SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus
Branche, Emilie, Wang, Ying-Ting, Viramontes, Karla M., Valls Cuevas, Joan M., Xie, Jialei, Ana-Sosa-Batiz, Fernanda, Shafee, Norazizah, Duttke, Sascha H., McMillan, Rachel E., Clark, Alex E., Nguyen, Michael N., Garretson, Aaron F., Crames, Jan J., Spann, Nathan J., Zhu, Zhe, Rich, Jeremy N., Spector, Deborah H., Benner, Christopher, Shresta, Sujan, Carlin, Aaron F.
Published in Nature communications (12.09.2022)
Published in Nature communications (12.09.2022)
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Identification of global inhibitors of cellular glycosylation
Sørensen, Daniel Madriz, Büll, Christian, Madsen, Thomas D., Lira-Navarrete, Erandi, Clausen, Thomas Mandel, Clark, Alex E., Garretson, Aaron F., Karlsson, Richard, Pijnenborg, Johan F. A., Yin, Xin, Miller, Rebecca L., Chanda, Sumit K., Boltje, Thomas J., Schjoldager, Katrine T., Vakhrushev, Sergey Y., Halim, Adnan, Esko, Jeffrey D., Carlin, Aaron F., Hurtado-Guerrero, Ramon, Weigert, Roberto, Clausen, Henrik, Narimatsu, Yoshiki
Published in Nature communications (20.02.2023)
Published in Nature communications (20.02.2023)
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SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
Clausen, Thomas Mandel, Sandoval, Daniel R., Spliid, Charlotte B., Pihl, Jessica, Perrett, Hailee R., Painter, Chelsea D., Narayanan, Anoop, Majowicz, Sydney A., Kwong, Elizabeth M., McVicar, Rachael N., Thacker, Bryan E., Glass, Charles A., Yang, Zhang, Torres, Jonathan L., Golden, Gregory J., Bartels, Phillip L., Porell, Ryan N., Garretson, Aaron F., Laubach, Logan, Feldman, Jared, Yin, Xin, Pu, Yuan, Hauser, Blake M., Caradonna, Timothy M., Kellman, Benjamin P., Martino, Cameron, Gordts, Philip L.S.M., Chanda, Sumit K., Schmidt, Aaron G., Godula, Kamil, Leibel, Sandra L., Jose, Joyce, Corbett, Kevin D., Ward, Andrew B., Carlin, Aaron F., Esko, Jeffrey D.
Published in Cell (12.11.2020)
Published in Cell (12.11.2020)
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Virologic and Immunologic Characterization of Coronavirus Disease 2019 Recrudescence After Nirmatrelvir/Ritonavir Treatment
Carlin, Aaron F, Clark, Alex E, Chaillon, Antoine, Garretson, Aaron F, Bray, William, Porrachia, Magali, Santos, AsherLev T, Rana, Tariq M, Smith, Davey M
Published in Clinical infectious diseases (08.02.2023)
Published in Clinical infectious diseases (08.02.2023)
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Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs
Schooley, Robert T, Carlin, Aaron F, Beadle, James R, Valiaeva, Nadejda, Zhang, Xing-Quan, Clark, Alex E, McMillan, Rachel E, Leibel, Sandra L, McVicar, Rachael N, Xie, Jialei, Garretson, Aaron F, Smith, Victoria I, Murphy, Joyce, Hostetler, Karl Y
Published in Antimicrobial agents and chemotherapy (17.09.2021)
Published in Antimicrobial agents and chemotherapy (17.09.2021)
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Oral pharmacokinetics and efficacy of oral phospholipid remdesivir nucleoside prodrugs against SARS-CoV-2 in mice
Carlin, Aaron F, Beadle, James R, Ardanuy, Jeremy, Clark, Alex E, Rhodes, Victoria, Garretson, Aaron F, Murphy, Joyce A, Valiaeva, Nadejda, Schooley, Robert T, Frieman, Matthew B, Hostetler, Karl Y
Published in Antimicrobial agents and chemotherapy (08.10.2024)
Published in Antimicrobial agents and chemotherapy (08.10.2024)
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1‑O‑Octadecyl-2‑O‑benzyl-sn-glyceryl-3-phospho-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV‑2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV‑2 Activity
Carlin, Aaron F., Beadle, James R., Clark, Alex E., Gully, Kendra L., Moreira, Fernando R., Baric, Ralph S., Graham, Rachel L., Valiaeva, Nadejda, Leibel, Sandra L., Bray, William, McMillan, Rachel E., Freshman, Jonathan E., Garretson, Aaron F., McVicar, Rachael N., Rana, Tariq, Zhang, Xing-Quan, Murphy, Joyce A., Schooley, Robert T., Hostetler, Karl Y.
Published in Journal of medicinal chemistry (27.04.2023)
Published in Journal of medicinal chemistry (27.04.2023)
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Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs
McMillan, Rachel E., Lo, Michael K., Zhang, Xing-Quan, Beadle, James R., Valiaeva, Nadejda, Garretson, Aaron F., Clark, Alex E., Freshman, Jon E., Murphy, Joyce, Montgomery, Joel M., Spiropoulou, Christina F., Schooley, Robert T., Hostetler, Karl Y., Carlin, Aaron F.
