The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity
Seillet, Cyril, Luong, Kylie, Tellier, Julie, Jacquelot, Nicolas, Shen, Rui Dong, Hickey, Peter, Wimmer, Verena C., Whitehead, Lachlan, Rogers, Kelly, Smyth, Gordon K., Garnham, Alexandra L., Ritchie, Matthew E., Belz, Gabrielle T.
Published in Nature immunology (01.02.2020)
Published in Nature immunology (01.02.2020)
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Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection
Doerflinger, Marcel, Deng, Yexuan, Whitney, Paul, Salvamoser, Ranja, Engel, Sven, Kueh, Andrew J., Tai, Lin, Bachem, Annabell, Gressier, Elise, Geoghegan, Niall D., Wilcox, Stephen, Rogers, Kelly L., Garnham, Alexandra L., Dengler, Michael A., Bader, Stefanie M., Ebert, Gregor, Pearson, Jaclyn S., De Nardo, Dominic, Wang, Nancy, Yang, Chenying, Pereira, Milton, Bryant, Clare E., Strugnell, Richard A., Vince, James E., Pellegrini, Marc, Strasser, Andreas, Bedoui, Sammy, Herold, Marco J.
Published in Immunity (Cambridge, Mass.) (15.09.2020)
Published in Immunity (Cambridge, Mass.) (15.09.2020)
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Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer
Best, Sarah A., Gubser, Patrick M., Sethumadhavan, Shalini, Kersbergen, Ariena, Negrón Abril, Yashira L., Goldford, Joshua, Sellers, Katherine, Abeysekera, Waruni, Garnham, Alexandra L., McDonald, Jackson A., Weeden, Clare E., Anderson, Dovile, Pirman, David, Roddy, Thomas P., Creek, Darren J., Kallies, Axel, Kingsbury, Gillian, Sutherland, Kate D.
Published in Cell metabolism (07.06.2022)
Published in Cell metabolism (07.06.2022)
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Journal Article
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis
Sidwell, Tom, Liao, Yang, Garnham, Alexandra L., Vasanthakumar, Ajithkumar, Gloury, Renee, Blume, Jonas, Teh, Peggy P., Chisanga, David, Thelemann, Christoph, de Labastida Rivera, Fabian, Engwerda, Christian R., Corcoran, Lynn, Kometani, Kohei, Kurosaki, Tomohiro, Smyth, Gordon K., Shi, Wei, Kallies, Axel
Published in Nature communications (14.01.2020)
Published in Nature communications (14.01.2020)
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The histone lysine acetyltransferase HBO1 (KAT7) regulates hematopoietic stem cell quiescence and self-renewal
Yang, Yuqing, Kueh, Andrew J., Grant, Zoe L., Abeysekera, Waruni, Garnham, Alexandra L., Wilcox, Stephen, Hyland, Craig D., Di Rago, Ladina, Metcalf, Don, Alexander, Warren S., Coultas, Leigh, Smyth, Gordon K., Voss, Anne K., Thomas, Tim
Published in Blood (10.02.2022)
Published in Blood (10.02.2022)
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Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy
Thijssen, Rachel, Tian, Luyi, Anderson, Mary Ann, Flensburg, Christoffer, Jarratt, Andrew, Garnham, Alexandra L., Jabbari, Jafar S., Peng, Hongke, Lew, Thomas E., Teh, Charis E., Gouil, Quentin, Georgiou, Angela, Tan, Tania, Djajawi, Tirta M., Tam, Constantine S., Seymour, John F., Blombery, Piers, Gray, Daniel H.D., Majewski, Ian J., Ritchie, Matthew E., Roberts, Andrew W., Huang, David C.S.
