Glycerol-3-phosphate acyltranferase-2 behaves as a cancer testis gene and promotes growth and tumorigenicity of the breast cancer MDA-MB-231 cell line
Pellon-Maison, Magali, Montanaro, Mauro A, Lacunza, Ezequiel, Garcia-Fabiani, Maria B, Soler-Gerino, Mercedes C, Cattaneo, Elizabeth R, Quiroga, Ivana Y, Abba, Martin C, Coleman, Rosalind A, Gonzalez-Baro, Maria R
Published in PloS one (26.06.2014)
Published in PloS one (26.06.2014)
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IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response
Núñez, Felipe J, Mendez, Flor M, Kadiyala, Padma, Alghamri, Mahmoud S, Savelieff, Masha G, Garcia-Fabiani, Maria B, Haase, Santiago, Koschmann, Carl, Calinescu, Anda-Alexandra, Kamran, Neha, Saxena, Meghna, Patel, Rohin, Carney, Stephen, Guo, Marissa Z, Edwards, Marta, Ljungman, Mats, Qin, Tingting, Sartor, Maureen A, Tagett, Rebecca, Venneti, Sriram, Brosnan-Cashman, Jacqueline, Meeker, Alan, Gorbunova, Vera, Zhao, Lili, Kremer, Daniel M, Zhang, Li, Lyssiotis, Costas A, Jones, Lindsey, Herting, Cameron J, Ross, James L, Hambardzumyan, Dolores, Hervey-Jumper, Shawn, Figueroa, Maria E, Lowenstein, Pedro R, Castro, Maria G
Published in Science translational medicine (13.02.2019)
Published in Science translational medicine (13.02.2019)
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H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models
Haase, Santiago, Banerjee, Kaushik, Mujeeb, Anzar A, Hartlage, Carson S, Núñez, Fernando M, Núñez, Felipe J, Alghamri, Mahmoud S, Kadiyala, Padma, Carney, Stephen, Barissi, Marcus N, Taher, Ayman W, Brumley, Emily K, Thompson, Sarah, Dreyer, Justin T, Alindogan, Caitlin T, Garcia-Fabiani, Maria B, Comba, Andrea, Venneti, Sriram, Ravikumar, Visweswaran, Koschmann, Carl, Carcaboso, Ángel M, Vinci, Maria, Rao, Arvind, Yu, Jennifer S, Lowenstein, Pedro R, Castro, Maria G
Published in The Journal of clinical investigation (15.11.2022)
Published in The Journal of clinical investigation (15.11.2022)
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Epigenetic reprogramming and chromatin accessibility in pediatric diffuse intrinsic pontine gliomas: a neural developmental disease
Mendez, Flor M, Núñez, Felipe J, Garcia-Fabiani, Maria B, Haase, Santiago, Carney, Stephen, Gauss, Jessica C, Becher, Oren J, Lowenstein, Pedro R, Castro, Maria G
Published in Neuro-oncology (Charlottesville, Va.) (20.02.2020)
Published in Neuro-oncology (Charlottesville, Va.) (20.02.2020)
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Glycerol-3-phosphate acyltransferase 2 is essential for normal spermatogenesis
Garcia-Fabiani, Maria B, Montanaro, Mauro A, Stringa, Pablo, Lacunza, Ezequiel, Cattaneo, Elizabeth R, Santana, Marianela, Pellon-Maison, Magali, Gonzalez-Baro, Maria R
Published in Biochemical journal (15.09.2017)
Published in Biochemical journal (15.09.2017)
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Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies
Garcia-Fabiani, Maria B., Haase, Santiago, Comba, Andrea, Carney, Stephen, McClellan, Brandon, Banerjee, Kaushik, Alghamri, Mahmoud S., Syed, Faisal, Kadiyala, Padma, Nunez, Felipe J., Candolfi, Marianela, Asad, Antonela, Gonzalez, Nazareno, Aikins, Marisa E., Schwendeman, Anna, Moon, James J., Lowenstein, Pedro R., Castro, Maria G.
