Local unfolding of the HSP27 monomer regulates chaperone activity
Alderson, T. Reid, Roche, Julien, Gastall, Heidi Y., Dias, David M., Pritišanac, Iva, Ying, Jinfa, Bax, Ad, Benesch, Justin L. P., Baldwin, Andrew J.
Published in Nature communications (06.03.2019)
Published in Nature communications (06.03.2019)
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Journal Article
A weakened interface in the P182L variant of HSP27 associated with severe Charcot‐Marie‐Tooth neuropathy causes aberrant binding to interacting proteins
Reid Alderson, T, Adriaenssens, Elias, Asselbergh, Bob, Pritišanac, Iva, Van Lent, Jonas, Gastall, Heidi Y, Wälti, Marielle A, Louis, John M, Timmerman, Vincent, Baldwin, Andrew J, LP Benesch, Justin
Published in The EMBO journal (15.04.2021)
Published in The EMBO journal (15.04.2021)
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Journal Article
Phosphomimics Destabilize Hsp27 Oligomeric Assemblies and Enhance Chaperone Activity
Jovcevski, Blagojce, Kelly, Megan A., Rote, Anthea P., Berg, Tracey, Gastall, Heidi Y., Benesch, Justin L.P., Aquilina, J. Andrew, Ecroyd, Heath
Published in Chemistry & biology (19.02.2015)
Published in Chemistry & biology (19.02.2015)
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Journal Article
HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C
Collier, Miranda P, Alderson, T Reid, de Villiers, Carin P, Nicholls, Daisy, Gastall, Heidi Y, Allison, Timothy M, Degiacomi, Matteo T, Jiang, He, Mlynek, Georg, Fürst, Dieter O, van der Ven, Peter F M, Djinovic-Carugo, Kristina, Baldwin, Andrew J, Watkins, Hugh, Gehmlich, Katja, Benesch, Justin L P
Published in Science advances (01.05.2019)
Published in Science advances (01.05.2019)
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Journal Article
Dysregulated interactions triggered by a neuropathy-causing mutation in the IPV motif of HSP27
T Reid Alderson, Adriaenssens, Elias, Asselbergh, Bob, Pritisanac, Iva, Gastall, Heidi Y, Walti, Marielle A, Louis, John M, Timmerman, Vincent, Baldwin, Andrew, Benesch, Justin L P
Published in bioRxiv (10.09.2019)
Published in bioRxiv (10.09.2019)
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