Phase I dose‐escalation trial investigating volasertib as monotherapy or in combination with cytarabine in patients with relapsed/refractory acute myeloid leukaemia
Ottmann, Oliver G., Müller‐Tidow, Carsten, Krämer, Alwin, Schlenk, Richard F., Lübbert, Michael, Bug, Gesine, Krug, Utz, Bochtler, Tilmann, Voss, Florian, Taube, Tillmann, Liu, Dan, Garin‐Chesa, Pilar, Döhner, Hartmut
Published in British journal of haematology (01.03.2019)
Published in British journal of haematology (01.03.2019)
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Comprehensive analysis of the ErbB receptor family in pediatric nervous system tumors and rhabdomyosarcoma
Varlet, Pascale, Bouffet, Eric, Casanova, Michela, Giangaspero, Felice, Antonelli, Manila, Hargrave, Darren, Ladenstein, Ruth, Pearson, Andy, Hawkins, Cynthia, König, Fatima Barbara, Rüschoff, Josef, Schmauch, Christian, Bühnemann, Claudia, Garin‐Chesa, Pilar, Schweifer, Norbert, Uttenreuther‐Fischer, Martina, Gibson, Neil, Ittrich, Carina, Krämer, Nicole, Solca, Flavio, Stolze, Britta, Geoerger, Birgit
Published in Pediatric blood & cancer (01.01.2022)
Published in Pediatric blood & cancer (01.01.2022)
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The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy
Sanderson, Michael P, Hofmann, Marco H, Garin-Chesa, Pilar, Schweifer, Norbert, Wernitznig, Andreas, Fischer, Stefan, Jeschko, Astrid, Meyer, Reiner, Moll, Jürgen, Pecina, Thomas, Arnhof, Heribert, Weyer-Czernilofsky, Ulrike, Zahn, Stephan K, Adolf, Günther R, Kraut, Norbert
Published in Molecular cancer therapeutics (01.10.2017)
Published in Molecular cancer therapeutics (01.10.2017)
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hGPR87 contributes to viability of human tumor cells
Glatt, Sebastian, Halbauer, Daniel, Heindl, Stefan, Wernitznig, Andreas, Kozina, Daniela, Su, Kuan‐Chung, Puri, Christina, Garin‐Chesa, Pilar, Sommergruber, Wolfgang
Published in International journal of cancer (01.05.2008)
Published in International journal of cancer (01.05.2008)
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Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors
Schütte, Moritz, Risch, Thomas, Abdavi-Azar, Nilofar, Boehnke, Karsten, Schumacher, Dirk, Keil, Marlen, Yildiriman, Reha, Jandrasits, Christine, Borodina, Tatiana, Amstislavskiy, Vyacheslav, Worth, Catherine L., Schweiger, Caroline, Liebs, Sandra, Lange, Martin, Warnatz, Hans- Jörg, Butcher, Lee M., Barrett, James E., Sultan, Marc, Wierling, Christoph, Golob-Schwarzl, Nicole, Lax, Sigurd, Uranitsch, Stefan, Becker, Michael, Welte, Yvonne, Regan, Joseph Lewis, Silvestrov, Maxine, Kehler, Inge, Fusi, Alberto, Kessler, Thomas, Herwig, Ralf, Landegren, Ulf, Wienke, Dirk, Nilsson, Mats, Velasco, Juan A., Garin-Chesa, Pilar, Reinhard, Christoph, Beck, Stephan, Schäfer, Reinhold, Regenbrecht, Christian R. A., Henderson, David, Lange, Bodo, Haybaeck, Johannes, Keilholz, Ulrich, Hoffmann, Jens, Lehrach, Hans, Yaspo, Marie-Laure
