Pemetrexed plus platinum with or without pembrolizumab in patients with previously untreated metastatic nonsquamous NSCLC: protocol-specified final analysis from KEYNOTE-189
Rodríguez-Abreu, D., Powell, S.F., Hochmair, M.J., Gadgeel, S., Esteban, E., Felip, E., Speranza, G., De Angelis, F., Dómine, M., Cheng, S.Y., Bischoff, H.G., Peled, N., Reck, M., Hui, R., Garon, E.B., Boyer, M., Kurata, T., Yang, J., Pietanza, M.C., Souza, F., Garassino, M.C.
Published in Annals of oncology (01.07.2021)
Published in Annals of oncology (01.07.2021)
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EGFR mutation subtypes and response to immune checkpoint blockade treatment in non-small-cell lung cancer
Hastings, K., Yu, H.A., Wei, W., Sanchez-Vega, F., DeVeaux, M., Choi, J., Rizvi, H., Lisberg, A., Truini, A., Lydon, C.A., Liu, Z., Henick, B.S., Wurtz, A., Cai, G., Plodkowski, A.J., Long, N.M., Halpenny, D.F., Killam, J., Oliva, I., Schultz, N., Riely, G.J., Arcila, M.E., Ladanyi, M., Zelterman, D., Herbst, R.S., Goldberg, S.B., Awad, M.M., Garon, E.B., Gettinger, S., Hellmann, M.D., Politi, K.
Published in Annals of oncology (01.08.2019)
Published in Annals of oncology (01.08.2019)
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Pembrolizumab as first-line therapy for patients with PD-L1-positive advanced non-small cell lung cancer: a phase 1 trial
Hui, R., Garon, E.B., Goldman, J.W., Leighl, N.B., Hellmann, M.D., Patnaik, A., Gandhi, L., Eder, J.P., Ahn, M.-J., Horn, L., Felip, E., Carcereny, E., Rangwala, R., Lubiniecki, G.M., Zhang, J., Emancipator, K., Roach, C., Rizvi, N.A.
Published in Annals of oncology (01.04.2017)
Published in Annals of oncology (01.04.2017)
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A randomized, placebo-controlled phase 2 study of ganitumab (AMG 479) or conatumumab (AMG 655) in combination with gemcitabine in patients with metastatic pancreatic cancer
Kindler, H.L., Richards, D.A., Garbo, L.E., Garon, E.B., Stephenson, J.J., Rocha-Lima, C.M., Safran, H., Chan, D., Kocs, D.M., Galimi, F., McGreivy, J., Bray, S.L., Hei, Y., Feigal, E.G., Loh, E., Fuchs, C.S.
Published in Annals of oncology (01.11.2012)
Published in Annals of oncology (01.11.2012)
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A phase III study of belagenpumatucel-L, an allogeneic tumour cell vaccine, as maintenance therapy for non-small cell lung cancer
Giaccone, G, Bazhenova, L.A, Nemunaitis, J, Tan, M, Juhász, E, Ramlau, R, van den Heuvel, M.M, Lal, R, Kloecker, G.H, Eaton, K.D, Chu, Q, Dunlop, D.J, Jain, M, Garon, E.B, Davis, C.S, Carrier, E, Moses, S.C, Shawler, D.L, Fakhrai, H
Published in European journal of cancer (1990) (01.11.2015)
Published in European journal of cancer (1990) (01.11.2015)
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Meta-analysis of individual patient safety data from six randomized, placebo-controlled trials with the antiangiogenic VEGFR2-binding monoclonal antibody ramucirumab
Arnold, D., Fuchs, C.S., Tabernero, J., Ohtsu, A., Zhu, A.X., Garon, E.B., Mackey, J.R., Paz-Ares, L., Baron, A.D., Okusaka, T., Yoshino, T., Yoon, H.H., Das, M., Ferry, D., Zhang, Y., Lin, Y., Binder, P., Sashegyi, A., Chau, I.