Published in Frontiers in oncology (08.06.2021)
Published in Frontiers in oncology (08.06.2021)
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Glycerol-3-phosphate acyltransferase 2 expression modulates cell roughness and membrane permeability: An atomic force microscopy study
Cattaneo, Elizabeth R, Prieto, Eduardo D, Garcia-Fabiani, Maria B, Montanaro, Mauro A, Guillou, Herve, Gonzalez-Baro, Maria R
Published in PloS one (06.12.2017)
Published in PloS one (06.12.2017)
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Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis
Garcia-Fabiani, Maria B, Montanaro, Mauro A, Lacunza, Ezequiel, Cattaneo, Elizabeth R, Coleman, Rosalind A, Pellon-Maison, Magali, Gonzalez-Baro, Maria R
Published in Biochemical journal (15.10.2015)
Published in Biochemical journal (15.10.2015)
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Inhibition of 2-hydroxyglutarate elicits metabolic reprogramming and mutant IDH1 glioma immunity in mice
Kadiyala, Padma, Carney, Stephen V, Gauss, Jessica C, Garcia-Fabiani, Maria B, Haase, Santiago, Alghamri, Mahmoud S, Núñez, Felipe J, Liu, Yayuan, Yu, Minzhi, Taher, Ayman, Nunez, Fernando M, Li, Dan, Edwards, Marta B, Kleer, Celina G, Appelman, Henry, Sun, Yilun, Zhao, Lili, Moon, James J, Schwendeman, Anna, Lowenstein, Pedro R, Castro, Maria G
Published in The Journal of clinical investigation (15.02.2021)
Published in The Journal of clinical investigation (15.02.2021)
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Immunotherapy for gliomas: shedding light on progress in preclinical and clinical development
Garcia-Fabiani, Maria B, Ventosa, Maria, Comba, Andrea, Candolfi, Marianela, Nicola Candia, Alejandro J, Alghamri, Mahmoud S, Kadiyala, Padma, Carney, Stephen, Faisal, Syed M, Schwendeman, Anna, Moon, James J, Scheetz, Lindsay, Lahann, Joerg, Mauser, Ava, Lowenstein, Pedro R, Castro, Maria G
Published in Expert opinion on investigational drugs (02.07.2020)
Published in Expert opinion on investigational drugs (02.07.2020)
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Prospects of biological and synthetic pharmacotherapies for glioblastoma
Altshuler, David B, Kadiyala, Padma, Nuñez, Felipe J, Nuñez, Fernando M, Carney, Stephen, Alghamri, Mahmoud S, Garcia-Fabiani, Maria B, Asad, Antonela S, Nicola Candia, Alejandro J, Candolfi, Marianela, Lahann, Joerg, Moon, James J, Schwendeman, Anna, Lowenstein, Pedro R, Castro, Maria G
Published in Expert opinion on biological therapy (03.03.2020)
Published in Expert opinion on biological therapy (03.03.2020)
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Evaluation of Biomarkers in Glioma by Immunohistochemistry on Paraffin-Embedded 3D Glioma Neurosphere Cultures
Núñez, Felipe J, Mendez, Flor M, Garcia-Fabiani, Maria B, Pardo, Joaquín, Edwards, Marta, Lowenstein, Pedro R, Castro, Maria G
Published in Journal of visualized experiments (09.01.2019)
Published in Journal of visualized experiments (09.01.2019)
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Abstract 869: Molecular characterization of a pediatric high-grade glioma (pHGG) mouse model harboring the H3.3 G34R mutation
Whalen, Matthew J., Garcia-Fabiani, Maria B., Núñez, Felipe J., Lowenstein, Pedro R., Castro, Maria G.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Therapeutic Efficacy of Immune Stimulatory Thymidine Kinase and fms-like Tyrosine Kinase 3 Ligand (TK/Flt3L) Gene Therapy in a Mouse Model of High-Grade Brainstem Glioma