Published in Nature communications (10.02.2017)
Published in Nature communications (10.02.2017)
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Triple Angiokinase Inhibitor Nintedanib Directly Inhibits Tumor Cell Growth and Induces Tumor Shrinkage via Blocking Oncogenic Receptor Tyrosine Kinases
Hilberg, Frank, Tontsch-Grunt, Ulrike, Baum, Anke, Le, Anh T, Doebele, Robert C, Lieb, Simone, Gianni, Davide, Voss, Tilman, Garin-Chesa, Pilar, Haslinger, Christian, Kraut, Norbert
Published in The Journal of pharmacology and experimental therapeutics (01.03.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2018)
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Journal Article
BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity
RUDOLPH, Dorothea, STEEGMAIER, Martin, HOFFMANN, Matthias, GRAUERT, Matthias, BAUM, Anke, QUANT, Jens, HASLINGER, Christian, GARIN-CHESA, Pilar, ADOLF, Gunther R
Published in Clinical cancer research (01.05.2009)
Published in Clinical cancer research (01.05.2009)
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Journal Article
Expression of stromal cell markers in distinct compartments of human skin cancers
Huber, Margit A., Kraut, Norbert, Schweifer, Norbert, Dolznig, Helmut, Peter, Ralf U., Schubert, Roland D., Scharffetter-Kochanek, Karin, Pehamberger, Hubert, Garin-Chesa, Pilar
Published in Journal of cutaneous pathology (01.02.2006)
Published in Journal of cutaneous pathology (01.02.2006)
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Journal Article
BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo
Steegmaier, Martin, Hoffmann, Matthias, Baum, Anke, Lénárt, Péter, Petronczki, Mark, Krššák, Martin, Gürtler, Ulrich, Garin-Chesa, Pilar, Lieb, Simone, Quant, Jens, Grauert, Matthias, Adolf, Günther R., Kraut, Norbert, Peters, Jan-Michael, Rettig, Wolfgang J.
Published in Current biology (20.02.2007)
Published in Current biology (20.02.2007)
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Volasertib Versus Chemotherapy in Platinum-Resistant or -Refractory Ovarian Cancer: A Randomized Phase II Groupe des Investigateurs Nationaux pour l'Etude des Cancers de l'Ovaire Study
Pujade-Lauraine, Eric, Selle, Frédéric, Weber, Béatrice, Ray-Coquard, Isabelle-Laure, Vergote, Ignace, Sufliarsky, Jozef, Del Campo, Josep Maria, Lortholary, Alain, Lesoin, Anne, Follana, Philippe, Freyer, Gilles, Pardo, Beatriz, Vidal, Laura, Tholander, Bengt, Gladieff, Laurence, Sassi, Mouna, Garin-Chesa, Pilar, Nazabadioko, Serge, Marzin, Kristell, Pilz, Korinna, Joly, Florence
Published in Journal of clinical oncology (01.03.2016)
Published in Journal of clinical oncology (01.03.2016)
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Journal Article
Effective Immunoconjugate Therapy in Cancer Models Targeting a Serine Protease of Tumor Fibroblasts
Ostermann, Elinborg, Garin-Chesa, Pilar, Heider, Karl Heinz, Kalat, Milena, Lamche, Herbert, Puri, Christina, Kerjaschki, Dontscho, Rettig, Wolfgang J., Adolf, Guenther R.