Published in Annals of oncology (01.12.2017)
Published in Annals of oncology (01.12.2017)
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Systematic evaluation of pembrolizumab dosing in patients with advanced non-small-cell lung cancer
Chatterjee, M., Turner, D.C., Felip, E., Lena, H., Cappuzzo, F., Horn, L., Garon, E.B., Hui, R., Arkenau, H.-T., Gubens, M.A., Hellmann, M.D., Dong, D., Li, C., Mayawala, K., Freshwater, T., Ahamadi, M., Stone, J., Lubiniecki, G.M., Zhang, J., Im, E., De Alwis, D.P., Kondic, A.G., Fløtten, Ø.
Published in Annals of oncology (01.07.2016)
Published in Annals of oncology (01.07.2016)
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Use of archival versus newly collected tumor samples for assessing PD-L1 expression and overall survival: an updated analysis of KEYNOTE-010 trial
Herbst, R.S., Baas, P., Perez-Gracia, J.L., Felip, E., Kim, D.-W., Han, J.-Y., Molina, J.R., Kim, J.-H., Dubos Arvis, C., Ahn, M.-J., Majem, M., Fidler, M.J., Surmont, V., de Castro, G., Garrido, M., Shentu, Y., Emancipator, K., Samkari, A., Jensen, E.H., Lubiniecki, G.M., Garon, E.B.
Published in Annals of oncology (01.02.2019)
Published in Annals of oncology (01.02.2019)
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A phase II study (ARCHER 1042) to evaluate prophylactic treatment of dacomitinib-induced dermatologic and gastrointestinal adverse events in advanced non-small-cell lung cancer
Lacouture, M.E., Keefe, D.M., Sonis, S., Jatoi, A., Gernhardt, D., Wang, T., Doherty, J.P., Giri, N., Nadanaciva, S., O'Connell, J., Sbar, E., Piperdi, B., Garon, E.B.
Published in Annals of oncology (01.09.2016)
Published in Annals of oncology (01.09.2016)
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RELAY, ramucirumab plus erlotinib versus placebo plus erlotinib in patients with untreated, EGFR-mutated, metastatic non-small cell lung cancer: Europe/United States subset analysis
Ponce Aix, S, Novello, S, Garon, EB, Nakagawa, K, Nadal, E, Moro-Sibilot, D, Alonso Garcia, M, Fabre, E, Frimodt-Moller, B, Zimmermann, AH, Visseren-Grul, CM, Reck, M
Published in Cancer treatment and research communications (2021)
Published in Cancer treatment and research communications (2021)
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Results of the GEOMETRY mono-1 phase II study for evaluation of the MET inhibitor capmatinib (INC280) in patients (pts) with METΔex14 mutated advanced non-small cell lung cancer (NSCLC)
Wolf, J., Seto, T., Han, J.-Y., Reguart, N., Garon, E.B., Groen, H.J.M., Tan, D.S., Hida, T., de Jonge, M.J.A., Orlov, S.V., Smit, E.F., Souquet, P.-J., Vansteenkiste, J.F., Giovannini, M., Le Mouhaer, S., Robeva, A., Waldron-Lynch, M., Heist, R.S.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Efficacy and safety of first-line durvalumab (D) ± tremelimumab (T) vs platinum-based chemotherapy (CT) based on clinical characteristics in patients with metastatic (m) NSCLC: Results from MYSTIC
Cho, B.C., Reinmuth, N., Lee, K.H., Ahn, M.-J., Luft, A., Van den Heuvel, M., Dols, M. Cobo, Smolin, A., Vicente, D., Moiseyenko, V., Antonia, S.J., Moulec, S. Le, Robinet, G., Natale, R., Garon, E.B., Nakagawa, K., Liu, F., Thiyagarajah, P., Peters, S., Rizvi, N.A.
