Vitamin C Antagonizes the Cytotoxic Effects of Antineoplastic Drugs
HEANEY, Mark L, GARDNER, Jeffrey R, KARASAVVAS, Nicos, GOLDE, David W, SCHEINBERG, David A, SMITH, Emily A, O'CONNOR, Owen A
Published in Cancer research (Chicago, Ill.) (01.10.2008)
Published in Cancer research (Chicago, Ill.) (01.10.2008)
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Journal Article
Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia
Leeksma, Alexander C., Taylor, Justin, Wu, Bian, Gardner, Jeffrey R., He, Jie, Nahas, Michelle, Gonen, Mithat, Alemayehu, Wendimagegn G., te Raa, Doreen, Walther, Tatjana, Hüllein, Jennifer, Dietrich, Sascha, Claus, Rainer, de Boer, Fransien, de Heer, Koen, Dubois, Julie, Dampmann, Maria, Dürig, Jan, van Oers, Marinus H. J., Geisler, Christian H., Eldering, Eric, Levine, Ross L., Miller, Vincent, Mughal, Tariq, Lamanna, Nicole, Frattini, Mark G., Heaney, Mark L., Zelenetz, Andrew, Zenz, Thorsten, Abdel-Wahab, Omar, Kater, Arnon P.
Published in Leukemia (01.02.2019)
Published in Leukemia (01.02.2019)
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Journal Article
Synthesis and Preclinical Evaluation of QS-21 Variants Leading to Simplified Vaccine Adjuvants and Mechanistic Probes
Chea, Eric K, Fernández-Tejada, Alberto, Damani, Payal, Adams, Michelle M, Gardner, Jeffrey R, Livingston, Philip O, Ragupathi, Govind, Gin, David Y
Published in Journal of the American Chemical Society (15.08.2012)
Published in Journal of the American Chemical Society (15.08.2012)
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Journal Article
Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer
Ragupathi, Govind, Gardner, Jeffrey R, Livingston, Philip O, Gin, David Y
Published in Expert review of vaccines (01.04.2011)
Published in Expert review of vaccines (01.04.2011)
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Journal Article
A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia
Mallikaratchy, Prabodhika R, Ruggiero, Alessandro, Gardner, Jeffrey R, Kuryavyi, Vitaly, Maguire, William F, Heaney, Mark L, McDevitt, Michael R, Patel, Dinshaw J, Scheinberg, David A
Published in Nucleic acids research (01.03.2011)
Published in Nucleic acids research (01.03.2011)
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Journal Article
Development of a minimal saponin vaccine adjuvant based on QS-21
Fernández-Tejada, Alberto, Chea, Eric K., George, Constantine, Pillarsetty, NagaVaraKishore, Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Lewis, Jason S., Tan, Derek S., Gin, David Y.
Published in Nature chemistry (01.07.2014)
Published in Nature chemistry (01.07.2014)
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Journal Article
Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma
Paoluzzi, Luca, Gonen, Mithat, Gardner, Jeffrey R., Mastrella, Jill, Yang, Dajun, Holmlund, Jon, Sorensen, Mel, Leopold, Lance, Manova, Katia, Marcucci, Guido, Heaney, Mark L., O’Connor, Owen A.
Published in Blood (01.06.2008)
Published in Blood (01.06.2008)
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Journal Article
The BH3-only mimetic ABT-737 synergizes the antineoplastic activity of proteasome inhibitors in lymphoid malignancies
Paoluzzi, Luca, Gonen, Mithat, Bhagat, Govind, Furman, Richard R., Gardner, Jeffrey R., Scotto, Luigi, Gueorguiev, Volodia D., Heaney, Mark L., Manova, Katia, O'Connor, Owen A.
Published in Blood (01.10.2008)
Published in Blood (01.10.2008)
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Journal Article
Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol
Fernández-Tejada, Alberto, Chea, Eric K., George, Constantine, Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Tan, Derek S., Gin, David Y.
Published in Bioorganic & medicinal chemistry (01.11.2014)
Published in Bioorganic & medicinal chemistry (01.11.2014)
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Journal Article
Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis
Koppikar, Priya, Abdel-Wahab, Omar, Hedvat, Cyrus, Marubayashi, Sachie, Patel, Jay, Goel, Aviva, Kucine, Nicole, Gardner, Jeffrey R., Combs, Andrew P., Vaddi, Kris, Haley, Patrick J., Burn, Timothy C., Rupar, Mark, Bromberg, Jacqueline F., Heaney, Mark L., de Stanchina, Elisa, Fridman, Jordan S., Levine, Ross L.
