Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin
Florence, Gordon J, Gardner, Nicola M, Paterson, Ian
Published in Natural product reports (01.01.2008)
Published in Natural product reports (01.01.2008)
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Journal Article
The Bound Conformation of Microtubule-Stabilizing Agents: NMR Insights into the Bioactive 3D Structure of Discodermolide and Dictyostatin
Canales, Angeles, Matesanz, Ruth, Gardner, Nicola M., Andreu, José Manuel, Paterson, Ian, Díaz, J. Fernando, Jiménez-Barbero, Jesús
Published in Chemistry : a European journal (28.08.2008)
Published in Chemistry : a European journal (28.08.2008)
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Journal Article
Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells
Trigili, Chiara, Barasoain, Isabel, Sánchez-Murcia, Pedro A, Bargsten, Katja, Redondo-Horcajo, Mariano, Nogales, Aurora, Gardner, Nicola M, Meyer, Arndt, Naylor, Guy J, Gómez-Rubio, Elena, Gago, Federico, Steinmetz, Michel O, Paterson, Ian, Prota, Andrea E, Díaz, J. Fernando
Published in ACS omega (31.12.2016)
Published in ACS omega (31.12.2016)
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Journal Article
Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol
Paterson, Ian, Naylor, Guy J, Gardner, Nicola M, Guzmán, Esther, Wright, Amy E
Published in Chemistry, an Asian journal (01.02.2011)
Published in Chemistry, an Asian journal (01.02.2011)
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Journal Article
Synthesis and biological evaluation of novel analogues of dictyostatin
Paterson, Ian, Gardner, Nicola M., Poullennec, Karine G., Wright, Amy E.
Published in Bioorganic & medicinal chemistry letters (01.05.2007)
Published in Bioorganic & medicinal chemistry letters (01.05.2007)
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Journal Article
Total synthesis and biological evaluation of novel C2–C6 region analogues of dictyostatin
Paterson, Ian, Gardner, Nicola M., Guzmán, Esther, Wright, Amy E.
Published in Bioorganic & medicinal chemistry (15.03.2009)
Published in Bioorganic & medicinal chemistry (15.03.2009)
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Journal Article
MT-Stabilizer, Dictyostatin, Exhibits Prolonged Brain Retention and Activity: Potential Therapeutic Implications
Brunden, Kurt R, Gardner, Nicola M, James, Michael J, Yao, Yuemang, Trojanowski, John Q, Lee, Virginia M.-Y, Paterson, Ian, Ballatore, Carlo, Smith, Amos B
Published in ACS medicinal chemistry letters (12.09.2013)
Published in ACS medicinal chemistry letters (12.09.2013)
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Journal Article
Total synthesis of novel dictyostatin analogs and hybrids as microtubule-stabilizing anticancer agents
Paterson, Ian, Gardner, Nicola M., Naylor, Guy J.
Published in Pure and applied chemistry (01.01.2009)
Published in Pure and applied chemistry (01.01.2009)
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Journal Article
Synthesis and Biological Evaluation of 10,11-Dihydrodictyostatin, a Potent Analogue of the Marine Anticancer Agent Dictyostatin
Paterson, Ian, Gardner, Nicola M, Poullennec, Karine G, Wright, Amy E
Published in Journal of natural products (Washington, D.C.) (01.03.2008)
Published in Journal of natural products (Washington, D.C.) (01.03.2008)
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Journal Article
Total synthesis of (-)-dictyostatin, a microtubule-stabilising anticancer macrolide of marine sponge origin: 2009 Tetrahedron Prize for Creativity in Organic Chemistry: Adventures in Organic Synthesis: Steven V. Ley
PATERSON, Ian, BRITTON, Robert, DELGADO, Oscar, GARDNER, Nicola M, MEYER, Arndt, NAYLOR, Guy J, POULLENNEC, Karine G
Published in Tetrahedron (2010)
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Published in Tetrahedron (2010)
Journal Article
Synthesis and Biological Evaluation of 10,11-Dihydrodictyostatin, a Potent Analogue of the Marine Anticancer Agent Dictyostatin super([section])
Gardner, Nicola M, Paterson, Ian, Wright, Amy E, Poullennec, Karine G
Published in Journal of natural products (Washington, D.C.) (01.01.2008)
Published in Journal of natural products (Washington, D.C.) (01.01.2008)
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Journal Article