LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes
SHIH, C, CHEN, V. J, ANDIS, S. L, BEWLEY, J. R, RAYL, E. A, MOROSON, B. A, BEARDSLEY, G. P, KOHLER, W, RATNAM, M, SCHULTZ, R. M, GOSSETT, L. S, GATES, S. B, MACKELLAR, W. C, HABECK, L. L, SHACKELFORD, K. A, MENDELSOHN, L. G, SOOSE, D. J, PATEL, V. F
Published in Cancer research (Chicago, Ill.) (15.03.1997)
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Published in Cancer research (Chicago, Ill.) (15.03.1997)
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Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis
Mendelsohn, L G, Shih, C, Chen, V J, Habeck, L L, Gates, S B, Shackelford, K A
Published in Seminars in oncology (01.04.1999)
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Published in Seminars in oncology (01.04.1999)
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Sulfonimidamide analogs of oncolytic sulfonylureas
Toth, JE, Grindey, GB, Ehlhardt, WJ, Ray, JE, Boder, GB, Bewley, Klingerman, KK, Gates, SB, Rinzel, SM, Schultz, RM, Weir, LC, Worzalla, JF
Published in Journal of medicinal chemistry (14.03.1997)
Published in Journal of medicinal chemistry (14.03.1997)
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Characterization of folate receptor from normal and neoplastic murine tissue: influence of dietary folate on folate receptor expression
GATES, S. B, MENDELSOHN, L. G, SHACKELFORD, K. A, HABECK, L. L, KURSAR, J. D, GOSSETT, L. S, WORZALLA, J. F, SHIH, C, GRINDEY, G. B
Published in Clinical cancer research (01.07.1996)
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Published in Clinical cancer research (01.07.1996)
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The synthesis and biological activity of a series of 2,4-diaminopyrido[2,3- D]pyrimidine based antifolates as antineoplastic and antiarthritic agents
Gossett, Lynn S., Habeck, Lillian L., Shackelford, Katherine A., Mendelsohn, Laurane G., Gates, Susan B., Worzalla, John F., Self, Tracy D., Theobald, Karla S., Andis, Sherri L., Schultz, Richard M., Shih, Chuan
Published in Bioorganic & medicinal chemistry letters (04.01.1999)
Published in Bioorganic & medicinal chemistry letters (04.01.1999)
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Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases
Sayre, Peter H, Finer-Moore, Janet S, Fritz, Timothy A, Biermann, Donna, Gates, Susan B, MacKellar, Warren C, Patel, Vinod F, Stroud, Robert M
Published in Journal of molecular biology (02.11.2001)
Published in Journal of molecular biology (02.11.2001)
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The role of dietary folate in modulation of folate receptor expression, folylpolyglutamate synthetase activity and the efficacy and toxicity of lometrexol
Mendelsohn, Laurane G., Gates, Susan B., Habeck, Lillian L., Shackelford, Katherine A., Worzalla, John, Shih, Chuan, Grindey, Gerald B.
Published in Advances in enzyme regulation (1996)
Published in Advances in enzyme regulation (1996)
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The Antiproliferative and Cell Cycle Effects of 5,6,7,8-Tetrahydro-N5,N10-Carbonylfolic Acid, an Inhibitor of Methylenetetrahydrofolate Dehydrogenase, Are Potentiated by Hypoxanthine
Tonkinson, J L, Habeck, L L, Toth, J E, Mendelsohn, L G, Bewley, J, Shackelford, K A, Gates, S B, Ray, J, Chen, V J
Published in The Journal of pharmacology and experimental therapeutics (01.10.1998)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1998)
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Herbert Brian Squire. 1909-1961
Gates, S. B., Young, A. D.
Published in Biographical memoirs of fellows of the Royal Society (01.11.1962)
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Published in Biographical memoirs of fellows of the Royal Society (01.11.1962)
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Herbert Brian Squire
Gates, S B, Young, A D
Published in Biographical memoirs of fellows of the Royal Society (01.01.1962)
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Published in Biographical memoirs of fellows of the Royal Society (01.01.1962)
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Synthesis and biological evaluation of a new series of dihydrofolate reductase inhibitors based on the 4-(2,6-diamino-5-pyrimidinyl)alkyl-L-glutamic acid structure
Gossett, Lynn S., Habeck, Lillian L., Gates, Susan B., Andis, Sherri L., Worzalla, John F., Schultz, Richard M., Mendelsonn, Laurane G., Kohler, William, Ratnam, Manohar, Grindey, Gerald B., Shih, Chuan
Published in Bioorganic & medicinal chemistry letters (20.02.1996)
Published in Bioorganic & medicinal chemistry letters (20.02.1996)
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