A new view of transcriptome complexity and regulation through the lens of local splicing variations
Vaquero-Garcia, Jorge, Barrera, Alejandro, Gazzara, Matthew R, González-Vallinas, Juan, Lahens, Nicholas F, Hogenesch, John B, Lynch, Kristen W, Barash, Yoseph
Published in eLife (01.02.2016)
Published in eLife (01.02.2016)
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Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy
Sotillo, Elena, Barrett, David M, Black, Kathryn L, Bagashev, Asen, Oldridge, Derek, Wu, Glendon, Sussman, Robyn, Lanauze, Claudia, Ruella, Marco, Gazzara, Matthew R, Martinez, Nicole M, Harrington, Colleen T, Chung, Elaine Y, Perazzelli, Jessica, Hofmann, Ted J, Maude, Shannon L, Raman, Pichai, Barrera, Alejandro, Gill, Saar, Lacey, Simon F, Melenhorst, Jan J, Allman, David, Jacoby, Elad, Fry, Terry, Mackall, Crystal, Barash, Yoseph, Lynch, Kristen W, Maris, John M, Grupp, Stephan A, Thomas-Tikhonenko, Andrei
Published in Cancer discovery (01.12.2015)
Published in Cancer discovery (01.12.2015)
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RNA splicing analysis using heterogeneous and large RNA-seq datasets
Vaquero-Garcia, Jorge, Aicher, Joseph K, Jewell, San, Gazzara, Matthew R, Radens, Caleb M, Jha, Anupama, Norton, Scott S, Lahens, Nicholas F, Grant, Gregory R, Barash, Yoseph
Published in Nature communications (03.03.2023)
Published in Nature communications (03.03.2023)
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Co-regulatory activity of hnRNP K and NS1-BP in influenza and human mRNA splicing
Thompson, Matthew G, Muñoz-Moreno, Raquel, Bhat, Prasanna, Roytenberg, Renat, Lindberg, John, Gazzara, Matthew R, Mallory, Michael J, Zhang, Ke, García-Sastre, Adolfo, Fontoura, Beatriz M A, Lynch, Kristen W
Published in Nature communications (19.06.2018)
Published in Nature communications (19.06.2018)
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Aberrant splicing in B-cell acute lymphoblastic leukemia
Black, Kathryn L, Naqvi, Ammar S, Asnani, Mukta, Hayer, Katharina E, Yang, Scarlett Y, Gillespie, Elisabeth, Bagashev, Asen, Pillai, Vinodh, Tasian, Sarah K, Gazzara, Matthew R, Carroll, Martin, Taylor, Deanne, Lynch, Kristen W, Barash, Yoseph, Thomas-Tikhonenko, Andrei
Published in Nucleic acids research (30.11.2018)
Published in Nucleic acids research (30.11.2018)
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Journal Article
Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes
Gazzara, Matthew R, Mallory, Michael J, Roytenberg, Renat, Lindberg, John P, Jha, Anupama, Lynch, Kristen W, Barash, Yoseph
Published in Genome research (01.08.2017)
Published in Genome research (01.08.2017)
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Journal Article
RNA Binding Protein CELF2 Regulates Signal-Induced Alternative Polyadenylation by Competing with Enhancers of the Polyadenylation Machinery
Chatrikhi, Rakesh, Mallory, Michael J., Gazzara, Matthew R., Agosto, Laura M., Zhu, Wandi S., Litterman, Adam J., Ansel, K. Mark, Lynch, Kristen W.
Published in Cell reports (Cambridge) (10.09.2019)
Published in Cell reports (Cambridge) (10.09.2019)
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Journal Article
Alternative splicing of HDAC7 regulates its interaction with 14-3-3 proteins to alter histone marks and target gene expression
Agosto, Laura M., Mallory, Michael J., Ferretti, Max B., Blake, Davia, Krick, Keegan S., Gazzara, Matthew R., Garcia, Benjamin A., Lynch, Kristen W.
Published in Cell reports (Cambridge) (28.03.2023)
Published in Cell reports (Cambridge) (28.03.2023)
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Journal Article
Induced transcription and stability of CELF2 mRNA drives widespread alternative splicing during T-cell signaling
Mallory, Michael J., Allon, Samuel J., Qiu, Jinsong, Gazzara, Matthew R., Tapescu, Iulia, Martinez, Nicole M., Fu, Xiang-Dong, Lynch, Kristen W.
