Advances in TRP channel drug discovery: from target validation to clinical studies
Koivisto, Ari-Pekka, Belvisi, Maria G., Gaudet, Rachelle, Szallasi, Arpad
Published in Nature reviews. Drug discovery (01.01.2022)
Published in Nature reviews. Drug discovery (01.01.2022)
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Structural and functional diversity calls for a new classification of ABC transporters
Thomas, Christoph, Aller, Stephen G., Beis, Konstantinos, Carpenter, Elisabeth P., Chang, Geoffrey, Chen, Lei, Dassa, Elie, Dean, Michael, Duong Van Hoa, Franck, Ekiert, Damian, Ford, Robert, Gaudet, Rachelle, Gong, Xin, Holland, I. Barry, Huang, Yihua, Kahne, Daniel K., Kato, Hiroaki, Koronakis, Vassilis, Koth, Christopher M., Lee, Youngsook, Lewinson, Oded, Lill, Roland, Martinoia, Enrico, Murakami, Satoshi, Pinkett, Heather W., Poolman, Bert, Rosenbaum, Daniel, Sarkadi, Balazs, Schmitt, Lutz, Schneider, Erwin, Shi, Yigong, Shyng, Show‐Ling, Slotboom, Dirk J., Tajkhorshid, Emad, Tieleman, D. Peter, Ueda, Kazumitsu, Váradi, András, Wen, Po‐Chao, Yan, Nieng, Zhang, Peng, Zheng, Hongjin, Zimmer, Jochen, Tampé, Robert
Published in FEBS letters (01.12.2020)
Published in FEBS letters (01.12.2020)
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What do we know about the transient receptor potential vanilloid 2 (TRPV2) ion channel?
Perálvarez‐Marín, Alex, Doñate‐Macian, Pau, Gaudet, Rachelle
Published in The FEBS journal (01.11.2013)
Published in The FEBS journal (01.11.2013)
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Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction
Sotomayor, Marcos, Weihofen, Wilhelm A., Gaudet, Rachelle, Corey, David P.
Published in Nature (London) (06.12.2012)
Published in Nature (London) (06.12.2012)
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Sorting out a promiscuous superfamily: towards cadherin connectomics
Sotomayor, Marcos, Gaudet, Rachelle, Corey, David P
Published in Trends in cell biology (01.09.2014)
Published in Trends in cell biology (01.09.2014)
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Distinct properties of Ca2+-calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel
Lau, Sze-Yi, Procko, Erik, Gaudet, Rachelle
Published in The Journal of general physiology (01.11.2012)
Published in The Journal of general physiology (01.11.2012)
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Journal Article
Advances in TRP channel drug discovery: from target validation to clinical studies
Koivisto, Ari-Pekka, Belvisi, Maria G., Gaudet, Rachelle, Szallasi, Arpad
Published in Nature reviews. Drug discovery (01.01.2022)
Published in Nature reviews. Drug discovery (01.01.2022)
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Journal Article
Conserved methionine dictates substrate preference in Nramp-family divalent metal transporters
Bozzi, Aaron T., Bane, Lukas B., Weihofen, Wilhelm A., McCabe, Anne L., Singharoy, Abhishek, Chipot, Christophe J., Schulten, Klaus, Gaudet, Rachelle
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (13.09.2016)
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The Ankyrin Repeats of TRPV1 Bind Multiple Ligands and Modulate Channel Sensitivity
Lishko, Polina V., Procko, Erik, Jin, Xiangshu, Phelps, Christopher B., Gaudet, Rachelle
Published in Neuron (Cambridge, Mass.) (21.06.2007)
Published in Neuron (Cambridge, Mass.) (21.06.2007)
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Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli
Garcia-Elias, Anna, Mrkonjic, Sanela, Pardo-Pastor, Carlos, Inada, Hitoshi, Hellmich, Ute A., Rubio-Moscardó, Fanny, Plata, Cristina, Gaudet, Rachelle, Vicente, Rubén, Valverde, Miguel A.
Published in Proceedings of the National Academy of Sciences - PNAS (04.06.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (04.06.2013)
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Journal Article
Structural Determinants of Cadherin-23 Function in Hearing and Deafness
Sotomayor, Marcos, Weihofen, Wilhelm A., Gaudet, Rachelle, Corey, David P.
Published in Neuron (Cambridge, Mass.) (15.04.2010)
Published in Neuron (Cambridge, Mass.) (15.04.2010)
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