Protein Tyrosine Phosphatases in Hypothalamic Insulin and Leptin Signaling
Zhang, Zhong-Yin, Dodd, Garron T, Tiganis, Tony
Published in Trends in pharmacological sciences (Regular ed.) (01.10.2015)
Published in Trends in pharmacological sciences (Regular ed.) (01.10.2015)
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Journal Article
The Thermogenic Effect of Leptin Is Dependent on a Distinct Population of Prolactin-Releasing Peptide Neurons in the Dorsomedial Hypothalamus
Dodd, Garron T., Worth, Amy A., Nunn, Nicolas, Korpal, Aaron K., Bechtold, David A., Allison, Margaret B., Myers, Martin G., Statnick, Michael A., Luckman, Simon M.
Published in Cell metabolism (07.10.2014)
Published in Cell metabolism (07.10.2014)
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Journal Article
Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat
Dodd, Garron T., Decherf, Stephanie, Loh, Kim, Simonds, Stephanie E., Wiede, Florian, Balland, Eglantine, Merry, Troy L., Münzberg, Heike, Zhang, Zhong-Yin, Kahn, Barbara B., Neel, Benjamin G., Bence, Kendra K., Andrews, Zane B., Cowley, Michael A., Tiganis, Tony
Published in Cell (15.01.2015)
Published in Cell (15.01.2015)
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Journal Article
Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity
Dodd, Garron T., Xirouchaki, Chrysovalantou E., Eramo, Matthew, Mitchell, Christina A., Andrews, Zane B., Henry, Belinda A., Cowley, Michael A., Tiganis, Tony
Published in Cell reports (Cambridge) (10.09.2019)
Published in Cell reports (Cambridge) (10.09.2019)
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Journal Article
Insulin regulates POMC neuronal plasticity to control glucose metabolism
Dodd, Garron T, Michael, Natalie J, Lee-Young, Robert S, Mangiafico, Salvatore P, Pryor, Jack T, Munder, Astrid C, Simonds, Stephanie E, Brüning, Jens Claus, Zhang, Zhong-Yin, Cowley, Michael A, Andrikopoulos, Sofianos, Horvath, Tamas L, Spanswick, David, Tiganis, Tony
Published in eLife (19.09.2018)
Published in eLife (19.09.2018)
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Journal Article
Leptin Signaling in the Arcuate Nucleus Reduces Insulin’s Capacity to Suppress Hepatic Glucose Production in Obese Mice
Balland, Eglantine, Chen, Weiyi, Dodd, Garron T., Conductier, Gregory, Coppari, Roberto, Tiganis, Tony, Cowley, Michael A.
Published in Cell reports (Cambridge) (08.01.2019)
Published in Cell reports (Cambridge) (08.01.2019)
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Journal Article
PTPN2 phosphatase deletion in T cells promotes anti‐tumour immunity and CAR T‐cell efficacy in solid tumours
Wiede, Florian, Lu, Kun‐Hui, Du, Xin, Liang, Shuwei, Hochheiser, Katharina, Dodd, Garron T, Goh, Pei K, Kearney, Conor, Meyran, Deborah, Beavis, Paul A, Henderson, Melissa A, Park, Simone L, Waithman, Jason, Zhang, Sheng, Zhang, Zhong‐Yin, Oliaro, Jane, Gebhardt, Thomas, Darcy, Phillip K, Tiganis, Tony
Published in The EMBO journal (15.01.2020)
Published in The EMBO journal (15.01.2020)
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Journal Article
The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling
Worth, Amy A, Shoop, Rosemary, Tye, Katie, Feetham, Claire H, D'Agostino, Giuseppe, Dodd, Garron T, Reimann, Frank, Gribble, Fiona M, Beebe, Emily C, Dunbar, James D, Alexander-Chacko, Jesline T, Sindelar, Dana K, Coskun, Tamer, Emmerson, Paul J, Luckman, Simon M
Published in eLife (29.07.2020)
Published in eLife (29.07.2020)
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Journal Article
TCPTP Regulates Insulin Signalling in AgRP Neurons to Coordinate Glucose Metabolism with Feeding
Dodd, Garron T, Lee-Young, Robert S, Brüning, Jens C, Tiganis, Tony
Published in Diabetes (New York, N.Y.) (01.07.2018)
Published in Diabetes (New York, N.Y.) (01.07.2018)
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Journal Article
Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice
Merry, Troy L., Tran, Melanie, Dodd, Garron T., Mangiafico, Salvatore P., Wiede, Florian, Kaur, Supreet, McLean, Catriona L., Andrikopoulos, Sofianos, Tiganis, Tony
Published in Diabetologia (01.12.2016)
Published in Diabetologia (01.12.2016)
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Journal Article
The peptide hemopressin acts through CB1 cannabinoid receptors to reduce food intake in rats and mice
Dodd, Garron T, Mancini, Giacomo, Lutz, Beat, Luckman, Simon M
Published in The Journal of neuroscience (26.05.2010)
Published in The Journal of neuroscience (26.05.2010)
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Journal Article
Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus
Kyriakou, Eleni, Schmidt, Stefanie, Dodd, Garron T, Pfuhlmann, Katrin, Simonds, Stephanie E, Lenhart, Dominik, Geerlof, Arie, Schriever, Sonja C, De Angelis, Meri, Schramm, Karl-Werner, Plettenburg, Oliver, Cowley, Michael A, Tiganis, Tony, Tschöp, Matthias H, Pfluger, Paul T, Sattler, Michael, Messias, Ana C
Published in Journal of medicinal chemistry (27.12.2018)
Published in Journal of medicinal chemistry (27.12.2018)
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Journal Article
High-fat-fed obese glutathione peroxidase 1-deficient mice exhibit defective insulin secretion but protection from hepatic steatosis and liver damage
Merry, Troy L, Tran, Melanie, Stathopoulos, Maria, Wiede, Florian, Fam, Barbara Christianne, Dodd, Garron T, Clarke, Iain, Watt, Matthew J, Andrikopoulos, Sofianos, Tiganis, Tony
Published in Antioxidants & redox signaling (10.05.2014)
Published in Antioxidants & redox signaling (10.05.2014)
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Journal Article
Engineering of a Biologically Active Glycosylated Glucagon-Like Peptide‑1 Analogue
Chandrashekar, Chaitra, Lin, Feng, Nishiuchi, Yuji, Mohammed, Sam F., White, Barbara F., Arsenakis, Yanni, Yuliantie, Elita, Zhao, Peishen, van Dun, Sam, Koijen, Anna, Kajihara, Yasuhiro, Wootten, Denise, Dodd, Garron T., van den Bos, Leendert J., Wade, John D., Hossain, Mohammed Akhter
Published in Journal of medicinal chemistry (09.05.2024)
Published in Journal of medicinal chemistry (09.05.2024)
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Journal Article
Pathogenic hypothalamic extracellular matrix promotes metabolic disease
Beddows, Cait A., Shi, Feiyue, Horton, Anna L., Dalal, Sagar, Zhang, Ping, Ling, Chang-Chun, Yong, V. Wee, Loh, Kim, Cho, Ellie, Karagiannis, Chris, Rose, Adam J., Montgomery, Magdalene K., Gregorevic, Paul, Watt, Matthew J., Packer, Nicolle H., Parker, Benjamin L., Brown, Robyn M., Moh, Edward S. X., Dodd, Garron T.
Published in Nature (London) (26.09.2024)
Published in Nature (London) (26.09.2024)
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Journal Article
Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function
Blazev, Ronnie, Carl, Christian S, Ng, Yaan-Kit, Molendijk, Jeffrey, Voldstedlund, Christian T, Zhao, Yuanyuan, Xiao, Di, Kueh, Andrew J, Miotto, Paula M, Haynes, Vanessa R, Hardee, Justin P, Chung, Jin D, McNamara, James W, Qian, Hongwei, Gregorevic, Paul, Oakhill, Jonathan S, Herold, Marco J, Jensen, Thomas E, Lisowski, Leszek, Lynch, Gordon S, Dodd, Garron T, Watt, Matthew J, Yang, Pengyi, Kiens, Bente, Richter, Erik A, Parker, Benjamin L
Published in Cell metabolism (04.10.2022)
Published in Cell metabolism (04.10.2022)
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Journal Article
A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding
Dodd, Garron T., Andrews, Zane B., Simonds, Stephanie E., Michael, Natalie J., DeVeer, Michael, Brüning, Jens C., Spanswick, David, Cowley, Michael A., Tiganis, Tony
Published in Cell metabolism (01.08.2017)
Published in Cell metabolism (01.08.2017)
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