Published in Antiviral research (01.11.2023)
Published in Antiviral research (01.11.2023)
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Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity
Inde, Zintis, Croker, Ben A, Yapp, Clarence, Joshi, Gaurav N, Spetz, Johan, Fraser, Cameron, Qin, Xingping, Xu, Le, Deskin, Brian, Ghelfi, Elisa, Webb, Gabrielle, Carlin, Aaron F, Zhu, Yanfang Peipei, Leibel, Sandra L, Garretson, Aaron F, Clark, Alex E, Duran, Jason M, Pretorius, Victor, Crotty-Alexander, Laura E, Li, Chendi, Lee, Jamie Casey, Sodhi, Chhinder, Hackam, David J, Sun, Xin, Hata, Aaron N, Kobzik, Lester, Miller, Jeffrey, Park, Jin-Ah, Brownfield, Douglas, Jia, Hongpeng, Sarosiek, Kristopher A
Published in Science advances (01.08.2021)
Published in Science advances (01.08.2021)
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MoSAIC: Mobile Surveillance for Acute Respiratory Infections and Influenza-Like Illness in the Community
STOCKWELL, Melissa S, REED, Carrie, VARGAS, Celibell Y, CAMARGO, Stewin, GARRETSON, Aaron F, ALBA, Luis R, LARUSSA, Philip, FINELLI, Lyn, LARSON, Elaine L, SAIMAN, Lisa
Published in American Journal of Epidemiology (15.12.2014)
Published in American Journal of Epidemiology (15.12.2014)
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Neutralizing Antibody Responses After Severe Acute Respiratory Syndrome Coronavirus 2 BA.2 and BA.2.12.1 Infection Do Not Neutralize BA.4 and BA.5 and Can Be Blunted by Nirmatrelvir/Ritonavir Treatment
Carlin, Aaron F, Clark, Alex E, Garretson, Aaron F, Bray, William, Porrachia, Magali, Santos, AsherLev T, Rana, Tariq M, Chaillon, Antoine, Smith, Davey M
Published in Open forum infectious diseases (01.04.2023)
Published in Open forum infectious diseases (01.04.2023)
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Virologic and Immunologic Characterization of COVID-19 Recrudescence after Nirmatrelvir/Ritonavir Treatment
Carlin, Aaron F, Clark, Alex E, Chaillon, Antoine, Garretson, Aaron F, Bray, William, Porrachi, Magali, Santos, AsherLev T, Smith, Davey M
Published in Research square (18.05.2022)
Published in Research square (18.05.2022)
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Rethinking Remdesivir: Synthesis, Antiviral Activity and Pharmacokinetics of Oral Lipid Prodrugs
Schooley, Robert T, Carlin, Aaron F, Beadle, James R, Valiaeva, Nadejda, Zhang, Xing-Quan, Clark, Alex E, McMillan, Rachel E, Leibel, Sandra L, McVicar, Rachael N, Xie, Jialei, Garretson, Aaron F, Smith, Victoria I, Murphy, Joyce, Hostetler, Karl Y
Published in bioRxiv (07.06.2021)
Published in bioRxiv (07.06.2021)
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The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection
Sandoval, Daniel R, Clausen, Thomas Mandel, Nora, Chelsea, Cribbs, Adam P, Denardo, Andrea, Clark, Alex E, Garretson, Aaron F, Coker, Joanna K C, Narayanan, Anoop, Majowicz, Sydney A, Philpott, Martin, Johansson, Catrine, Dunford, James E, Spliid, Charlotte B, Golden, Gregory J, Payne, N Connor, Tye, Mark A, Nowell, Cameron J, Griffis, Eric R, Piermatteo, Ann, Grunddal, Kaare V, Alle, Thibault, Magida, Jason A, Hauser, Blake M, Feldman, Jared, Caradonna, Timothy M, Pu, Yuan, Yin, Xin, McVicar, Rachael N, Kwong, Elizabeth M, Weiss, Ryan J, Downes, Michael, Tsimikas, Sotirios, Smidt, Aaron G, Ballatore, Carlo, Zengler, Karsten, Evans, Ron M, Chanda, Sumit K, Croker, Ben A, Leibel, Sandra L, Jose, Joyce, Mazitschek, Ralph, Oppermann, Udo, Esko, Jeffrey D, Carlin, Aaron F, Gordts, Philip L S M
Published in bioRxiv (26.03.2021)
Published in bioRxiv (26.03.2021)
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SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
Clausen, Thomas Mandel, Sandoval, Daniel R, Spliid, Charlotte B, Pihl, Jessica, Painter, Chelsea D, Thacker, Bryan E, Glass, Charles A, Narayanan, Anoop, Majowicz, Sydney A, Zhang, Yang, Torres, Jonathan L, Golden, Gregory J, Porell, Ryan, Garretson, Aaron F, Laubach, Logan, Feldman, Jared, Yin, Xin, Pu, Yuan, Hauser, Blake, Caradonna, Timothy M, Kellman, Benjamin P, Martino, Cameron, Gordts, Philip L S M, Leibel, Sandra L, Chanda, Summit K, Schmidt, Aaron G, Godula, Kamil, Jose, Joyce, Corbett, Kevin D, Ward, Andrew B, Carlin, Aaron F, Esko, Jeffrey D
Published in bioRxiv : the preprint server for biology (14.07.2020)
Published in bioRxiv : the preprint server for biology (14.07.2020)
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Silver Nanoparticle Sensor Array for the Detection of SARS-CoV‑2
Lam, Benjamin, Retout, Maurice, Clark, Alex E., Garretson, Aaron F., Carlin, Aaron F., Jokerst, Jesse V.
Published in ACS applied nano materials (26.04.2024)
Published in ACS applied nano materials (26.04.2024)
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