MEF2 plays a significant role in the tumor inhibitory mechanism of encapsulated RENCA cells via EGF receptor signaling in target tumor cells
Martis, Prithy C, Dudley, Atira T, Bemrose, Melissa A, Gazda, Hunter L, Smith, Barry H, Gazda, Lawrence S
Published in BMC cancer (04.12.2018)
Published in BMC cancer (04.12.2018)
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Yield, cell composition, and function of islets isolated from different ages of neonatal pigs
Arefanian, Hossein, Ramji, Qahir, Gupta, Nancy, Spigelman, Aliya F, Grynoch, Donald, MacDonald, Patrick E, Mueller, Thomas F, Gazda, Lawrence S, Rajotte, Ray V, Rayat, Gina R
Published in Frontiers in endocrinology (Lausanne) (21.12.2022)
Published in Frontiers in endocrinology (Lausanne) (21.12.2022)
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A comprehensive microbiological safety approach for agarose encapsulated porcine islets intended for clinical trials
Gazda, Lawrence S., Collins, James, Lovatt, Archie, Holdcraft, Robert W., Morin, Merribeth J., Galbraith, Daniel, Graham, Melanie, Laramore, Melissa A., Maclean, Christine, Black, John, Milne, Euan W., Marthaler, Douglas G., Vinerean, Horatiu V., Michalak, Michelle M., Hoffer, Deborah, Richter, Steven, Hall, Richard D., Smith, Barry H.
Published in Xenotransplantation (Københaven) (01.11.2016)
Published in Xenotransplantation (Københaven) (01.11.2016)
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Retention of gene expression in porcine islets after agarose encapsulation and long-term culture
Dumpala, Pradeep R., Holdcraft, Robert W., Martis, Prithy C., Laramore, Melissa A., Parker, Thomas S., Levine, Daniel M., Smith, Barry H., Gazda, Lawrence S.
Published in Biochemical and biophysical research communications (05.08.2016)
Published in Biochemical and biophysical research communications (05.08.2016)
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A new model of sciatic inflammatory neuritis (SIN): induction of unilateral and bilateral mechanical allodynia following acute unilateral peri-sciatic immune activation in rats
Chacur, Marucia, Milligan, Erin D, Gazda, Lawrence S, Armstrong, Charles, Wang, Haichao, Tracey, Kevin J, Maier, Steven F, Watkins, Linda R
Published in Pain (Amsterdam) (01.12.2001)
Published in Pain (Amsterdam) (01.12.2001)
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First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 3: Porcine islet product manufacturing and release testing criteria
Rayat, Gina R., Gazda, Lawrence S., Hawthorne, Wayne J., Hering, Bernhard J., Hosking, Peter, Matsumoto, Shinichi, Rajotte, Ray V.
Published in Xenotransplantation (01.01.2016)
Published in Xenotransplantation (01.01.2016)
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Conference Proceeding
Enhancement of in Vitro and in Vivo Function of Agarose-Encapsulated Porcine Islets by Changes in the Islet Microenvironment
Holdcraft, Robert W., Gazda, Lawrence S., Circle, Lisa, Adkins, Hollie, Harbeck, Steven G., Meyer, Eric D., Bautista, Melissa A., Martis, Prithy C., Laramore, Melissa A., Vinerean, Horatiu V., Hall, Richard D., Smith, Barry H.
Published in Cell transplantation (01.01.2014)
Published in Cell transplantation (01.01.2014)
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Clinical laboratory and imaging evidence for effectiveness of agarose-agarose macrobeads containing stem-like cells derived from a mouse renal adenocarcinoma cell population (RMBs) in treatment-resistant, advanced metastatic colorectal cancer: Evaluation of a biological-systems approach to cancer therapy (U.S. FDA IND-BB 10091; NCT 02046174, NCT 01053013)
Smith, Barry H, Gazda, Lawrence S, Fahey, Thomas J, Nazarian, Angelica, Laramore, Melissa A, Martis, Prithy, Andrada, Zoe P, Thomas, Joanne, Parikh, Tapan, Sureshbabu, Sudipta, Berman, Nathaniel, Ocean, Allyson J, Hall, Richard D, Wolf, David J
Published in Chinese journal of cancer research (01.02.2018)
Published in Chinese journal of cancer research (01.02.2018)
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No Evidence of Viral Transmission following Long-Term Implantation of Agarose Encapsulated Porcine Islets in Diabetic Dogs
Carraway, Joseph W., Hall, Richard D., Laramore, Melissa A., Vinerean, Horatiu V., Gazda, Lawrence S., Smith, Barry H.
