Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells
GALLEGOS, A, GASDASKA, J. R, TAYLOR, C. W, PAINE-MURRIETA, G. D, GOODMAN, D, GASDASKA, P. Y, BERGGREN, M, BRIEHL, M. M, POWIS, G
Published in Cancer research (Chicago, Ill.) (15.12.1996)
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Published in Cancer research (Chicago, Ill.) (15.12.1996)
Journal Article
Site-directed mutagenesis of active site cysteines in human thioredoxin produces competitive inhibitors of human thioredoxin reductase and elimination of mitogenic properties of thioredoxin
OBLONG, J. E, BERGGREN, M, GASDAKSA, P. Y, POWIS, G
Published in The Journal of biological chemistry (22.04.1994)
Published in The Journal of biological chemistry (22.04.1994)
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Journal Article
Over-expression of DT-diaphorase in transfected NIH 3T3 cells does not lead to increased anticancer quinone drug sensitivity: a questionable role for the enzyme as a target for bioreductively activated anticancer drugs
Powis, G, Gasdaska, P Y, Gallegos, A, Sherrill, K, Goodman, D
Published in Anticancer research (01.07.1995)
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Published in Anticancer research (01.07.1995)
Journal Article
The thioredoxin/thioredoxin reductase redox system and control of cell growth
Powis, G, Oblong, J E, Gasdaska, P Y, Berggren, M, Hill, S R, Kirkpatrick, D L
Published in Oncology research (1994)
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Published in Oncology research (1994)
Journal Article
Cloning and sequencing of a human thioredoxin reductase
Gasdaska, Pamela Y., Gasdaska, John R., Cochran, Shawn, Powis, Garth
Published in FEBS letters (02.10.1995)
Published in FEBS letters (02.10.1995)
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Journal Article
Regulation of Human Thioredoxin Reductase Expression and Activity by 3′-Untranslated Region Selenocysteine Insertion Sequence and mRNA Instability Elements
Gasdaska, John R., Harney, John W., Gasdaska, Pamela Y., Powis, Garth, Berry, Marla J.
Published in The Journal of biological chemistry (03.09.1999)
Published in The Journal of biological chemistry (03.09.1999)
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Journal Article
Cloning, sequencing and functional expression of a novel human thioredoxin reductase
Gasdaska, Pamela Y., Berggren, Margareta M., Berry, Marla J., Powis, Garth
Published in FEBS letters (08.01.1999)
Published in FEBS letters (08.01.1999)
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Journal Article
Selenium and the thioredoxin redox system: effects on cell growth and death
Powis, G, Gasdaska, J R, Gasdaska, P Y, Berggren, M, Kirkpatrick, D L, Engman, L, Cotgreave, I A, Angulo, M, Baker, A
Published in Oncology research (1997)
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Published in Oncology research (1997)
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Cigarette smoking is a determinant of DT-diaphorase gene expression in human non-small cell lung carcinoma
GASDASKA, P. Y, POWIS, G, HYMAN, P, FISHER, H
Published in Cancer research (Chicago, Ill.) (15.11.1993)
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Published in Cancer research (Chicago, Ill.) (15.11.1993)
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Site-directed mutagenesis of Lys super(36) in human thioredoxin: The highly conserved residue affects reduction rates and growth stimulation but is not essential for the redox protein's biochemical or biological properties
Oblong, JE, Berggren, M, Gasdaska, P Y, Hill, SR, Powis, G
Published in Biochemistry (Easton) (01.01.1995)
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Published in Biochemistry (Easton) (01.01.1995)
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Site-Directed Mutagenesis of Lys36 in Human Thioredoxin: The Highly Conserved Residue Affects Reduction Rates and Growth Stimulation but Is Not Essential for the Redox Protein's Biochemical or Biological Properties
Oblong, John E, Berggren, Margareta, Gasdaska, Pamela Y, Hill, Simon R, Powis, Garth
Published in Biochemistry (Easton) (01.03.1995)
Published in Biochemistry (Easton) (01.03.1995)
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The predicted amino acid sequence of human thioredoxin is identical to that of the autocrine growth factor human adult T-cell derived factor (ADF): thioredoxin mRNA is elevated in some human tumors
Gasdaska, P Y, Oblong, J E, Cotgreave, I A, Powis, G
Published in Biochimica et biophysica acta (02.08.1994)
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Published in Biochimica et biophysica acta (02.08.1994)
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