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.2015)
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Journal Article
Alternative splicing of apoptosis genes promotes human T cell survival
Blake, Davia, Radens, Caleb M, Ferretti, Max B, Gazzara, Matthew R, Lynch, Kristen W
Published in eLife (20.10.2022)
Published in eLife (20.10.2022)
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Journal Article
Aberrant splicing in B-cell acute lymphoblastic leukemia
Black, Kathryn L, Naqvi, Ammar S, Asnani, Mukta, Hayer, Katharina E, Yang, Scarlett Y, Gillespie, Elisabeth, Bagashev, Asen, Pillai, Vinodh, Tasian, Sarah K, Gazzara, Matthew R, Carroll, Martin, Taylor, Deanne, Lynch, Kristen W, Barash, Yoseph, Thomas-Tikhonenko, Andrei
Published in Nucleic acids research (25.01.2019)
Published in Nucleic acids research (25.01.2019)
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An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning
Ehrmann, Ingrid, Crichton, James H, Gazzara, Matthew R, James, Katherine, Liu, Yilei, Grellscheid, Sushma Nagaraja, Curk, Tomaž, de Rooij, Dirk, Steyn, Jannetta S, Cockell, Simon, Adams, Ian R, Barash, Yoseph, Elliott, David J
Published in eLife (24.01.2019)
Published in eLife (24.01.2019)
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Journal Article
Integrative deep models for alternative splicing
Jha, Anupama, Gazzara, Matthew R, Barash, Yoseph
Published in Bioinformatics (Oxford, England) (15.07.2017)
Published in Bioinformatics (Oxford, England) (15.07.2017)
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Mutator dynamics in sexual and asexual experimental populations of yeast
Raynes, Yevgeniy, Gazzara, Matthew R, Sniegowski, Paul D
Published in BMC evolutionary biology (07.06.2011)
Published in BMC evolutionary biology (07.06.2011)
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Journal Article
A SLM2 Feedback Pathway Controls Cortical Network Activity and Mouse Behavior
Ehrmann, Ingrid, Gazzara, Matthew R., Pagliarini, Vittoria, Dalgliesh, Caroline, Kheirollahi-Chadegani, Mahsa, Xu, Yaobo, Cesari, Eleonora, Danilenko, Marina, Maclennan, Marie, Lowdon, Kate, Vogel, Tanja, Keskivali-Bond, Piia, Wells, Sara, Cater, Heather, Fort, Philippe, Santibanez-Koref, Mauro, Middei, Silvia, Sette, Claudio, Clowry, Gavin J., Barash, Yoseph, Cunningham, Mark O., Elliott, David J.
Published in Cell reports (Cambridge) (20.12.2016)
Published in Cell reports (Cambridge) (20.12.2016)
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Journal Article
CYP11B1 variants influence skeletal maturation via alternative splicing
Grgic, Olja, Gazzara, Matthew R, Chesi, Alessandra, Medina-Gomez, Carolina, Cousminer, Diana L, Mitchell, Jonathan A, Prijatelj, Vid, de Vries, Jard, Shevroja, Enisa, McCormack, Shana E, Kalkwarf, Heidi J, Lappe, Joan M, Gilsanz, Vicente, Oberfield, Sharon E, Shepherd, John A, Kelly, Andrea, Mahboubi, Soroosh, Faucz, Fabio R, Feelders, Richard A, de Jong, Frank H, Uitterlinden, Andre G, Visser, Jenny A, Ghanem, Louis R, Wolvius, Eppo B, Hofland, Leo J, Stratakis, Constantine A, Zemel, Babette S, Barash, Yoseph, Grant, Struan F A, Rivadeneira, Fernando
Published in Communications biology (09.11.2021)
Published in Communications biology (09.11.2021)
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Journal Article
Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19
Asnani, Mukta, Hayer, Katharina E, Naqvi, Ammar S, Zheng, Sisi, Yang, Scarlett Y, Oldridge, Derek, Ibrahim, Fadia, Maragkakis, Manolis, Gazzara, Matthew R, Black, Kathryn L, Bagashev, Asen, Taylor, Deanne, Mourelatos, Zissimos, Grupp, Stephan A, Barrett, David, Maris, John M, Sotillo, Elena, Barash, Yoseph, Thomas-Tikhonenko, Andrei
Published in Leukemia (01.04.2020)
Published in Leukemia (01.04.2020)
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