Published in Journal of Diabetes Research (01.01.2014)
Published in Journal of Diabetes Research (01.01.2014)
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Journal Article
Encapsulation of Porcine Islets Permits Extended Culture Time and Insulin Independence in Spontaneously Diabetic BB Rats
Gazda, Lawrence S., Vinerean, Horatiu V., Laramore, Melissa A., Diehl, Carolyn H., Hall, Richard D., Rubin, Albert L., Smith, Barry H.
Published in Cell transplantation (01.07.2007)
Published in Cell transplantation (01.07.2007)
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Pravastatin Improves Glucose Regulation and Biocompatibility of Agarose Encapsulated Porcine Islets following Transplantation into Pancreatectomized Dogs
Carraway, Joseph W., Hall, Richard D., Laramore, Melissa A., Vinerean, Horatiu V., Gazda, Lawrence S., Smith, Barry H.
Published in Journal of Diabetes Research (01.01.2014)
Published in Journal of Diabetes Research (01.01.2014)
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First-in-Human Phase 1 Trial of Agarose Beads Containing Murine RENCA Cells in Advanced Solid Tumors
Smith, Barry H., Parikh, Tapan, Andrada, Zoe P., Fahey, Thomas J., Berman, Nathaniel, wiles, Madeline, Nazarian, Angelica, Thomas, Joanne, Arreglado, Anna, Akahoho, Eugene, wolf, David J., Levine, Daniel M., Parker, Thomas S., Gazda, Lawrence S., Ocean, Allyson J.
Published in Cancer Growth and Metastasis (01.01.2016)
Published in Cancer Growth and Metastasis (01.01.2016)
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Streptozotocin is responsible for the induction and progression of renal tumorigenesis in diabetic Wistar-Furth rats treated with insulin or transplanted with agarose encapsulated porcine islets
Vinerean, Horatiu V., Gazda, Lawrence S., Hall, Richard D., Smith, Barry H.
Published in Islets (01.07.2011)
Published in Islets (01.07.2011)
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Multiple clinically relevant immunotherapies prolong the function of microencapsulated porcine islet xenografts in diabetic NOD mice without the use of anti‐CD154 mAb
Safley, Susan A., Barber, Graham F., Holdcraft, Robert W., Gazda, Lawrence S., Duncanson, Stephanie, Poznansky, Mark C., Sambanis, Athanassios, Weber, Collin J.
Published in Xenotransplantation (Københaven) (01.07.2020)
Published in Xenotransplantation (Københaven) (01.07.2020)
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Long‐term efficacy and safety of porcine islet macrobeads in nonimmunosuppressed diabetic cynomolgus macaques
Holdcraft, Robert W., Graham, Melanie J., Bemrose, Melissa A., Mutch, Lucas A., Martis, Prithy C., Janecek, Jody L., Hall, Richard D., Smith, Barry H., Gazda, Lawrence S.
Published in Xenotransplantation (Københaven) (01.05.2022)
Published in Xenotransplantation (Københaven) (01.05.2022)
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The Use of Pancreas Biopsy Scoring Provides Reliable Porcine Islet Yields While Encapsulation Permits the Determination of Microbiological Safety
Gazda, Lawrence S., Adkins, Hollie, Bailie, Johannah A., Byrd, Wendy, Circle, Lisa, Conn, Bryan, Diehl, Carolyn H., Hall, Richard D., Rubin, Albert L., Smith, Barry H.
Published in Cell transplantation (01.01.2005)
Published in Cell transplantation (01.01.2005)
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Three-Dimensional Culture of Mouse Renal Carcinoma Cells in Agarose Macrobeads Selects for a Subpopulation of Cells with Cancer Stem Cell or Cancer Progenitor Properties
SMITH, Barry H, GAZDA, Lawrence S, DAVID, Eric M, SUIZHEN QIU, CORDON-CARDO, Carlos, HALL, Richard D, GORDON, Bruce R, DIEHL, Carolyn H, STENZEL, Kurt H, RUBIN, Albert L, CONN, Bryan L, JAIN, Kanti, ASINA, Shirin, LEVINE, Daniel M, PARKER, Thomas S, LARAMORE, Melissa A, MARTIS, Prithy C, VINEREAN, Horatiu V
Published in Cancer research (Chicago, Ill.) (01.02.2011)
Published in Cancer research (Chicago, Ill.) (01.02.2011)
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Journal Article
Treatment of agarose-agarose RENCA macrobeads with docetaxel selects for OCT4+ cells with tumor-initiating capability
Gazda, Lawrence S, Martis, Prithy C, Laramore, Melissa A, Bautista, Melissa A, Dudley, Atira, Vinerean, Horatiu V, Smith, Barry H
Published in Cancer biology & therapy (01.12.2013)
Published in Cancer biology & therapy (01.12.2013)
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