TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia
Zhang, Haojian, Kozono, David E., O’Connor, Kevin W., Vidal-Cardenas, Sofia, Rousseau, Alix, Hamilton, Abigail, Moreau, Lisa, Gaudiano, Emily F., Greenberger, Joel, Bagby, Grover, Soulier, Jean, Grompe, Markus, Parmar, Kalindi, D’Andrea, Alan D.
Published in Cell stem cell (05.05.2016)
Published in Cell stem cell (05.05.2016)
Get full text
Journal Article
USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors
Lim, Kah Suan, Li, Heng, Roberts, Emma A., Gaudiano, Emily F., Clairmont, Connor, Sambel, Larissa Alina, Ponnienselvan, Karthikeyan, Liu, Jessica C., Yang, Chunyu, Kozono, David, Parmar, Kalindi, Yusufzai, Timur, Zheng, Ning, D’Andrea, Alan D.
Published in Molecular cell (20.12.2018)
Published in Molecular cell (20.12.2018)
Get full text
Journal Article
PTPN2 regulates the generation of exhausted CD8 + T cell subpopulations and restrains tumor immunity
LaFleur, Martin W, Nguyen, Thao H, Coxe, Matthew A, Miller, Brian C, Yates, Kathleen B, Gillis, Jacob E, Sen, Debattama R, Gaudiano, Emily F, Al Abosy, Rose, Freeman, Gordon J, Haining, W Nicholas, Sharpe, Arlene H
Published in Nature immunology (01.10.2019)
Published in Nature immunology (01.10.2019)
Get full text
Journal Article
Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models
Davis, Mindy I., Pragani, Rajan, Fox, Jennifer T., Shen, Min, Parmar, Kalindi, Gaudiano, Emily F., Liu, Li, Tanega, Cordelle, McGee, Lauren, Hall, Matthew D., McKnight, Crystal, Shinn, Paul, Nelson, Henrike, Chattopadhyay, Debasish, D'Andrea, Alan D., Auld, Douglas S., DeLucas, Larry J., Li, Zhuyin, Boxer, Matthew B., Simeonov, Anton
Published in The Journal of biological chemistry (18.11.2016)
Published in The Journal of biological chemistry (18.11.2016)
Get full text
Journal Article
Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8 + T Cells
Drijvers, Jefte M, Gillis, Jacob E, Muijlwijk, Tara, Nguyen, Thao H, Gaudiano, Emily F, Harris, Isaac S, LaFleur, Martin W, Ringel, Alison E, Yao, Cong-Hui, Kurmi, Kiran, Juneja, Vikram R, Trombley, Justin D, Haigis, Marcia C, Sharpe, Arlene H
Published in Cancer immunology research (01.02.2021)
Published in Cancer immunology research (01.02.2021)
Get more information
Journal Article
Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade
Rowe, Jared H, Elia, Ilaria, Shahid, Osmaan, Gaudiano, Emily F, Sifnugel, Natalia E, Johnson, Sheila, Reynolds, Amy G, Fung, Megan E, Joshi, Shakchhi, LaFleur, Martin W, Park, Joon Seok, Pauken, Kristen E, Rabinowitz, Joshua D, Freeman, Gordon J, Haigis, Marcia C, Sharpe, Arlene H
Published in Cancer discovery (12.12.2023)
Published in Cancer discovery (12.12.2023)
Get full text
Journal Article
Serum microRNAs are early indicators of survival after radiation-induced hematopoietic injury
Acharya, Sanket S, Fendler, Wojciech, Watson, Jacqueline, Hamilton, Abigail, Pan, Yunfeng, Gaudiano, Emily, Moskwa, Patryk, Bhanja, Payel, Saha, Subhrajit, Guha, Chandan, Parmar, Kalindi, Chowdhury, Dipanjan
Published in Science translational medicine (13.05.2015)
Published in Science translational medicine (13.05.2015)
Get more information
Journal Article
Inactivation of Ebola Virus and SARS-CoV-2 in Cell Culture Supernatants and Cell Pellets by Gamma Irradiation
Boytz, RuthMabel, Seitz, Scott, Gaudiano, Emily, Patten, J J, Keiser, Patrick T, Connor, John H, Sharpe, Arlene H, Davey, Robert A
Published in Viruses (23.12.2022)
Published in Viruses (23.12.2022)
Get full text
Journal Article
Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
Rowe, Jared H., Elia, Ilaria, Shahid, Osmaan, Gaudiano, Emily F., Sifnugel, Natalia E., Johnson, Sheila, Reynolds, Amy G., Fung, Megan E., Joshi, Shakchhi, LaFleur, Martin W., Park, Joon Seok, Pauken, Kristen E., Rabinowitz, Joshua D., Freeman, Gordon J., Haigis, Marcia C., Sharpe, Arlene H.
Published in Cancer discovery (12.12.2023)
Published in Cancer discovery (12.12.2023)
Get full text
Journal Article
Abstract 333: USP1 is required for replication fork stability in BRCA1-deficient tumors
Lim, Kah Suan, Li, Heng, Roberts, Emma A., Gaudiano, Emily F., Clairmont, Connor, Ponnienselvan, Karthikeyan, Liu, Jessica C., Parmar, Kalindi, Zheng, Ning, D'Andrea, Alan
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Get full text
Journal Article
TGF-β Pathway Inhibition Rescues the Function of Hematopoietic Stem and Progenitor Cells Derived from Patients with Fanconi Anemia
Zhang, Haojian, Kozono, David, O'Connor, Kevin, Rousseau, Alix, Moreau, Lisa, Gaudiano, Emily, Greenberger, Joel S, Bagby, Grover C., Soulier, Jean, Grompe, Markus, Parmar, Kalindi, D'Andrea, Alan D
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
Get full text
Journal Article
Bone Marrow Failure in Fanconi Anemia from Hyperactive TGF-β Signaling
Zhang, Haojian, Kozono, David, O’Connor, Kevin, Vidal-Cardenas, Sofia, Hamilton, Abigail, Gaudiano, Emily, Greenberger, Joel S., Grompe, Markus, Parmar, Kalindi, D’Andrea, Alan D.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
Get full text
Journal Article
METHODS AND COMPOSITIONS FOR MODULATION OF PIEZO1 IN THE TREATMENT OF CANCER
SHARPE, Arlene, EISERT, Robyn, KALOCSAY, Marian, GAUDIANO, Emily, BRADSHAW, Gary, LAFLEUR, Martin
Year of Publication 21.03.2024
Get full text
Year of Publication 21.03.2024
Patent