Ex Vivo Interleukin-12-Priming During CD8+ T Cell Activation Dramatically Improves Adoptive T Cell Transfer Antitumor Efficacy in a Lymphodepleted Host
Rubinstein, Mark P., PhD, Cloud, Colleen A., BS, Garrett, Tracy E., BS, Moore, Caitlin J., BS, Schwartz, Kristina M, Johnson, C. Bryce, BS, Craig, David H., PhD, Salem, Mohamed L., PhD, Paulos, Chrystal M., PhD, Cole, David J., MD, FACS
Published in Journal of the American College of Surgeons (01.04.2012)
Published in Journal of the American College of Surgeons (01.04.2012)
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Conference Proceeding
Effective Targeting of Multiple B-Cell Maturation Antigen-Expressing Hematological Malignances by Anti-B-Cell Maturation Antigen Chimeric Antigen Receptor T Cells
Friedman, Kevin M, Garrett, Tracy E, Evans, John W, Horton, Holly M, Latimer, Howard J, Seidel, Stacie L, Horvath, Christopher J, Morgan, Richard A
Published in Human gene therapy (01.05.2018)
Published in Human gene therapy (01.05.2018)
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Rational design of a SOCS1-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens
Schlabach, Michael R, Lin, Sharon, Collester, Zachary R, Wrocklage, Christopher, Shenker, Sol, Calnan, Conor, Xu, Tianlei, Gannon, Hugh S, Williams, Leila J, Thompson, Frank, Dunbar, Paul R, LaMothe, Robert A, Garrett, Tracy E, Colletti, Nicholas, Hohmann, Anja F, Tubo, Noah J, Bullock, Caroline P, Le Mercier, Isabelle, Sofjan, Katri, Merkin, Jason J, Keegan, Sean, Kryukov, Gregory V, Dugopolski, Caroline, Stegmeier, Frank, Wong, Karrie, Sharp, Fiona A, Cadzow, Louise, Benson, Micah J
Published in The Journal of clinical investigation (15.12.2023)
Published in The Journal of clinical investigation (15.12.2023)
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Sensitive and adaptable pharmacological control of CAR T cells through extracellular receptor dimerization
Leung, Wai-Hang, Gay, Joel, Martin, Unja, Garrett, Tracy E, Horton, Holly M, Certo, Michael T, Blazar, Bruce R, Morgan, Richard A, Gregory, Philip D, Jarjour, Jordan, Astrakhan, Alexander
Published in JCI insight (06.06.2019)
Published in JCI insight (06.06.2019)
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Journal Article
Rational design of a SOCSI-edited tumor-infiltrating lymphocyte therapy using CRISPR/Cas9 screens
Schlabach, Michael R, Lin, Sharon, Collester, Zachary R, Wrocklage, Christopher, Shenker, Sol, Calnan, Conor, Xu, Tianlei, Gannon, Hugh S, Williams, Leila J, Thompson, Frank, Dunbar, Paul R, LaMothe, Robert A, Garrett, Tracy E, Colletti, Nicholas, Hohmann, Anja F, Tubo, Noah J, Bullock, Caroline P, Mercier, Isabelle Le, Sofjan, Katri, Merkin, Jason J, Keegan, Sean, Kryukov, Gregory V, Dugopolski, Caroline, Stegmeier, Frank, Wong, Karrie, Sharp, Fiona A, Cadzow, Louise, Benson, Micah J
Published in The Journal of clinical investigation (15.12.2023)
Published in The Journal of clinical investigation (15.12.2023)
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Abstract 2175: KSQ-001: A CRISPR/Cas9-engineered tumor infiltrating lymphocyte (eTILTM) therapy for solid tumors
Schlabach, Mike, Colletti, Nick, Hohmann, Anja, Wrocklage, Christopher, Gannon, Hugh, Falla, Alejandra, Tubo, Noah, LaMothe, Robert A., Bullock, Caroline, Mitchell, Pete T., Hafeez, Nafeeza, Sathithloetsakun, Suphinya, Grasberger, Paula E., Le Mercier, Isabelle, Garrett, Tracy E., Keegan, Sean, Shenker, Sol, Franco, Charlotte, Stegmeier, Frank, Kryukov, Gregory V., Cadzow, Louise, Benson, Micah
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Abstract 2296: Inhibition of the PI3K/Akt pathway during CAR T cell production results in enhanced efficacy across multiple in vivo tumor models
Grande, Shannon, Perkins, Molly R., Hamel, Amanda, Horton, Holly M., Eng, Fay, Rhodes, Claire J., Garrett, Tracy E., Miller, Sara M., Evans, John W., Latimer, Howard J., Horvath, Christopher, Kuczewski, Michael, Friedman, Kevin, Morgan, Richard A.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 2296: Inhibition of the PI3KAkt pathway during CAR T cell production results in enhanced efficacy across multiple in vivo tumor models
Grande, Shannon, Perkins, Molly R, Hamel, Amanda, Horton, Holly M, Eng, Fay, Rhodes, Claire J, Garrett, Tracy E, Miller, Sara M, Evans, John W, Latimer, Howard J, Horvath, Christopher, Kuczewski, Michael, Friedman, Kevin, Morgan, Richard A
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Manufacturing an Enhanced CAR T Cell Product By Inhibition of the PI3K/Akt Pathway During T Cell Expansion Results in Improved In Vivo Efficacy of Anti-BCMA CAR T Cells
Perkins, Molly R., Grande, Shannon, Hamel, Amanda, Horton, Holly M., Garrett, Tracy E., Miller, Sara M., Latimer, Howard J., Horvath, Christopher J., Kuczewski, Michael, Friedman, Kevin M., Morgan, Richard A.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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A Novel and Highly Potent CAR T Cell Drug Product for Treatment of BCMA-Expressing Hematological Malignances
Chekmasova, Alena A., Horton, Holly M., Garrett, Tracy E., Evans, John W., Griecci, Johanna, Hamel, Amanda, Latimer, Howard J., Seidel, Stacie L., Ryu, Byoung Y., Kuczewski, Michael, Horvath, Christopher J., Friedman, Kevin M., Morgan, Richard A.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Ex vivo IL-12-Priming during CD8+ T Cell Activation Dramatically Improves Adoptive T Cell Transfer Anti-Tumor Efficacy in a Lymphodepleted Host
Rubinstein, Mark P, Cloud, Colleen A, Garrett, Tracy E, Moore, Caitlin J, Schwartz, Kristina M, Johnson, C Bryce, Craig, David H, Salem, Mohamed L, Paulos, Chrystal M, Cole, David J
Published in Journal of the American College of Surgeons (22.02.2012)
Published in Journal of the American College of Surgeons (22.02.2012)
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A BCMA-specific CAR T cell produced with clinically scalable lentiviral and T cell manufacturing processes has potent anti-multiple myeloma activity
Garrett, Tracy E, Chekmasova, Alena A, Evans, John W, Seidel, Stacie L, Horton, Holly M, Latimer, Howard J, Griecci, Johanna A, Horvath, Christopher J, Ryu, Byoung Y, Friedman, Kevin M, Morgan, Richard A
Published in Journal for immunotherapy of cancer (04.11.2015)
Published in Journal for immunotherapy of cancer (04.11.2015)
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