Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice
Lim, Ryan G, Salazar, Lisa L, Wilton, Daniel K, King, Alvin R, Stocksdale, Jennifer T, Sharifabad, Delaram, Lau, Alice L, Stevens, Beth, Reidling, Jack C, Winokur, Sara T, Casale, Malcolm S, Thompson, Leslie M, Pardo, Mónica, Díaz-Barriga, A Gerardo García, Straccia, Marco, Sanders, Phil, Alberch, Jordi, Canals, Josep M, Kaye, Julia A, Dunlap, Mariah, Jo, Lisa, May, Hanna, Mount, Elliot, Anderson-Bergman, Cliff, Haston, Kelly, Finkbeiner, Steven, Kedaigle, Amanda J, Gipson, Theresa A, Yildirim, Ferah, Ng, Christopher W, Milani, Pamela, Housman, David E, Fraenkel, Ernest, Allen, Nicholas D, Kemp, Paul J, Atwal, Ranjit Singh, Biagioli, Marta, Gusella, James F, MacDonald, Marcy E, Akimov, Sergey S, Arbez, Nicolas, Stewart, Jacqueline, Ross, Christopher A, Mattis, Virginia B, Tom, Colton M, Ornelas, Loren, Sahabian, Anais, Lenaeus, Lindsay, Mandefro, Berhan, Sareen, Dhruv, Svendsen, Clive N
Published in Nature neuroscience (01.05.2017)
Published in Nature neuroscience (01.05.2017)
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Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons
Telezhkin, Vsevolod, Straccia, Marco, Yarova, Polina, Pardo, Monica, Yung, Sun, Vinh, Ngoc-Nga, Hancock, Jane M., Barriga, Gerardo Garcia-Diaz, Brown, David A., Rosser, Anne E., Brown, Jonathan T., Canals, Josep M., Randall, Andrew D., Allen, Nicholas D., Kemp, Paul J.
Published in Pflügers Archiv (01.09.2018)
Published in Pflügers Archiv (01.09.2018)
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Inflammation in multiple sclerosis induces a specific reactive astrocyte state driving non‐cell‐autonomous neuronal damage
Matute‐Blanch, Clara, Brito, Verónica, Midaglia, Luciana, Villar, Luisa M, Garcia‐Diaz Barriga, Gerardo, Guzman de la Fuente, Alerie, Borrás, Eva, Fernández‐García, Sara, Calvo‐Barreiro, Laura, Miguez, Andrés, Costa‐Frossard, Lucienne, Pinteac, Rucsanda, Sabidó, Eduard, Alberch, Jordi, Fitzgerald, Denise C., Montalban, Xavier, Comabella, Manuel
Published in Clinical and translational medicine (01.05.2022)
Published in Clinical and translational medicine (01.05.2022)
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Systematic Quantification of Synapses in Primary Neuronal Culture
Verstraelen, Peter, Garcia-Diaz Barriga, Gerardo, Verschuuren, Marlies, Asselbergh, Bob, Nuydens, Rony, Larsen, Peter H., Timmermans, Jean-Pierre, De Vos, Winnok H.
Published in iScience (25.09.2020)
Published in iScience (25.09.2020)
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High-throughput microscopy exposes a pharmacological window in which dual leucine zipper kinase inhibition preserves neuronal network connectivity
Verschuuren, Marlies, Verstraelen, Peter, García-Díaz Barriga, Gerardo, Cilissen, Ines, Coninx, Emma, Verslegers, Mieke, Larsen, Peter H, Nuydens, Rony, De Vos, Winnok H
Published in Acta neuropathologica communications (04.06.2019)
Published in Acta neuropathologica communications (04.06.2019)
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Quantitative high-throughput gene expression profiling of human striatal development to screen stem cell-derived medium spiny neurons
Straccia, Marco, Garcia-Diaz Barriga, Gerardo, Sanders, Phil, Bombau, Georgina, Carrere, Jordi, Mairal, Pedro Belio, Vinh, Ngoc-Nga, Yung, Sun, Kelly, Claire M, Svendsen, Clive N, Kemp, Paul J, Arjomand, Jamshid, Schoenfeld, Ryan C, Alberch, Jordi, Allen, Nicholas D, Rosser, Anne E, Canals, Josep M
Published in Molecular therapy. Methods & clinical development (01.01.2015)
Published in Molecular therapy. Methods & clinical development (01.01.2015)
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Increased translation as a novel pathogenic mechanism in Huntington's disease
Creus-Muncunill, Jordi, Badillos-Rodríguez, Raquel, Garcia-Forn, Marta, Masana, Mercè, Garcia-Díaz Barriga, Gerardo, Guisado-Corcoll, Anna, Alberch, Jordi, Malagelada, Cristina, Delgado-García, José M, Gruart, Agnès, Pérez-Navarro, Esther
Published in Brain (London, England : 1878) (01.10.2019)
Published in Brain (London, England : 1878) (01.10.2019)
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A FBN1 3′UTR mutation variant is associated with endoplasmic reticulum stress in aortic aneurysm in Marfan syndrome
Siegert, Anna-Maria, García Díaz-Barriga, Gerardo, Esteve-Codina, Anna, Navas-Madroñal, Miquel, Gorbenko del Blanco, Darya, Alberch, Jordi, Heath, Simon, Galán, María, Egea, Gustavo
Published in Biochimica et biophysica acta. Molecular basis of disease (01.01.2019)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.01.2019)
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Serum Amyloid A3 Fuels a Feed-Forward Inflammatory Response to the Bacterial Amyloid Curli in the Enteric Nervous System
Verstraelen, Peter, Van Remoortel, Samuel, De Loose, Nouchin, Verboven, Rosanne, Garcia-Diaz Barriga, Gerardo, Christmann, Anne, Gries, Manuela, Bessho, Shingo, Li, Jing, Guerra, Carmen, Tükel, Çagla, Martinez, Sales Ibiza, Schäfer, Karl-Herbert, Timmermans, Jean-Pierre, De Vos, Winnok H.
