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Chung, Stephen S, Eng, William S, Hu, Wenhuo, Khalaj, Mona, Garrett-Bakelman, Francine E, Tavakkoli, Montreh, Levine, Ross L, Carroll, Martin, Klimek, Virginia M, Melnick, Ari M, Park, Christopher Y
Published in Science translational medicine (25.01.2017)
Published in Science translational medicine (25.01.2017)
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DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
Batra, Rajbir Nath, Lifshitz, Aviezer, Vidakovic, Ana Tufegdzic, Chin, Suet-Feung, Sati-Batra, Ankita, Sammut, Stephen-John, Provenzano, Elena, Ali, H. Raza, Dariush, Ali, Bruna, Alejandra, Murphy, Leigh, Purushotham, Arnie, Ellis, Ian, Green, Andrew, Garrett-Bakelman, Francine E., Mason, Chris, Melnick, Ari, Aparicio, Samuel A. J. R., Rueda, Oscar M., Tanay, Amos, Caldas, Carlos
Published in Nature communications (13.09.2021)
Published in Nature communications (13.09.2021)
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Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers
Glass, Jacob L, Hassane, Duane, Wouters, Bas J, Kunimoto, Hiroyoshi, Avellino, Roberto, Garrett-Bakelman, Francine E, Guryanova, Olga A, Bowman, Robert, Redlich, Shira, Intlekofer, Andrew M, Meydan, Cem, Qin, Tingting, Fall, Mame, Alonso, Alicia, Guzman, Monica L, Valk, Peter J M, Thompson, Craig B, Levine, Ross, Elemento, Olivier, Delwel, Ruud, Melnick, Ari, Figueroa, Maria E
Published in Cancer discovery (01.08.2017)
Published in Cancer discovery (01.08.2017)
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Temporal Telomere and DNA Damage Responses in the Space Radiation Environment
Luxton, Jared J., McKenna, Miles J., Taylor, Lynn E., George, Kerry A., Zwart, Sara R., Crucian, Brian E., Drel, Viktor R., Garrett-Bakelman, Francine E., Mackay, Matthew J., Butler, Daniel, Foox, Jonathan, Grigorev, Kirill, Bezdan, Daniela, Meydan, Cem, Smith, Scott M., Sharma, Kumar, Mason, Christopher E., Bailey, Susan M.
Published in Cell reports (Cambridge) (08.12.2020)
Published in Cell reports (Cambridge) (08.12.2020)
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Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia
Akalin, Altuna, Garrett-Bakelman, Francine E, Kormaksson, Matthias, Busuttil, Jennifer, Zhang, Lu, Khrebtukova, Irina, Milne, Thomas A, Huang, Yongsheng, Biswas, Debabrata, Hess, Jay L, Allis, C David, Roeder, Robert G, Valk, Peter J M, Löwenberg, Bob, Delwel, Ruud, Fernandez, Hugo F, Paietta, Elisabeth, Tallman, Martin S, Schroth, Gary P, Mason, Christopher E, Melnick, Ari, Figueroa, Maria E
Published in PLoS genetics (01.06.2012)
Published in PLoS genetics (01.06.2012)
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COCOA: coordinate covariation analysis of epigenetic heterogeneity
Lawson, John T., Smith, Jason P., Bekiranov, Stefan, Garrett-Bakelman, Francine E., Sheffield, Nathan C.