Published in Blood (17.11.2022)
Published in Blood (17.11.2022)
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Journal Article
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth
Baell, Jonathan B., Leaver, David J., Hermans, Stefan J., Kelly, Gemma L., Brennan, Margs S., Downer, Natalie L., Nguyen, Nghi, Wichmann, Johannes, McRae, Helen M., Yang, Yuqing, Cleary, Ben, Lagiakos, H. Rachel, Mieruszynski, Stephen, Pacini, Guido, Vanyai, Hannah K., Bergamasco, Maria I., May, Rose E., Davey, Bethany K., Morgan, Kimberly J., Sealey, Andrew J., Wang, Beinan, Zamudio, Natasha, Wilcox, Stephen, Garnham, Alexandra L., Sheikh, Bilal N., Aubrey, Brandon J., Doggett, Karen, Chung, Matthew C., de Silva, Melanie, Bentley, John, Pilling, Pat, Hattarki, Meghan, Dolezal, Olan, Dennis, Matthew L., Falk, Hendrik, Ren, Bin, Charman, Susan A., White, Karen L., Rautela, Jai, Newbold, Andrea, Hawkins, Edwin D., Johnstone, Ricky W., Huntington, Nicholas D., Peat, Thomas S., Heath, Joan K., Strasser, Andreas, Parker, Michael W., Smyth, Gordon K., Street, Ian P., Monahan, Brendon J., Voss, Anne K., Thomas, Tim
Published in Nature (London) (01.08.2018)
Published in Nature (London) (01.08.2018)
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Journal Article
Necroptosis is dispensable for the development of inflammation-associated or sporadic colon cancer in mice
Alvarez-Diaz, Silvia, Preaudet, Adele, Samson, Andre L., Nguyen, Paul M., Fung, Ka Yee, Garnham, Alexandra L., Alexander, Warren S., Strasser, Andreas, Ernst, Matthias, Putoczki, Tracy L., Murphy, James M.
Published in Cell death and differentiation (01.05.2021)
Published in Cell death and differentiation (01.05.2021)
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Impaired social behaviour and molecular mediators of associated neural circuits during chronic Toxoplasma gondii infection in female mice
Tyebji, Shiraz, Seizova, Simona, Garnham, Alexandra L., Hannan, Anthony J., Tonkin, Christopher J.
Published in Brain, behavior, and immunity (01.08.2019)
Published in Brain, behavior, and immunity (01.08.2019)
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Paternal immune activation by Poly I:C modulates sperm noncoding RNA profiles and causes transgenerational changes in offspring behavior
Kleeman, Elizabeth A., Reisinger, Sonali N., Adithya, Pranav, Houston, Brendan, Stathatos, Gemma, Garnham, Alexandra L., McLaughlin, Shae, O'Bryan, Moira K., Gubert, Carolina, Hannan, Anthony J.
Published in Brain, behavior, and immunity (01.01.2024)
Published in Brain, behavior, and immunity (01.01.2024)
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The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues
Vasanthakumar, Ajithkumar, Liao, Yang, Teh, Peggy, Pascutti, Maria F., Oja, Anna E., Garnham, Alexandra L., Gloury, Renee, Tempany, Jessica C., Sidwell, Tom, Cuadrado, Eloy, Tuijnenburg, Paul, Kuijpers, Taco W., Lalaoui, Najoua, Mielke, Lisa A., Bryant, Vanessa L., Hodgkin, Philip D., Silke, John, Smyth, Gordon K., Nolte, Martijn A., Shi, Wei, Kallies, Axel
Published in Cell reports (Cambridge) (19.09.2017)
Published in Cell reports (Cambridge) (19.09.2017)
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Journal Article
Transcriptional modification of host cells harboring Toxoplasma gondii bradyzoites prevents IFN gamma-mediated cell death
Seizova, Simona, Ruparel, Ushma, Garnham, Alexandra L., Bader, Stefanie M., Uboldi, Alessandro D., Coffey, Michael J., Whitehead, Lachlan W., Rogers, Kelly L., Tonkin, Christopher J.