Mendez, Flor, Kadiyala, Padma, Nunez, Felipe J, Carney, Stephen, Nunez, Fernando M, Gauss, Jessica C, Ravindran, Ramya, Pawar, Sheeba, Edwards, Marta, Garcia-Fabiani, Maria Belen, Haase, Santiago, Lowenstein, Pedro R, Castro, Maria G
Published in Clinical cancer research (01.08.2020)
Published in Clinical cancer research (01.08.2020)
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PDTM-20. THE HISTONE MUTATION H3.3-G34R ENCOUNTERED IN PEDIATRIC HIGH GRADE GLIOMA MODIFIES THE TUMOR IMMUNE MICROENVIRONMENT RENDERING IT MORE PERMISSIVE FOR IMMUNE MEDIATED THERAPIES
B Garcia-Fabiani, Maria, Kadiyala, Padma, Haase, Santiago, Alghamri, Mahmoud, Comba, Andrea, Nunez, Felipe, Whalen, Matthew, Lowenstein, Pedro, Castro, Maria
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2019)
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2019)
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Journal Article
Evaluation of Biomarkers in Glioma by Immunohistochemistry on Paraffin-Embedded 3D Glioma Neurosphere Cultures
Núñez, Felipe J., Mendez, Flor M., Garcia-Fabiani, Maria B., Pardo, Joaquín, Edwards, Marta, Lowenstein, Pedro R., Castro, Maria G.
Published in Journal of visualized experiments (09.01.2019)
Published in Journal of visualized experiments (09.01.2019)
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Epigenetic Reprogramming of Autophagy Drives Mutant IDH1 Glioma Progression and Response to Radiation
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Published in bioRxiv : the preprint server for biology (13.03.2024)
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Published in bioRxiv : the preprint server for biology (13.03.2024)
Journal Article
H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Pediatric High-Grade Gliomas
Garcia-Fabiani, Maria B, Haase, Santiago, Banerjee, Kaushik, McClellan, Brandon, Zhu, Ziwen, Mujeeb, Anzar, Li, Yingxiang, Yu, Jin, Kadiyala, Padma, Taher, Ayman, Núñez, Felipe J, Alghamri, Mahmoud S, Comba, Andrea, Mendez, Flor M, Nicola Candia, Alejandro J, Salazar, Brittany, Koschmann, Carl, Nunez, Fernando M, Edwards, Marta, Qin, Tingting, Sartor, Maureen A, Lowenstein, Pedro R, Castro, Maria G
Published in bioRxiv (13.06.2023)
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Published in bioRxiv (13.06.2023)
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IDH1R132H acts as a tumor suppressor in glioma via epigenetic upregulation of the DNA damage response
Nunez, Felipe J, Mendez, Flor M, Kadilaya, Padma, Alghamri, Mahmoud S, Savelieff, Masha, Koschmann, Carl, Anda-Alexandra Calinescu, Kamran, Neha, Patel, Rohin, Guo, Marissa Z, Carney, Stephen, Garcia-Fabiani, Maria B, Haase, Santiago, Edwards, Marta, Ljungman, Mats, Qin, Tingting, Sartor, Maureen, Tagett, Rebecca, Venneti, Sriram, Brosnan-Cashman, Jacqueline, Meeker, Alan, Gorbunova, Vera, Zhao, Lili, Kramer, Daniel, Zhang, Li, Lyssiotis, Costas A, Jones, Lindsey, Herting, Cameron, Ross, James, Hambardzumyan, Dolores, Hervey-Jumper, Shawn, Figueroa, Maria E, Lowenstein, Pedro R, Castro, Maria G
Published in bioRxiv (10.08.2018)
Published in bioRxiv (10.08.2018)
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