Induction of Migraine-Like Photophobic Behavior in Mice by Both Peripheral and Central CGRP Mechanisms
Mason, Bianca N, Kaiser, Eric A, Kuburas, Adisa, Loomis, Maria-Cristina M, Latham, John A, Garcia-Martinez, Leon F, Russo, Andrew F
Published in The Journal of neuroscience (04.01.2017)
Published in The Journal of neuroscience (04.01.2017)
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Repetitive stress in mice causes migraine-like behaviors and calcitonin gene-related peptide-dependent hyperalgesic priming to a migraine trigger
Avona, Amanda, Mason, Bianca N, Lackovic, Jacob, Wajahat, Naureen, Motina, Marina, Quigley, Lilyana, Burgos-Vega, Carolina, Moldovan Loomis, Cristina, Garcia-Martinez, Leon F, Akopian, Armen N, Price, Theodore J, Dussor, Gregory
Published in Pain (Amsterdam) (01.11.2020)
Published in Pain (Amsterdam) (01.11.2020)
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Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase-Activating Peptide
Moldovan Loomis, Cristina, Dutzar, Benjamin, Ojala, Ethan W, Hendrix, Lee, Karasek, Charlie, Scalley-Kim, Michelle, Mulligan, Jenny, Fan, Pei, Billgren, Jens, Rubin, Vanessa, Boshaw, Heidi, Kwon, Gayle, Marzolf, Sam, Stewart, Erica, Jurchen, David, Pederson, Susan M, Perrino McCulloch, Lisa, Baker, Brian, Cady, Roger K, Latham, John A, Allison, Dan, Garcia-Martinez, Leon F
Published in The Journal of pharmacology and experimental therapeutics (01.04.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2019)
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A Female-Specific Role for Calcitonin Gene-Related Peptide (CGRP) in Rodent Pain Models
Paige, Candler, Plasencia-Fernandez, Isabel, Kume, Moeno, Papalampropoulou-Tsiridou, Melina, Lorenzo, Louis-Etienne, David, Eric T, He, Lucy, Mejia, Galo L, Driskill, Christopher, Ferrini, Francesco, Feldhaus, Andrew L, Garcia-Martinez, Leon F, Akopian, Armen N, De Koninck, Yves, Dussor, Gregory, Price, Theodore J
Published in The Journal of neuroscience (09.03.2022)
Published in The Journal of neuroscience (09.03.2022)
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PACAP Induces Light Aversion in Mice by an Inheritable Mechanism Independent of CGRP
Kuburas, Adisa, Mason, Bianca N, Hing, Benjamin, Wattiez, Anne-Sophie, Reis, Alyssa S, Sowers, Levi P, Moldovan Loomis, Cristina, Garcia-Martinez, Leon F, Russo, Andrew F
Published in The Journal of neuroscience (26.05.2021)
Published in The Journal of neuroscience (26.05.2021)
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Peripherally administered calcitonin gene-related peptide induces spontaneous pain in mice: implications for migraine
Rea, Brandon J, Wattiez, Anne-Sophie, Waite, Jayme S, Castonguay, William C, Schmidt, Chantel M, Fairbanks, Aaron M, Robertson, Bennett R, Brown, Cameron J, Mason, Bianca N, Moldovan-Loomis, Maria-Cristina, Garcia-Martinez, Leon F, Poolman, Pieter, Ledolter, Johannes, Kardon, Randy H, Sowers, Levi P, Russo, Andrew F
Published in Pain (Amsterdam) (01.11.2018)
Published in Pain (Amsterdam) (01.11.2018)
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Pharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related Peptide
Garcia-Martinez, Leon F, Raport, Carol J, Ojala, Ethan W, Dutzar, Benjamin, Anderson, Katie, Stewart, Erica, Kovacevich, Brian, Baker, Brian, Billgren, Jens, Scalley-Kim, Michelle, Karasek, Charlie, Allison, Dan, Latham, John A
Published in The Journal of pharmacology and experimental therapeutics (01.07.2020)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2020)
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Journal Article
Anti-CGRP antibodies block CGRP-induced diarrhea in mice
Kaiser, Eric A, Rea, Brandon J, Kuburas, Adisa, Kovacevich, Brian R, Garcia-Martinez, Leon F, Recober, Ana, Russo, Andrew F
Published in Neuropeptides (Edinburgh) (01.08.2017)
Published in Neuropeptides (Edinburgh) (01.08.2017)
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ALD1613, A Novel Long-Acting Monoclonal Antibody to Control ACTH-Driven Pharmacology
Feldhaus, Andrew L, Anderson, Katie, Dutzar, Benjamin, Ojala, Ethan, McNeill, Patricia Dianne, Fan, Pei, Mulligan, Jenny, Marzolf, Sam, Karasek, Charlie, Scalley-Kim, Michelle, Stewart, Erica, Billgren, Jens, Rubin, Vanessa, Schneider, Kathleen, Jurchen, David, Snow, Kathy, Barnett, Shaun, Bengtsson, Barbara, Baker, Brian, Latham, John A, Allison, Dan, Garcia-Martinez, Leon F