Published in Cell host & microbe (09.02.2022)
Published in Cell host & microbe (09.02.2022)
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Journal Article
Extracellular Vesicles in Synovial Fluid from Rheumatoid Arthritis Patients Contain miRNAs with Capacity to Modulate Inflammation
Foers, Andrew D., Garnham, Alexandra L., Chatfield, Simon, Smyth, Gordon K., Cheng, Lesley, Hill, Andrew F., Wicks, Ian P., Pang, Ken C.
Published in International journal of molecular sciences (01.05.2021)
Published in International journal of molecular sciences (01.05.2021)
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Multi-level remodelling of chromatin underlying activation of human T cells
Bediaga, Naiara G., Coughlan, Hannah D., Johanson, Timothy M., Garnham, Alexandra L., Naselli, Gaetano, Schröder, Jan, Fearnley, Liam G., Bandala-Sanchez, Esther, Allan, Rhys S., Smyth, Gordon K., Harrison, Leonard C.
Published in Scientific reports (12.01.2021)
Published in Scientific reports (12.01.2021)
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Genome-wide analysis reveals no evidence of trans chromosomal regulation of mammalian immune development
Johanson, Timothy M, Coughlan, Hannah D, Lun, Aaron T L, Bediaga, Naiara G, Naselli, Gaetano, Garnham, Alexandra L, Harrison, Leonard C, Smyth, Gordon K, Allan, Rhys S
Published in PLoS genetics (08.06.2018)
Published in PLoS genetics (08.06.2018)
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Increasing histone acetylation improves sociability and restores learning and memory in KAT6B-haploinsufficient mice
Bergamasco, Maria I, Vanyai, Hannah K, Garnham, Alexandra L, Geoghegan, Niall D, Vogel, Adam P, Eccles, Samantha, Rogers, Kelly L, Smyth, Gordon K, Blewitt, Marnie E, Hannan, Anthony J, Thomas, Tim, Voss, Anne K
Published in The Journal of clinical investigation (01.04.2024)
Published in The Journal of clinical investigation (01.04.2024)
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Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis
Potts, Margaret A., Mizutani, Shinsuke, Garnham, Alexandra L., Li Wai Suen, Connie S. N., Kueh, Andrew J., Tai, Lin, Pal, Martin, Strasser, Andreas, Herold, Marco J.
Published in Cell death and differentiation (01.06.2023)
Published in Cell death and differentiation (01.06.2023)
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G-CSF drives autoinflammation in APLAID
Mulazzani, Elisabeth, Kong, Klara, Aróstegui, Juan I., Ng, Ashley P., Ranathunga, Nishika, Abeysekera, Waruni, Garnham, Alexandra L., Ng, Sze-Ling, Baker, Paul J., Jackson, Jacob T., Lich, John D., Hibbs, Margaret L., Wicks, Ian P., Louis, Cynthia, Masters, Seth L.
Published in Nature immunology (01.05.2023)
Published in Nature immunology (01.05.2023)
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Suv39h-catalyzed H3K9me3 is critical for euchromatic genome organization and the maintenance of gene transcription
Keenan, Christine R, Coughlan, Hannah D, Iannarella, Nadia, Tapia Del Fierro, Andres, Keniry, Andrew, Johanson, Timothy M, Chan, Wing Fuk, Garnham, Alexandra L, Whitehead, Lachlan W, Blewitt, Marnie E, Smyth, Gordon K, Allan, Rhys S
Published in Genome research (01.04.2024)
Published in Genome research (01.04.2024)
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Extracellular vesicles from early stage Plasmodium falciparum‐infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes
Sampaio, Natália G., Emery, Samantha J., Garnham, Alexandra L., Tan, Qiao Y., Sisquella, Xavier, Pimentel, Matthew A., Jex, Aaron R., Regev‐Rudzki, Neta, Schofield, Louis, Eriksson, Emily M.
Published in Cellular microbiology (01.05.2018)
Published in Cellular microbiology (01.05.2018)
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