Primary proximal tubule hyperreabsorption and impaired tubular transport counterregulation determine glomerular hyperfiltration in diabetes: a modeling analysis
Hallow, K Melissa, Gebremichael, Yeshitila, Helmlinger, Gabriel, Vallon, Volker
Published in American journal of physiology. Renal physiology (01.05.2017)
Published in American journal of physiology. Renal physiology (01.05.2017)
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Journal Article
Quantitative Systems Toxicology (QST) Modeling of Drug-Induced Acute Proximal Tubule Epithelial Cell Injury and Associated Renal Hemodynamic Responses: PO0364
Gebremichael, Yeshitila, Hamzavi, Nader, Woodhead, Jeffrey L., Ermakov, Sergey, Howell, Brett A.
Published in Journal of the American Society of Nephrology (01.10.2021)
Published in Journal of the American Society of Nephrology (01.10.2021)
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Journal Article
Mechanistic Modeling of Kidney-Injury Molecule 1 (KIM-1) as a Biomarker for Cisplatin-Induced AKI: PO0411
Hamzavi, Nader, Gebremichael, Yeshitila, Woodhead, Jeffrey L., Ermakov, Sergey, Howell, Brett A.
Published in Journal of the American Society of Nephrology (01.10.2021)
Published in Journal of the American Society of Nephrology (01.10.2021)
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Journal Article
Multiscale Mathematical Model of Drug-Induced Proximal Tubule Injury: Linking Urinary Biomarkers to Epithelial Cell Injury and Renal Dysfunction
Gebremichael, Yeshitila, Lu, James, Shankaran, Harish, Helmlinger, Gabriel, Mettetal, Jerome, Hallow, K Melissa
Published in Toxicological sciences (01.03.2018)
Published in Toxicological sciences (01.03.2018)
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Journal Article
Quantitative Prediction of Cisplatin-Induced AKI Using RENAsym, a Mechanistic Quantitative Systems Toxicology Model, and Renal Proximal Tubule Epithelial Cell In Vitro Assays: PO0234
Gebremichael, Yeshitila, Hamzavi, Nader, Woodhead, Jeffrey L., Tallapaka, Shailendra, Siler, Scott Q., Howell, Brett A.
Published in Journal of the American Society of Nephrology (01.10.2020)
Published in Journal of the American Society of Nephrology (01.10.2020)
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Journal Article
Effects of molecular model, ionic strength, divalent ions, and hydrophobic interaction on human neurofilament conformation
Lee, Joonseong, Kim, Seonghoon, Chang, Rakwoo, Jayanthi, Lakshmi, Gebremichael, Yeshitila
Published in The Journal of chemical physics (07.01.2013)
Published in The Journal of chemical physics (07.01.2013)
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Journal Article
Benchmarking renin suppression and blood pressure reduction of direct renin inhibitor imarikiren through quantitative systems pharmacology modeling
Gebremichael, Yeshitila, Lahu, Gezim, Vakilynejad, Majid, Hallow, K. Melissa
Published in Journal of pharmacokinetics and pharmacodynamics (01.02.2019)
Published in Journal of pharmacokinetics and pharmacodynamics (01.02.2019)
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Journal Article
Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen
Eichenbaum, Gary, Yang, Kyunghee, Gebremichael, Yeshitila, Howell, Brett A., Murray, F. Jay, Jacobson-Kram, David, Jaeschke, Hartmut, Kuffner, Edwin, Gelotte, Cathy K., Lai, John C.K., Wikoff, Daniele, Atillasoy, Evren
Published in Regulatory toxicology and pharmacology (01.12.2020)
Published in Regulatory toxicology and pharmacology (01.12.2020)
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Journal Article
Structural Properties of Neurofilament Sidearms: Sequence-Based Modeling of Neurofilament Architecture
Chang, Rakwoo, Kwak, Yongkyu, Gebremichael, Yeshitila
Published in Journal of molecular biology (21.08.2009)
Published in Journal of molecular biology (21.08.2009)
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Journal Article
Neurofilament stoichiometry simulations during neurodegeneration suggest a remarkable self-sufficient and stable in vivo protein structure
Kim, Seonghoon, Chang, Rakwoo, Teunissen, Charlotte, Gebremichael, Yeshitila, Petzold, Axel
Published in Journal of the neurological sciences (15.08.2011)
Published in Journal of the neurological sciences (15.08.2011)
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Journal Article
A critical review of the acetaminophen preclinical carcinogenicity and tumor promotion data and their implications for its carcinogenic hazard potential
Murray, F. Jay, Monnot, Andrew D., Jacobson-Kram, David, Cohen, Samuel M., Hardisty, Jerry F., Bandara, Suren B., Kovochich, Michael, Deore, Milind, Pitchaiyan, Suresh Kumar, Gelotte, Cathy K., Lai, John C.K., Atillasoy, Evren, Hermanowski-Vosatka, Anne, Kuffner, Edwin, Unice, Kenneth M., Yang, Kyunghee, Gebremichael, Yeshitila, Howell, Brett A., Eichenbaum, Gary
Published in Regulatory toxicology and pharmacology (01.12.2020)
Published in Regulatory toxicology and pharmacology (01.12.2020)
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Journal Article
Conformational properties of interacting neurofilaments: Monte Carlo simulations of cylindrically grafted apposing neurofilament brushes
Jayanthi, Lakshmi, Stevenson, William, Kwak, Yongkyu, Chang, Rakwoo, Gebremichael, Yeshitila
Published in Journal of biological physics (01.06.2013)
Published in Journal of biological physics (01.06.2013)
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Journal Article
The Role of Phosphorylation on Mouse Neurofilament Medium Protein (NF-M) Sidearms
Stevenson, William, Chang, Rakwoo, Gebremichael, Yeshitila
Published in Biophysical journal (01.01.2010)
Published in Biophysical journal (01.01.2010)
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Journal Article
Expansion of neurofilament medium C terminus increases axonal diameter independent of increases in conduction velocity or myelin thickness
Barry, Devin M, Stevenson, William, Bober, Brian G, Wiese, Peter J, Dale, Jeffrey M, Barry, Garet S, Byers, Nathan S, Strope, Jonathan D, Chang, Rakwoo, Schulz, David J, Shah, Sameer, Calcutt, Nigel A, Gebremichael, Yeshitila, Garcia, Michael L
Published in The Journal of neuroscience (02.05.2012)
Published in The Journal of neuroscience (02.05.2012)
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Journal Article
Computational Investigation of the Mechanism Behind Sidearm-Mediated Neurofilament Interaction
Jayanthi, Lakshmi, Stevenson, William, Chang, Rakwoo, Gebremichael, Yeshitila
Published in Biophysical journal (01.02.2011)
Published in Biophysical journal (01.02.2011)
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Journal Article