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
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Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis
Pulido-Salgado, Marta, Vidal-Taboada, Jose M, Garcia Diaz-Barriga, Gerardo, Serratosa, Joan, Valente, Tony, Castillo, Paola, Matalonga, Jonathan, Straccia, Marco, Canals, Josep M, Valledor, Annabel, Solà, Carme, Saura, Josep
Published in Journal of neuroinflammation (16.03.2017)
Published in Journal of neuroinflammation (16.03.2017)
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M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington's disease
Fernández-García, Sara, Conde-Berriozabal, Sara, García-García, Esther, Gort-Paniello, Clara, Bernal-Casas, David, García-Díaz Barriga, Gerardo, López-Gil, Javier, Muñoz-Moreno, Emma, Soria, Guadalupe, Campa, Leticia, Artigas, Francesc, Rodríguez, Manuel José, Alberch, Jordi, Masana, Mercè
Published in eLife (05.10.2020)
Published in eLife (05.10.2020)
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7,8-dihydroxyflavone ameliorates cognitive and motor deficits in a Huntington's disease mouse model through specific activation of the PLCγ1 pathway
García-Díaz Barriga, Gerardo, Giralt, Albert, Anglada-Huguet, Marta, Gaja-Capdevila, Nuria, Orlandi, Javier G, Soriano, Jordi, Canals, Josep-Maria, Alberch, Jordi
Published in Human molecular genetics (15.08.2017)
Published in Human molecular genetics (15.08.2017)
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Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis
Fraire, Juan C., Houthaeve, Gaëlle, Liu, Jing, Raes, Laurens, Vermeulen, Lotte, Stremersch, Stephan, Brans, Toon, García-Díaz Barriga, Gerardo, De Keulenaer, Sarah, Van Nieuwerburgh, Filip, De Rycke, Riet, Vandesompele, Jo, Mestdagh, Pieter, Raemdonck, Koen, De Vos, Winnok H., De Smedt, Stefaan, Braeckmans, Kevin
Published in Journal of controlled release (10.03.2020)
Published in Journal of controlled release (10.03.2020)
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Transient nuclear lamin A/C accretion aids in recovery from vapor nanobubble-induced permeabilisation of the plasma membrane
Houthaeve, Gaëlle, García-Díaz Barriga, Gerardo, Stremersch, Stephan, De Keersmaecker, Herlinde, Fraire, Juan, Vandesompele, Jo, Mestdagh, Pieter, De Smedt, Stefaan, Braeckmans, Kevin, De Vos, Winnok H.
Published in Cellular and molecular life sciences : CMLS (01.01.2022)
Published in Cellular and molecular life sciences : CMLS (01.01.2022)
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Prostaglandin E2 EP2 activation reduces memory decline in R6/1 mouse model of Huntington's disease by the induction of BDNF-dependent synaptic plasticity
Anglada-Huguet, Marta, Vidal, Laura, Giralt, Albert, García-Díaz Barriga, Gerardo, Xifró, Xavier, Alberch, Jordi
Published in Neurobiology of disease (01.11.2016)
Published in Neurobiology of disease (01.11.2016)
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Journal Article
Pharmacogenetic modulation of STEP improves motor and cognitive function in a mouse model of Huntington's disease
García-Forn, Marta, Martínez-Torres, Sara, García-Díaz Barriga, Gerardo, Alberch, Jordi, Milà, Montse, Azkona, Garikoitz, Pérez-Navarro, Esther
Published in Neurobiology of disease (01.12.2018)
Published in Neurobiology of disease (01.12.2018)
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Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons
Martín-Ibáñez, Raquel, Pardo, Mónica, Giralt, Albert, Miguez, Andrés, Guardia, Inés, Marion-Poll, Lucile, Herranz, Cristina, Esgleas, Miriam, Garcia-Díaz Barriga, Gerardo, Edel, Michael J, Vicario-Abejón, Carlos, Alberch, Jordi, Girault, Jean-Antoine, Chan, Susan, Kastner, Philippe, Canals, Josep M
Published in Development (Cambridge) (15.04.2017)
Published in Development (Cambridge) (15.04.2017)
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Journal Article
Serum Amyloid A3 Fuels a Feed-Forward Inflammatory Response to the Bacterial Amyloid Curli in the Enteric Nervous SystemSummary
Peter Verstraelen, Samuel Van Remoortel, Nouchin De Loose, Rosanne Verboven, Gerardo Garcia-Diaz Barriga, Anne Christmann, Manuela Gries, Shingo Bessho, Jing Li, Carmen Guerra, Çagla Tükel, Sales Ibiza Martinez, Karl-Herbert Schäfer, Jean-Pierre Timmermans, Winnok H. De Vos
Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
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Published in Cellular and molecular gastroenterology and hepatology (01.01.2024)
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Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis
Pulido Salgado, Marta, Vidal Taboada, José Manuel, Garcia Diaz-Barriga, Gerardo, Serratosa i Serdà, Joan, Valente, Tony, Castillo, Paola, Matalonga, Jonathan, Straccia, Marco, Canals i Coll, Josep M, Valledor Fernández, Annabel, Solà i Subirana, Carme, Saura Martí, Josep
Published in Journal of neuroinflammation (16.03.2017)
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Published in Journal of neuroinflammation (16.03.2017)
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