FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration
Alvarez‐Garcia, Oscar, Matsuzaki, Tokio, Olmer, Merissa, Miyata, Kohei, Mokuda, Sho, Sakai, Daisuke, Masuda, Koichi, Asahara, Hiroshi, Lotz, Martin K.
Published in Aging cell (01.10.2018)
Published in Aging cell (01.10.2018)
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Journal Article
Regulated in Development and DNA Damage Response 1 Deficiency Impairs Autophagy and Mitochondrial Biogenesis in Articular Cartilage and Increases the Severity of Experimental Osteoarthritis
Alvarez‐Garcia, Oscar, Matsuzaki, Tokio, Olmer, Merissa, Plate, Lars, Kelly, Jeffery W., Lotz, Martin K.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2017)
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Journal Article
Increased DNA Methylation and Reduced Expression of Transcription Factors in Human Osteoarthritis Cartilage
Alvarez‐Garcia, Oscar, Fisch, Kathleen M., Wineinger, Nathan E., Akagi, Ryuichiro, Saito, Masahiko, Sasho, Takahisa, Su, Andrew I., Lotz, Martin K.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2016)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2016)
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Journal Article
Transthyretin Deposition in Articular Cartilage: A Novel Mechanism in the Pathogenesis of Osteoarthritis
Akasaki, Yukio, Reixach, Natàlia, Matsuzaki, Tokio, Alvarez‐Garcia, Oscar, Olmer, Merissa, Iwamoto, Yukihide, Buxbaum, Joel N., Lotz, Martin K.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2015)
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Journal Article
Transthyretin deposition promotes progression of osteoarthritis
Matsuzaki, Tokio, Akasaki, Yukio, Olmer, Merissa, Alvarez‐Garcia, Oscar, Reixach, Natalia, Buxbaum, Joel N., Lotz, Martin K.
Published in Aging cell (01.12.2017)
Published in Aging cell (01.12.2017)
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Journal Article
Shared and Compartment‐Specific Processes in Nucleus Pulposus and Annulus Fibrosus During Intervertebral Disc Degeneration
Swahn, Hannah, Mertens, Jasmin, Olmer, Merissa, Myers, Kevin, Mondala, Tony S., Natarajan, Padmaja, Head, Steven R., Alvarez‐Garcia, Oscar, Lotz, Martin K.
Published in Advanced science (01.05.2024)
Published in Advanced science (01.05.2024)
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Journal Article
Age‐related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration
Alvarez‐Garcia, Oscar, Matsuzaki, Tokio, Olmer, Merissa, Masuda, Koichi, Lotz, Martin K.
Published in Journal of orthopaedic research (01.12.2017)
Published in Journal of orthopaedic research (01.12.2017)
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Journal Article
FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis
Matsuzaki, Tokio, Alvarez-Garcia, Oscar, Mokuda, Sho, Nagira, Keita, Olmer, Merissa, Gamini, Ramya, Miyata, Kohei, Akasaki, Yukio, Su, Andrew I, Asahara, Hiroshi, Lotz, Martin K
Published in Science translational medicine (14.02.2018)
Published in Science translational medicine (14.02.2018)
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Journal Article
FOXO1 and FOXO3 transcription factors have unique functions in meniscus development and homeostasis during aging and osteoarthritis
Lee, Kwang Il, Choi, Sungwook, Matsuzaki, Tokio, Alvarez-Garcia, Oscar, Olmer, Merissa, Grogan, Shawn P., D’Lima, Darryl D., Lotz, Martin K.