Published in Genome Biology (07.09.2020)
Published in Genome Biology (07.09.2020)
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An optimized algorithm for detecting and annotating regional differential methylation
Li, Sheng, Garrett-Bakelman, Francine E, Akalin, Altuna, Zumbo, Paul, Levine, Ross, To, Bik L, Lewis, Ian D, Brown, Anna L, D'Andrea, Richard J, Melnick, Ari, Mason, Christopher E
Published in BMC bioinformatics (10.04.2013)
Published in BMC bioinformatics (10.04.2013)
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Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML
Duy, Cihangir, Teater, Matt, Garrett-Bakelman, Francine E, Lee, Tak C, Meydan, Cem, Glass, Jacob L, Li, Meng, Hellmuth, Johannes C, Mohammad, Helai P, Smitheman, Kimberly N, Shih, Alan H, Abdel-Wahab, Omar, Tallman, Martin S, Guzman, Monica L, Muench, David, Grimes, H Leighton, Roboz, Gail J, Kruger, Ryan G, Creasy, Caretha L, Paietta, Elisabeth M, Levine, Ross L, Carroll, Martin, Melnick, Ari M
Published in Cancer discovery (01.07.2019)
Published in Cancer discovery (01.07.2019)
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Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA
Hu, Xiaowei, Logan, Jeongok G., Kwon, Younghoon, Lima, Joao A. C., Jacobs, David R., Duprez, Daniel, Brumback, Lyndia, Taylor, Kent D., Durda, Peter, Johnson, W. Craig, Cornell, Elaine, Guo, Xiuqing, Liu, Yongmei, Tracy, Russell P., Blackwell, Thomas W., Papanicolaou, George, Mitchell, Gary F., Rich, Stephen S., Rotter, Jerome I., Van Den Berg, David J., Chirinos, Julio A., Hughes, Timothy M., Garrett-Bakelman, Francine E., Manichaikul, Ani
Published in Scientific reports (17.10.2023)
Published in Scientific reports (17.10.2023)
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Aid is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells
Kunimoto, Hiroyoshi, McKenney, Anna Sophia, Meydan, Cem, Shank, Kaitlyn, Nazir, Abbas, Rapaport, Franck, Durham, Benjamin, Garrett-Bakelman, Francine E., Pronier, Elodie, Shih, Alan H., Melnick, Ari, Chaudhuri, Jayanta, Levine, Ross L.
Published in Blood (30.03.2017)
Published in Blood (30.03.2017)
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Targeted detection and quantitation of histone modifications from 1,000 cells
Abshiru, Nebiyu A, Sikora, Jacek W, Camarillo, Jeannie M, Morris, Juliette A, Compton, Philip D, Lee, Tak, Neelamraju, Yaseswini, Haddox, Samuel, Sheridan, Caroline, Carroll, Martin, Cripe, Larry D, Tallman, Martin S, Paietta, Elisabeth M, Melnick, Ari M, Thomas, Paul M, Garrett-Bakelman, Francine E, Kelleher, Neil L
Published in PloS one (26.10.2020)
Published in PloS one (26.10.2020)
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Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers
Bezdan, Daniela, Grigorev, Kirill, Meydan, Cem, Pelissier Vatter, Fanny A., Cioffi, Michele, Rao, Varsha, MacKay, Matthew, Nakahira, Kiichi, Burnham, Philip, Afshinnekoo, Ebrahim, Westover, Craig, Butler, Daniel, Mozsary, Chris, Donahoe, Timothy, Foox, Jonathan, Mishra, Tejaswini, Lucotti, Serena, Rana, Brinda K., Melnick, Ari M., Zhang, Haiying, Matei, Irina, Kelsen, David, Yu, Kenneth, Lyden, David C., Taylor, Lynn, Bailey, Susan M., Snyder, Michael P., Garrett-Bakelman, Francine E., Ossowski, Stephan, De Vlaminck, Iwijn, Mason, Christopher E.
Published in iScience (18.12.2020)
Published in iScience (18.12.2020)
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Correction: Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group’s clinical trial E3999
Rapaport, Franck, Seier, Kenneth, Neelamraju, Yaseswini, Hassane, Duane, Baslan, Timour, Gildea, Daniel T., Haddox, Samuel, Lee, Tak, Murdock, H. Moses, Sheridan, Caroline, Thurmond, Alexis, Wang, Ling, Carroll, Martin, Cripe, Larry D., Fernandez, Hugo, Mason, Christopher E., Paietta, Elisabeth, Roboz, Gail J., Sun, Zhuoxin, Tallman, Martin S., Zhang, Yanming, Gönen, Mithat, Levine, Ross, Melnick, Ari M., Kleppe, Maria, Garrett-Bakelman, Francine E.