Published in Annals of oncology (01.04.2019)
Published in Annals of oncology (01.04.2019)
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Ramucirumab plus erlotinib versus placebo plus erlotinib in previously untreated EGFR-mutated metastatic non-small-cell lung cancer (RELAY): exploratory analysis of next-generation sequencing results
Garon, E.B., Reck, M., Nishio, K., Heymach, J.V., Nishio, M., Novello, S., Paz-Ares, L., Popat, S., Aix, S. Ponce, Graham, H., Butts, B.D., Visseren-Grul, C., Nakagawa, K.
Published in ESMO open (01.08.2023)
Published in ESMO open (01.08.2023)
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Long-term survival in patients (pts) with advanced NSCLC in the KEYNOTE-010 study overall and in pts who completed two years of pembrolizumab (pembro)
Herbst, R.S., Garon, E.B., Kim, D.-W., Chul Cho, B., Pérez Gracia, J.L., Han, J.-Y., Dubos Arvis, C., Majem, M., Forster, M., Monnet, I., Novello, S., Szalai, Z., Gubens, M.A., Su, W.-C., Ceresoli, G.L., Samkari, A., Jensen, E., Lubiniecki, G.M., Baas, P.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Journal Article
KEYNOTE-189 study of pembrolizumab (pembro) plus pemetrexed (pem) and platinum vs placebo plus pem and platinum for untreated, metastatic, nonsquamous NSCLC: Does choice of platinum affect outcomes?
Rodriguez Abreu, D., Garassino, M.C., Esteban, E., Speranza, G., Felip, E., Domine, M., Hochmair, M.J., Powell, S.F., Cheng, S.Y.-S., Bischoff, H., Peled, N., Hui, R., Reck, M., Garon, E.B., Boyer, M., Grossi, F., Jennens, R., Yang, J., Pietanza, M.C., Gadgeel, S.M.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Randomized phase 1b/3 study of erlotinib plus ramucirumab in first-line EGFR mut + stage IV NSCLC: phase 1b safety results
Nakagawa, K., Garon, E.B., Paz-Ares, L., Ponce, S., Corral Jaime, J., Juan Vidal, O., Nadal, E., Kiura, K., He, S., Treat, J., Dalal, R., Lee, P., Reck, M., Novello, S.
Published in Annals of oncology (01.10.2017)
Published in Annals of oncology (01.10.2017)
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Journal Article
KEYNOTE-189 study of pembrolizumab (pembro) plus pemetrexed (pem) and platinum vs placebo plus pem and platinum for untreated, metastatic, nonsquamous NSCLC: Does choice of platinum affect outcomes?
Rodriguez Abreu, D., Garassino, M.C., Esteban, E., Speranza, G., Felip, E., Domine, M., Hochmair, M.J., Powell, S., Cheng, S.Y.-S., Bischoff, H.G., Peled, N., Hui, R., Reck, M., Garon, E.B., Boyer, M., Grossi, F., Jennens, R., Yang, J., Pietanza, M.C., Gadgeel, S.
Published in Annals of oncology (01.11.2018)
Published in Annals of oncology (01.11.2018)
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Responses and durability of clinical benefit in non-small cell lung cancer treated with pegilodecakin in combination with anti-PD-1 inhibitors
Garon, E.B., Wong, D.J., Schneider, J.G., Aljumaily, R., Korn, W.M., Patel, M.R., Autio, K.A., Papadopoulos, K.P., Naing, A., Gabrail, N., Munster, P.N., Goldman, J., Hung, A., Oft, M., Leveque, J., Spigel, D.R.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Journal Article
OA04.06 Evaluation of TMB in KEYNOTE-189: Pembrolizumab Plus Chemotherapy vs Placebo Plus Chemotherapy for Nonsquamous NSCLC
Garassino, M., Rodriguez-Abreu, D., Gadgeel, S., Esteban, E., Felip, E., Speranza, G., Reck, M., Hui, R., Boyer, M., Cristescu, R., Aurora-Garg, D., Albright, A., Loboda, A., Kobie, J., Lunceford, J., Ayers, M., Lubiniecki, G., Piperdi, B., Pietanza, M.C., Garon, E.
Published in Journal of thoracic oncology (01.10.2019)
Published in Journal of thoracic oncology (01.10.2019)
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