Published in Proceedings of the National Academy of Sciences - PNAS (11.02.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (11.02.2020)
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Journal Article
Antisense RNA Controls LRP1 Sense Transcript Expression through Interaction with a Chromatin-Associated Protein, HMGB2
Yamanaka, Yasunari, Faghihi, Mohammad Ali, Magistri, Marco, Alvarez-Garcia, Oscar, Lotz, Martin, Wahlestedt, Claes
Published in Cell reports (Cambridge) (12.05.2015)
Published in Cell reports (Cambridge) (12.05.2015)
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Journal Article
Inverse correlation between endogenous melatonin levels and oxidative damage in some tissues of SAM P8 mice
Lardone, Patricia J., Alvarez-García, Óscar, Carrillo-Vico, Antonio, Vega-Naredo, Ignacio, Caballero, Beatriz, Guerrero, Juan M., Coto-Montes, Ana
Published in Journal of pineal research (01.03.2006)
Published in Journal of pineal research (01.03.2006)
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Journal Article
Enhancement of the benthic communities around an isolated island in the Antarctic Ocean
Saiz, José I., Anadón, Nuria, Cristobo, Javier, García-Alvarez, Oscar, García-Castrillo, Gerardo, López, Eduardo, Palacín, Cruz, Troncoso, Jesús S., Ramos, Ana
Published in Acta oceanologica Sinica (01.06.2013)
Published in Acta oceanologica Sinica (01.06.2013)
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Journal Article
Coexpression of MT1 and RORα1 melatonin receptors in the Syrian hamster Harderian gland
Tomás-Zapico, Cristina, Antonio Boga, José, Caballero, Beatriz, Vega-Naredo, Ignacio, Sierra, Verónica, Álvarez-García, Óscar, Tolivia, Delio, Josefa Rodríguez-Colunga, María, Coto-Montes, Ana
Published in Journal of pineal research (01.08.2005)
Published in Journal of pineal research (01.08.2005)
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Journal Article
Metabolic Benefit of Chronic Caloric Restriction and Activation of Hypothalamic AGRP/NPY Neurons in Male Mice Is Independent of Ghrelin
Rogers, Nicole H, Walsh, Heidi, Alvarez-Garcia, Oscar, Park, Seongjoon, Gaylinn, Bruce, Thorner, Michael O, Smith, Roy G
Published in Endocrinology (Philadelphia) (01.04.2016)
Published in Endocrinology (Philadelphia) (01.04.2016)
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Journal Article
Rapamycin retards growth and causes marked alterations in the growth plate of young rats
Alvarez-Garcia, Oscar, Carbajo-Pérez, Eduardo, Garcia, Enrique, Gil, Helena, Molinos, Ines, Rodriguez, Julian, Ordoñez, Flor A, Santos, Fernando
Published in Pediatric nephrology (Berlin, West) (01.07.2007)
Published in Pediatric nephrology (Berlin, West) (01.07.2007)
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Journal Article
127 - THROMBOSPONDIN IS A CRITICAL PATHOGENIC SIGNAL THAT PROMOTES FIBROSIS, ANGIOGENESIS AND NEURONAL SPROUTING DURING INTERVERTEBRAL DISC DEGENERATION
Swahn, Hannah, Mertens, Jasmin, Myers, Kevin, Alvarez-Garcia, Oscar, Mondala, Tony S., Natarajan, Padmaja, Head, Steven R., Lotz, Martin K.
Published in Osteoarthritis and cartilage (01.04.2024)
Published in Osteoarthritis and cartilage (01.04.2024)
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Journal Article
THROMBOSPONDIN IS A CRITICAL PATHOGENIC SIGNAL THAT PROMOTES FIBROSIS, ANGIOGENESIS AND NEURONAL SPROUTING DURING INTERVERTEBRAL DISC DEGENERATION
Swahn, Hannah, Mertens, Jasmin, Myers, Kevin, Alvarez-Garcia, Oscar, Mondala, Tony S., Natarajan, Padmaja, Head, Steven R., Lotz, Martin K.
Published in Osteoarthritis and cartilage (01.04.2024)
Published in Osteoarthritis and cartilage (01.04.2024)
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Journal Article
Identification of transcription factors responsible for dysregulated networks in human osteoarthritis cartilage by global gene expression analysis
Fisch, K.M., Gamini, R., Alvarez-Garcia, O., Akagi, R., Saito, M., Muramatsu, Y., Sasho, T., Koziol, J.A., Su, A.I., Lotz, M.K.
Published in Osteoarthritis and cartilage (01.11.2018)
Published in Osteoarthritis and cartilage (01.11.2018)
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Journal Article