Published in Blood cancer journal (New York) (06.07.2023)
Published in Blood cancer journal (New York) (06.07.2023)
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Journal Article
Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group’s clinical trial E3999
Rapaport, Franck, Seier, Kenneth, Neelamraju, Yaseswini, Hassane, Duane, Baslan, Timour, Gildea, Daniel T., Haddox, Samuel, Lee, Tak, Murdock, H. Moses, Sheridan, Caroline, Thurmond, Alexis, Wang, Ling, Carroll, Martin, Cripe, Larry D., Fernandez, Hugo, Mason, Christopher E., Paietta, Elisabeth, Roboz, Gail J., Sun, Zhuoxin, Tallman, Martin S., Zhang, Yanming, Gönen, Mithat, Levine, Ross, Melnick, Ari M., Kleppe, Maria, Garrett-Bakelman, Francine E.
Published in Blood cancer journal (New York) (23.09.2022)
Published in Blood cancer journal (New York) (23.09.2022)
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The N 6 -methyladenosine (m 6 A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
Vu, Ly P, Pickering, Brian F, Cheng, Yuanming, Zaccara, Sara, Nguyen, Diu, Minuesa, Gerard, Chou, Timothy, Chow, Arthur, Saletore, Yogesh, MacKay, Matthew, Schulman, Jessica, Famulare, Christopher, Patel, Minal, Klimek, Virginia M, Garrett-Bakelman, Francine E, Melnick, Ari, Carroll, Martin, Mason, Christopher E, Jaffrey, Samie R, Kharas, Michael G
Published in Nature medicine (01.11.2017)
Published in Nature medicine (01.11.2017)
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An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions
Sevilla, Ana, Papatsenko, Dimitri, Mazloom, Amin R, Xu, Huilei, Vasileva, Ana, Unwin, Richard D, LeRoy, Gary, Chen, Edward Y, Garrett-Bakelman, Francine E, Lee, Dung-Fang, Trinite, Benjamin, Webb, Ryan L, Wang, Zichen, Su, Jie, Gingold, Julian, Melnick, Ari, Garcia, Benjamin A, Whetton, Anthony D, MacArthur, Ben D, Ma'ayan, Avi, Lemischka, Ihor R
Published in Frontiers in cell and developmental biology (19.03.2021)
Published in Frontiers in cell and developmental biology (19.03.2021)
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Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence
Duy, Cihangir, Li, Meng, Teater, Matt, Meydan, Cem, Garrett-Bakelman, Francine E, Lee, Tak C, Chin, Christopher R, Durmaz, Ceyda, Kawabata, Kimihito C, Dhimolea, Eugen, Mitsiades, Constantine S, Doehner, Hartmut, D'Andrea, Richard J, Becker, Michael W, Paietta, Elisabeth M, Mason, Christopher E, Carroll, Martin, Melnick, Ari M
Published in Cancer discovery (01.06.2021)
Published in Cancer discovery (01.06.2021)
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DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling
Guryanova, Olga A, Shank, Kaitlyn, Spitzer, Barbara, Luciani, Luisa, Koche, Richard P, Garrett-Bakelman, Francine E, Ganzel, Chezi, Durham, Benjamin H, Mohanty, Abhinita, Hoermann, Gregor, Rivera, Sharon A, Chramiec, Alan G, Pronier, Elodie, Bastian, Lennart, Keller, Matthew D, Tovbin, Daniel, Loizou, Evangelia, Weinstein, Abby R, Gonzalez, Adriana Rodriguez, Lieu, Yen K, Rowe, Jacob M, Pastore, Friederike, McKenney, Anna Sophia, Krivtsov, Andrei V, Sperr, Wolfgang R, Cross, Justin R, Mason, Christopher E, Tallman, Martin S, Arcila, Maria E, Abdel-Wahab, Omar, Armstrong, Scott A, Kubicek, Stefan, Staber, Philipp B, Gönen, Mithat, Paietta, Elisabeth M, Melnick, Ari M, Nimer, Stephen D, Mukherjee, Siddhartha, Levine, Ross L
Published in Nature medicine (01.12.2016)
Published in Nature medicine (01.12.2016)
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