Published in Clinical cancer research (15.07.2008)
Published in Clinical cancer research (15.07.2008)
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Journal Article
Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia
Rudolph, Dorothea, Impagnatiello, Maria Antonietta, Blaukopf, Claudia, Sommer, Christoph, Gerlich, Daniel W, Roth, Mareike, Tontsch-Grunt, Ulrike, Wernitznig, Andreas, Savarese, Fabio, Hofmann, Marco H, Albrecht, Christoph, Geiselmann, Lena, Reschke, Markus, Garin-Chesa, Pilar, Zuber, Johannes, Moll, Jürgen, Adolf, Günther R, Kraut, Norbert
Published in The Journal of pharmacology and experimental therapeutics (01.03.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2015)
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Journal Article
A randomized, open‐label, phase I/II trial to investigate the maximum tolerated dose of the Polo‐like kinase inhibitor BI 2536 in elderly patients with refractory/relapsed acute myeloid leukaemia
Müller‐Tidow, Carsten, Bug, Gesine, Lübbert, Michael, Krämer, Alwin, Krauter, Jürgen, Valent, Peter, Nachbaur, David, Berdel, Wolfgang E., Ottmann, Oliver G., Fritsch, Holger, Munzert, Gerd, Garin‐Chesa, Pilar, Fleischer, Frank, Taube, Tillmann, Döhner, Hartmut
Published in British journal of haematology (01.10.2013)
Published in British journal of haematology (01.10.2013)
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Journal Article
Efficacy of the highly selective focal adhesion kinase inhibitor BI 853520 in adenocarcinoma xenograft models is linked to a mesenchymal tumor phenotype
Hirt, Ulrich A., Waizenegger, Irene C., Schweifer, Norbert, Haslinger, Christian, Gerlach, Daniel, Braunger, Jürgen, Weyer-Czernilofsky, Ulrike, Stadtmüller, Heinz, Sapountzis, Ioannis, Bader, Gerd, Zoephel, Andreas, Bister, Bojan, Baum, Anke, Quant, Jens, Kraut, Norbert, Garin-Chesa, Pilar, Adolf, Günther R.
Published in Oncogenesis (New York, NY) (23.02.2018)
Published in Oncogenesis (New York, NY) (23.02.2018)
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A highly selective telomerase inhibitor limiting human cancer cell proliferation
Damm, Klaus, Hemmann, Ulrike, Garin-Chesa, Pilar, Hauel, Norbert, Kauffmann, Iris, Priepke, Henning, Niestroj, Claudia, Daiber, Christine, Enenkel, Barbara, Guilliard, Bernd, Lauritsch, Ines, Müller, Elfriede, Pascolo, Emanuelle, Sauter, Gabriele, Pantic, Milena, Martens, Uwe M., Wenz, Christian, Lingner, Joachim, Kraut, Norbert, Rettig, Wolfgang J., Schnapp, Andreas
Published in The EMBO journal (17.12.2001)
Published in The EMBO journal (17.12.2001)
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Journal Article
Alveolar soft‐part sarcoma. A clinico‐pathologic study of half a century
Lieberman, Philip H., Brennan, Murray F., Kimmel, Marek, Erlandson, Robert A., Garin‐Chesa, Pilar, Flehinger, Betty Y.
Published in Cancer (01.01.1989)
Published in Cancer (01.01.1989)
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Journal Article
Mechanism of Human Telomerase Inhibition by BIBR1532, a Synthetic, Non-nucleosidic Drug Candidate
Pascolo, Emanuelle, Wenz, Christian, Lingner, Joachim, Hauel, Norbert, Priepke, Henning, Kauffmann, Iris, Garin-Chesa, Pilar, Rettig, Wolfgang J., Damm, Klaus, Schnapp, Andreas
Published in The Journal of biological chemistry (03.05.2002)
Published in The Journal of biological chemistry (03.05.2002)
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Journal Article
Molecular characterization of the desmoplastic tumor stroma in medullary thyroid carcinoma
KOPEREK, Oskar, SCHEUBA, Christian, PURI, Christina, BIRNER, Peter, HASLINGER, Christian, RETTIG, Wolfgang, NIEDERLE, Bruno, KASERER, Klaus, GARIN CHESAI, Pilar
Published in International journal of oncology (01.07.2007)
Published in International journal of oncology (01.07.2007)
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Journal Article
Mouse fibroblast activation protein: Molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers
Niedermeyer, Joachim, Scanlan, Matthew J., Garin‐Chesa, Pilar, Daiber, Christine, Fiebig, Heinz H., Old, Lloyd J., Rettig, Wolfgang J., Schnapp, Andreas
Published in International journal of cancer (02.05.1997)
Published in International journal of cancer (02.05.1997)
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