A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
He, Shaoqing, McPhaul, Christopher, Li, John Zhong, Garuti, Rita, Kinch, Lisa, Grishin, Nick V., Cohen, Jonathan C., Hobbs, Helen H.
Published in The Journal of biological chemistry (26.02.2010)
Published in The Journal of biological chemistry (26.02.2010)
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Binding of Proprotein Convertase Subtilisin/Kexin Type 9 to Epidermal Growth Factor-like Repeat A of Low Density Lipoprotein Receptor Decreases Receptor Recycling and Increases Degradation
Zhang, Da-Wei, Lagace, Thomas A., Garuti, Rita, Zhao, Zhenze, McDonald, Meghan, Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.
Published in The Journal of biological chemistry (22.06.2007)
Published in The Journal of biological chemistry (22.06.2007)
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Journal Article
Decreased Plasma Cholesterol and Hypersensitivity to Statins in Mice Lacking Pcsk9
Rashid, Shirya, Curtis, David E., Garuti, Rita, Anderson, Norma N., Bashmakov, Yuriy, Ho, Y. K., Hammer, Robert E., Moon, Young-Ah, Horton, Jay D., Goldstein, Joseph L.
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (12.04.2005)
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Journal Article
S-nitrosylation of ARH is required for LDL uptake by the LDL receptor
Zhao, Zhenze, Pompey, Shanica, Dong, Hongyun, Weng, Jian, Garuti, Rita, Michaely, Peter
Published in Journal of lipid research (01.06.2013)
Published in Journal of lipid research (01.06.2013)
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Journal Article
The Modular Adaptor Protein Autosomal Recessive Hypercholesterolemia (ARH) Promotes Low Density Lipoprotein Receptor Clustering into Clathrin-coated Pits
Garuti, Rita, Jones, Christopher, Li, Wei-Ping, Michaely, Peter, Herz, Joachim, Gerard, Robert D., Cohen, Jonathan C., Hobbs, Helen H.
Published in The Journal of biological chemistry (09.12.2005)
Published in The Journal of biological chemistry (09.12.2005)
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Journal Article
Transcriptional Regulation of Human CYP27 Integrates Retinoid, Peroxisome Proliferator-Activated Receptor, and Liver X Receptor Signaling in Macrophages
Szanto, Attila, Benko, Szilvia, Szatmari, Istvan, Balint, Balint L., Furtos, Ibolya, Rühl, Ralph, Molnar, Sandor, Csiba, Laszlo, Garuti, Rita, Calandra, Sebastiano, Larsson, Hanna, Diczfalusy, Ulf, Nagy, Laszlo
Published in Molecular and Cellular Biology (01.09.2004)
Published in Molecular and Cellular Biology (01.09.2004)
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Journal Article
A novel mutation in the sterol 27-hydroxylase gene of a woman with autosomal recessive cerebrotendinous xanthomatosis
Schneider, Hauke, Lingesleben, Alexandra, Vogel, Hans-Peter, Garuti, Rita, Calandra, Sebastiano
Published in Orphanet journal of rare diseases (06.10.2010)
Published in Orphanet journal of rare diseases (06.10.2010)
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Journal Article
Identification of a VLDL-induced, FDNPVY-independent internalization mechanism for the LDLR
Michaely, Peter, Zhao, Zhenze, Li, Wei-Ping, Garuti, Rita, Huang, Lily J, Hobbs, Helen H, Cohen, Jonathan C
Published in The EMBO journal (25.07.2007)
Published in The EMBO journal (25.07.2007)
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Journal Article
Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and inlivers of parabiotic mice
Lagace, Thomas A., Curtis, David E., Garuti, Rita, McNutt, Markey C., Park, Sahng Wook, Prather, Heidi B., Anderson, Norma N., Ho, Y.K., Hammer, Robert E., Horton, Jay D.
Published in The Journal of clinical investigation (01.11.2006)
Published in The Journal of clinical investigation (01.11.2006)
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Journal Article
Abnormal splicing of ABCA1 pre-mRNA in Tangier disease due to a IVS2 +5G>C mutation in ABCA1 gene
Altilia, Serena, Pisciotta, Livia, Garuti, Rita, Tarugi, Patrizia, Cantafora, Alfredo, Calabresi, Laura, Tagliabue, Jacopo, Maccari, Sergio, Bernini, Franco, Zanotti, Ilaria, Vergani, Carlo, Bertolini, Stefano, Calandra, Sebastiano
Published in Journal of lipid research (01.02.2003)
Published in Journal of lipid research (01.02.2003)
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Journal Article
Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy
Pattingre, Sophie, Tassa, Amina, Qu, Xueping, Garuti, Rita, Liang, Xiao Huan, Mizushima, Noboru, Packer, Milton, Schneider, Michael D., Levine, Beth
Published in Cell (23.09.2005)
Published in Cell (23.09.2005)
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Journal Article
Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice
Lagace, Thomas A, Curtis, David E, Garuti, Rita, McNutt, Markey C, Park, Sahng Wook, Prather, Heidi B, Anderson, Norma N, Ho, Y K, Hammer, Robert E, Horton, Jay D
Published in The Journal of clinical investigation (01.11.2006)
Published in The Journal of clinical investigation (01.11.2006)
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Journal Article
Analysis of two duplications of the LDL receptor gene affectingintracellular transport, catabolism, and surface binding of the LDLreceptor
Patel, Dilip.D., Lelli, Nicoletta, Garuti, Rita, Li Volti, Salvatore, Bertolini, Stefano, Knight, Brian L., Calandra, Sebastiano
Published in Journal of lipid research (01.07.1998)
Published in Journal of lipid research (01.07.1998)
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Journal Article
Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia
Jones, Christopher, Garuti, Rita, Michaely, Peter, Li, Wei-Ping, Maeda, Nobuyo, Cohen, Jonathan C, Herz, Joachim, Hobbs, Helen H
Published in The Journal of clinical investigation (01.01.2007)
Published in The Journal of clinical investigation (01.01.2007)
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Journal Article
Functional analysis of the promoter of human sterol 27-hydroxylase gene in HepG2 cells
Garuti, Rita, Croce, Maria Antonietta, Piccinini, Luana, Tiozzo, Roberta, Bertolini, Stefano, Calandra, Sebastiano
Published in Gene (23.01.2002)
Published in Gene (23.01.2002)
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Journal Article
Influence of beta(0)-thalassemia on the phenotypic expression of heterozygous familial hypercholesterolemia : a study of patients with familial hypercholesterolemia from Sardinia
Deiana, L, Garuti, R, Pes, G M, Carru, C, Errigo, A, Rolleri, M, Pisciotta, L, Masturzo, P, Cantafora, A, Calandra, S, Bertolini, S
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2000)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.01.2000)
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