Published in Blood (08.04.2010)
Published in Blood (08.04.2010)
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Journal Article
Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics
Lee, Mona D, She, Yuhong, Soskis, Michael J, Borella, Christopher P, Gardner, Jeffrey R, Hayes, Paula A, Dy, Benzon M, Heaney, Mark L, Philips, Mark R, Bornmann, William G, Sirotnak, Francis M, Scheinberg, David A
Published in The Journal of clinical investigation (01.10.2004)
Published in The Journal of clinical investigation (01.10.2004)
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Journal Article
The Warburg Effect Confers Adverse Outcome in Chronic Lymphocytic Leukemia
Gardner, Jeffrey R, Devlin, Sean M, Knapp, Kristina, Bauli, Francesco, Patel, Minal, Lamanna, Nicole, Frattini, Mark G, Brentjens, Renier, Maslak, Peter, Jurcic, Joseph G, Weiss, Mark A, Abdel-Wahab, Omar, Scheinberg, David A, Heaney, Mark L
Published in Clinical lymphoma, myeloma and leukemia (01.09.2014)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2014)
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Journal Article
MINIMAL SAPONIN ANALOGUES SYNTHESIS AND USE THEREOF
PILLARSETTY NAGAVARAKISHORE, CHEA ERIC K, TAN DEREK S, LEWIS JASON S, GIN DAVID Y, FERNANDEZ TEJADA ALBERTO, GARDNER JEFFREY R
Year of Publication 22.03.2017
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Year of Publication 22.03.2017
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Heaney, Mark L., Gardner, Jeffrey R., O'Connor, Owen A.
Published in Cancer research (Chicago, Ill.) (15.11.2009)
Published in Cancer research (Chicago, Ill.) (15.11.2009)
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Journal Article
Genomic Analysis of Serial Samples from CLL Patients Identifies Clonal Events Associated with Disease Progression
Gardner, Jeffrey R, Nahas, Michelle, He, Jie, Aumann, Shlomzion, Gonen, Mithat, Patel, Minal, Knapp, Kristina M., Palomba, Maria Lia, Yelensky, Roman, Donahue, Amy L, Otto, Geoff, Arcila, Maria, Lamanna, Nicole, Frattini, Mark G., Dogan, Ahmet, Park, Jae H, Lipson, Doron, Tallman, Martin S., Levine, Ross L., Stephens, Philip J., van den Brink, Marcel R.M., Heaney, Mark L, Miller, Vincent A., Zelenetz, Andrew D., Abdel-Wahab, Omar
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Elevated Mitochondrial Membrane Potential in CLL Cells Is Associated with a more aggressive Natural History
Gardner, Jeffrey R, Knapp, Kristina, Frattini, Mark G., Lamanna, Nicole, Brentjens, Renier, Jurcic, Joseph G, Maslak, Peter G., Berman, Ellin, Weiss, Mark, Scheinberg, David A., Heaney, Mark
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
Aerobic Glycolysis Predicts Outcome in Early Chronic Lymphocytic Leukemia
Gardner, Jeffrey R, Devlin, Sean, Knapp, Kristina, Bauli, Francesco, Lamanna, Nicole, Frattini, Mark G., Brentjens, Renier J, Maslak, Peter G., Jurcic, Joseph G., Weiss, Mark, Scheinberg, David A., Heaney, Mark
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Extensive High-Depth Sequencing Of Longitudinal CLL Samples Identifies Frequent Mutations In MAP Kinase Signaling and Novel Mutations Activating Notch and Beta-Catenin
Gardner, Jeffrey R, Nahas, Michelle K., He, Jie, Patel, Minal, Knapp, Kristina M., Palomba, M. Lia, Yelensky, Roman, Donahue, Amy L, Otto, Geoff A., Arcila, Maria, Dogan, Ahmet, Park, Jae H, Zelenetz, Andrew D., Lipson, Doron, Tallman, Martin S., Levine, Ross L., Stephens, Philip J., van den Brink, Marcel R.M., Miller, Vincent A., Heaney, Mark L, Abdel-Wahab, Omar
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
High Mitochondrial Membrane Potential Identifies Patients with Myeloproliferative Neoplasms with a More Aggressive Natural History
Gardner, Jeffrey R, Abdel-Wahab, Omar, Frattini, Mark, Jurcic, Joseph G, Knapp, Kristina, Rosenblat, Todd L., Soff, Gerald A., Levine, Ross, Heaney, Mark
Published in Blood (19.11.2010)
Published in Blood (19.11.2010)
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