The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing
De Maio, Federico A, Risso, Guillermo, Iglesias, Nestor G, Shah, Priya, Pozzi, Berta, Gebhard, Leopoldo G, Mammi, Pablo, Mancini, Estefania, Yanovsky, Marcelo J, Andino, Raul, Krogan, Nevan, Srebrow, Anabella, Gamarnik, Andrea V
Published in PLoS pathogens (01.08.2016)
Published in PLoS pathogens (01.08.2016)
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Dengue virus targets RBM10 deregulating host cell splicing and innate immune response
Pozzi, Berta, Bragado, Laureano, Mammi, Pablo, Torti, María Florencia, Gaioli, Nicolás, Gebhard, Leopoldo G, García Solá, Martín E, Vaz-Drago, Rita, Iglesias, Néstor G, García, Cybele C, Gamarnik, Andrea V, Srebrow, Anabella
Published in Nucleic acids research (09.07.2020)
Published in Nucleic acids research (09.07.2020)
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Insights into the product release mechanism of dengue virus NS3 helicase
Adler, Natalia S, Cababie, Leila A, Sarto, Carolina, Cavasotto, Claudio N, Gebhard, Leopoldo G, Estrin, Darío A, Gamarnik, Andrea V, Arrar, Mehrnoosh, Kaufman, Sergio B
Published in Nucleic acids research (08.07.2022)
Published in Nucleic acids research (08.07.2022)
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Dengue Virus Genome Uncoating Requires Ubiquitination
Byk, Laura A, Iglesias, Néstor G, De Maio, Federico A, Gebhard, Leopoldo G, Rossi, Mario, Gamarnik, Andrea V
Published in mBio (28.06.2016)
Published in mBio (28.06.2016)
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Overlapping local and long-range RNA-RNA interactions modulate dengue virus genome cyclization and replication
de Borba, Luana, Villordo, Sergio M, Iglesias, Nestor G, Filomatori, Claudia V, Gebhard, Leopoldo G, Gamarnik, Andrea V
Published in Journal of virology (01.03.2015)
Published in Journal of virology (01.03.2015)
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RNA Structure Duplication in the Dengue Virus 3' UTR: Redundancy or Host Specificity?
de Borba, Luana, Villordo, Sergio M, Marsico, Franco L, Carballeda, Juan M, Filomatori, Claudia V, Gebhard, Leopoldo G, Pallarés, Horacio M, Lequime, Sebastian, Lambrechts, Louis, Sánchez Vargas, Irma, Blair, Carol D, Gamarnik, Andrea V
Published in mBio (08.01.2019)
Published in mBio (08.01.2019)
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SARS-CoV-2 surveillance in untreated wastewater: detection of viral RNA in a low-resource community in Buenos Aires, Argentina
Iglesias, Néstor Gabriel, Gebhard, Leopoldo Germán, Carballeda, Juan Manuel, Aiello, Ignacio, Recalde, Emiliano, Terny, Gabriel, Ambrosolio, Silvina, L'Arco, Gabriela, Konfino, Jonatan, Brardinelli, Juan Ignacio
Published in Revista panamericana de salud pública (01.01.2021)
Published in Revista panamericana de salud pública (01.01.2021)
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De novo design approaches targeting an envelope protein pocket to identify small molecules against dengue virus
Leal, Emilse S., Adler, Natalia S., Fernández, Gabriela A., Gebhard, Leopoldo G., Battini, Leandro, Aucar, Maria G., Videla, Mariela, Monge, María Eugenia, Hernández de los Ríos, Alejandro, Acosta Dávila, John Alejandro, Morell, María L., Cordo, Sandra M., García, Cybele C., Gamarnik, Andrea V., Cavasotto, Claudio N., Bollini, Mariela
Published in European journal of medicinal chemistry (15.11.2019)
Published in European journal of medicinal chemistry (15.11.2019)
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Discovery of novel dengue virus entry inhibitors via a structure-based approach
Leal, Emilse S., Aucar, M. Gabriela, Gebhard, Leopoldo G., Iglesias, Nestor G., Pascual, María J., Casal, Juan J., Gamarnik, Andrea V., Cavasotto, Claudio N., Bollini, Mariela
Published in Bioorganic & medicinal chemistry letters (15.08.2017)
Published in Bioorganic & medicinal chemistry letters (15.08.2017)
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Thermodynamic study of the effect of ions on the interaction between dengue virus NS3 helicase and single stranded RNA
Cababie, Leila A, Incicco, J Jeremías, González-Lebrero, Rodolfo M, Roman, Ernesto A, Gebhard, Leopoldo G, Gamarnik, Andrea V, Kaufman, Sergio B
Published in Scientific reports (22.07.2019)
Published in Scientific reports (22.07.2019)
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Monomeric nature of dengue virus NS3 helicase and thermodynamic analysis of the interaction with single-stranded RNA
Gebhard, Leopoldo G, Incicco, J Jeremías, Smal, Clara, Gallo, Mariana, Gamarnik, Andrea V, Kaufman, Sergio B
Published in Nucleic acids research (13.10.2014)
Published in Nucleic acids research (13.10.2014)
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Folding of an Abridged β-Lactamase
Santos, Javier, Gebhard, Leopoldo G, Risso, Valeria A, Ferreyra, Raul G, Rossi, Juan P. F. C, Ermácora, Mario R
Published in Biochemistry (Easton) (17.02.2004)
Published in Biochemistry (Easton) (17.02.2004)
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A Kazal prolyl endopeptidase inhibitor isolated from the skin of Phyllomedusa sauvagii
Gebhard, Leopoldo G., Carrizo, Federico U., Stern, Ana L., Burgardt, Noelia I., Faivovich, Julián, Lavilla, Esteban, Ermácora, Mario R.
Published in European journal of biochemistry (01.06.2004)
Published in European journal of biochemistry (01.06.2004)
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Dengue virus NS5 degrades ERC1 during infection to antagonize NF-kB activation
Gonzalez Lopez Ledesma, María Mora, Costa Navarro, Guadalupe, Pallares, Horacio M, Paletta, Ana, De Maio, Federico, Iglesias, Nestor G, Gebhard, Leopoldo, Oviedo Rouco, Santiago, Ojeda, Diego S, de Borba, Luana, Giraldo, María, Rajsbaum, Ricardo, Ceballos, Ana, Krogan, Nevan J, Shah, Priya S, Gamarnik, Andrea V
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2023)
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Journal Article
Steady-State NTPase Activity of Dengue Virus NS3: Number of Catalytic Sites, Nucleotide Specificity and Activation by ssRNA. e58508
Incicco, J Jeremias, Gebhard, Leopoldo G, Gonzalez-Lebrero, Rodolfo M, Gamarnik, Andrea V, Kaufman, Sergio B
Published in PloS one (01.03.2013)
Published in PloS one (01.03.2013)
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