Michael, Porter, David L., Kohli, Rahul M., Lacey, Simon F., Berger, Shelley L., Bushman, Frederic D., June, Carl H., Melenhorst, J. Joseph
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
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Journal Article
Tuning T cell receptor sensitivity through catch bond engineering
Zhao, Xiang, Kolawole, Elizabeth M, Chan, Waipan, Feng, Yinnian, Yang, Xinbo, Gee, Marvin H, Jude, Kevin M, Sibener, Leah V, Fordyce, Polly M, Germain, Ronald N, Evavold, Brian D, Garcia, K Christopher
Published in Science (American Association for the Advancement of Science) (08.04.2022)
Published in Science (American Association for the Advancement of Science) (08.04.2022)
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Journal Article
Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding
Sibener, Leah V., Fernandes, Ricardo A., Kolawole, Elizabeth M., Carbone, Catherine B., Liu, Fan, McAffee, Darren, Birnbaum, Michael E., Yang, Xinbo, Su, Laura F., Yu, Wong, Dong, Shen, Gee, Marvin H., Jude, Kevin M., Davis, Mark M., Groves, Jay T., Goddard, William A., Heath, James R., Evavold, Brian D., Vale, Ronald D., Garcia, K. Christopher
Published in Cell (26.07.2018)
Published in Cell (26.07.2018)
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Journal Article
Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes
Gee, Marvin H., Han, Arnold, Lofgren, Shane M., Beausang, John F., Mendoza, Juan L., Birnbaum, Michael E., Bethune, Michael T., Fischer, Suzanne, Yang, Xinbo, Gomez-Eerland, Raquel, Bingham, David B., Sibener, Leah V., Fernandes, Ricardo A., Velasco, Andrew, Baltimore, David, Schumacher, Ton N., Khatri, Purvesh, Quake, Stephen R., Davis, Mark M., Garcia, K. Christopher
Published in Cell (25.01.2018)
Published in Cell (25.01.2018)
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Journal Article
T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability
Riley, Timothy P., Hellman, Lance M., Gee, Marvin H., Mendoza, Juan L., Alonso, Jesus A., Foley, Kendra C., Nishimura, Michael I., Vander Kooi, Craig W., Garcia, K. Christopher, Baker, Brian M.
Published in Nature chemical biology (01.10.2018)
Published in Nature chemical biology (01.10.2018)
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Journal Article
Computational and Systems Immunology: A Student’s Perspective
Good, Zinaida, Glanville, Jacob, Gee, Marvin H., Davis, Mark M., Khatri, Purvesh
Published in Trends in immunology (01.08.2019)
Published in Trends in immunology (01.08.2019)
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Journal Article
Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro
Gee, Marvin H., Sibener, Leah V., Birnbaum, Michael E., Jude, Kevin M., Yang, Xinbo, Fernandes, Ricardo A., Mendoza, Juan L., Glassman, Caleb R., Garcia, K. Christopher
Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2018)
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Journal Article
Identification of Antigenic Targets
Gerber, Hans-Peter, Sibener, Leah V, Lee, Luke J, Gee, Marvin H
Published in Trends in cancer (01.04.2020)
Published in Trends in cancer (01.04.2020)
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Journal Article
Isolation and visualization of a structural trigger that uncouples TCR signaling from pMHC binding
Sibener, Leah V., Fernandes, Ricardo A., Kolawole, Elizabeth M., Carbone, Catherine B., Liu, Fan, McAffee, Darren, Birnbaum, Michael E., Yang, Xinbo, Su, Laura F., Yu, Wong, Dong, Shen, Gee, Marvin H., Jude, Kevin M., Davis, Mark M., Groves, Jay T., Goddard, William A., Heath, James R., Evavold, Brian D., Vale, Ronald D., Garcia, K. Christopher
Published in Cell (26.07.2018)
Published in Cell (26.07.2018)
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Journal Article
Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding
Sibener, Leah V., Fernandes, Ricardo A., Kolawole, Elizabeth M., Carbone, Catherine B., Liu, Fan, McAffee, Darren, Birnbaum, Michael E., Yang, Xinbo, Su, Laura F., Yu, Wong, Dong, Shen, Gee, Marvin H., Jude, Kevin M., Davis, Mark M., Groves, Jay T., Goddard, III, William A., Heath, James R., Evavold, Brian D., Vale, Ronald D., Garcia, K. Christopher
Published in Cell (01.07.2018)
Published in Cell (01.07.2018)
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Journal Article
Abstract 578: A functional approach to identifying and engineering TCRs results in highly-potent and specific TCRs for TCR-T cell therapy
Leonard, John D., Ramirez, Alejandro, Romero, Jason, Kleiner, Jake, Dreux, Joanna, Hegde, Bindu, Xie, Bryan, Sharathchandra, Akshay, Katz, Nathan, DeAlmeida, Venita I., Gerber, Hans-Peter, Gee, Marvin H., Sibener, Leah V.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Structural interplay between germline and adaptive recognition determines TCR-peptide-MHC cross-reactivity
Adams, Jarrett J., Narayanan, Samanthi, Birnbaum, Michael E., Sidhu, Sachdev S., Blevins, Sydney J., Gee, Marvin H., Sibener, Leah V., Baker, Brian M., Kranz, David M., Garcia, K. Christopher
Published in Nature immunology (02.11.2015)
Published in Nature immunology (02.11.2015)
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