Published in Endocrinology (Philadelphia) (01.01.2017)
Published in Endocrinology (Philadelphia) (01.01.2017)
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CGRP USE OF ANTI-CGRP ANTIBODIES AND ANTIBODY FRAGMENTS TO PREVENT OR INHIBIT PHOTOPHOBIA OR LIGHT AVERSION IN SUBJECTS IN NEED THEREOF ESPECIALLY MIGRAINE SUFFERERS
SMITH JEFFREY T.L, RUSSO ANDREW F, KUBURAS ADISA, KOVACEVICH BRIAN ROBERT, GARCIA MARTINEZ LEON F, KAISER ERIC A, LATHAM JOHN A, RECOBER ANA, RADDANT ANN C
Year of Publication 05.04.2019
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Year of Publication 05.04.2019
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ANTI-NGF COMPOSITIONS AND USE THEREOF
GARCIA MARTINEZ LEON F, CHANG BETTY YU CHING, LATHAM JOHN A, AKATSUKA CORINNE C, DUTZAR BENJAMIN H, FAN PEI, SMITH JEFFREY T.L, BILLGREN JENS, STEWART ERICA A, OJALA ETHAN W, MCNEILL PATRICIA DIANNE, KOVACEVICH BRIAN R, MITCHELL DANIELLE M
Year of Publication 02.10.2019
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Year of Publication 02.10.2019
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항-PACAP 항체 및 그의 용도
GARCIA MARTINEZ LEON F, MULLIGAN JENNY, BILLGREN JENS J, LATHAM JOHN A, RUBIN VANESSA LISBETH, LOOMIS MARIA CRISTINA, DUTZAR BENJAMIN H, KARASEK CHARLIE, ALLISON DANIEL S, FAN PEI, OJALA ETHAN, SMITH JEFFREY T.L, STEWART ERICA, HENDRIX KATHERINE LEE, SCALLEY KIM MICHELLE
Year of Publication 16.01.2019
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Year of Publication 16.01.2019
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인간화 항-PACAP 항체 및 그의 용도
GARCIA MARTINEZ LEON F, MULLIGAN JENNY, BILLGREN JENS J, LATHAM JOHN A, RUBIN VANESSA LISBETH, LOOMIS MARIA CRISTINA, DUTZAR BENJAMIN H, KARASEK CHARLIE, ALLISON DANIEL S, FAN PEI, OJALA ETHAN, SMITH JEFFREY T.L, STEWART ERICA, HENDRIX KATHERINE LEE, SCALLEY KIM MICHELLE
Year of Publication 16.01.2019
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Year of Publication 16.01.2019
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ANTIBODIES TO HGF AND COMPOSITIONS CONTAINING
ANDERSON KATIE, GARCIA MARTINEZ LEON F, KOVACEVICH BRIAN R, LATHAM JOHN A, FELDHAUS ANDREW L, DUTZAR BENJAMIN H
Year of Publication 16.12.2015
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Year of Publication 16.12.2015
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PROTOCOL FOR IDENTIFYING AND ISOLATING ANTIGEN-SPECIFIC B CELLS AND PRODUCING ANTIBODIES TO DESIRED ANTIGENS
JENSEN ANNE ELISABETH CARVALHO, GARCIA MARTINEZ LEON F, ANDERSON KATIE, BILLGREN JENS, OJALA ETHAN W, LATHAM JOHN A, DUTZAR BENJAMIN H, ALLISON DANIEL S
Year of Publication 16.12.2015
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Year of Publication 16.12.2015
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MULTI-COPY STRATEGY FOR HIGH-TITER AND HIGH-PURITY PRODUCTION OF MULTI-SUBUNIT PROTEINS SUCH AS ANTIBODIES IN TRANSFORMED MICROBES SUCH AS PICHIA PASTORIS
LATHAM JOHN, MITCHELL DANIELLE MARIE, GARCIA MARTINEZ LEON F, MCNEILL PATRICIA DIANNE, OJALA ETHAN WAYNE, INAN MEHMET
Year of Publication 13.05.2014
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Year of Publication 13.05.2014
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USE OF ANTI-CGRP OR ANTI-CGRP-R ANTIBODIES OR ANTIBODY FRAGMENTS TO TREAT OR PREVENT CHRONIC AND ACUTE FORMS OF DIARRHEA
SMITH JEFFREY T.L, RUSSO ANDREW F, KUBURAS ADISA, KOVACEVICH BRIAN ROBERT, GARCIA MARTINEZ LEON F, KAISER ERIC A, LATHAM JOHN A, RECOBER ANA, RADDANT ANN C
Year of Publication 19.06.2014
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Year of Publication 19.06.2014
Patent
USE OF ANTI-CGRP ANTIBODIES AND ANTIBODY FRAGMENTS TO PREVENT OR INHIBIT PHOTOPHOBIA OR LIGHT AVERSION IN SUBJECTS IN NEED THEREOF, ESPECIALLY MIGRAINE SUFFERERS
SMITH JEFFREY T.L, RUSSO ANDREW F, KUBURAS ADISA, KOVACEVICH BRIAN ROBERT, GARCIA MARTINEZ LEON F, KAISER ERIC A, LATHAM JOHN A, RECOBER ANA, RADDANT ANN C
Year of Publication 23.04.2014
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Year of Publication 23.04.2014
Patent