Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand
Côrte-Real, Leonor, Karas, Brittany, Gírio, Patrícia, Moreno, Alexis, Avecilla, Fernando, Marques, Fernanda, Buckley, Brian T., Cooper, Keith R., Doherty, Cathleen, Falson, Pierre, Garcia, M. Helena, Valente, Andreia
Published in European journal of medicinal chemistry (01.02.2019)
Published in European journal of medicinal chemistry (01.02.2019)
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Journal Article
A new family of iron(II)-cyclopentadienyl compounds shows strong activity against colorectal and triple negative breast cancer cells
Pilon, Adhan, Brás, Ana Rita, Côrte-Real, Leonor, Avecilla, Fernando, Costa, Paulo J., Preto, Ana, Garcia, M. Helena, Valente, Andreia
Published in Molecules (Basel, Switzerland) (30.03.2020)
Published in Molecules (Basel, Switzerland) (30.03.2020)
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Journal Article
Ruthenium–Cyclopentadienyl Bipyridine–Biotin Based Compounds: Synthesis and Biological Effect
Côrte-Real, Leonor, Karas, Brittany, Brás, Ana Rita, Pilon, Adhan, Avecilla, Fernando, Marques, Fernanda, Preto, Ana, Buckley, Brian T, Cooper, Keith R, Doherty, Cathleen, Garcia, M. Helena, Valente, Andreia
Published in Inorganic chemistry (15.07.2019)
Published in Inorganic chemistry (15.07.2019)
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Journal Article
Binding of RuCp complexes with human apo-transferrin: fluorescence spectroscopy and molecular docking methods
Santos, Filipa C., Costa, Paulo J., Garcia, M. Helena, Morais, Tânia S.
Published in Biometals (01.10.2021)
Published in Biometals (01.10.2021)
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Journal Article
Polymer “ruthenium-cyclopentadienyl” conjugates - New emerging anti-cancer drugs
Moreira, Tiago, Francisco, Rita, Comsa, Elisabeta, Duban-Deweer, Sophie, Labas, Valérie, Teixeira-Gomes, Ana-Paula, Combes-Soia, Lucie, Marques, Fernanda, Matos, António, Favrelle, Audrey, Rousseau, Cyril, Zinck, Philippe, Falson, Pierre, Garcia, M. Helena, Preto, Ana, Valente, Andreia
Published in European journal of medicinal chemistry (15.04.2019)
Published in European journal of medicinal chemistry (15.04.2019)
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Journal Article
In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model
Mendes, Nuno, Tortosa, Francisco, Valente, Andreia, Marques, Fernanda, Matos, António, Morais, Tânia S, Tomaz, Ana Isabel, Gärtner, Fátima, Garcia, M Helena
Published in Anti-cancer agents in medicinal chemistry (2017)
Published in Anti-cancer agents in medicinal chemistry (2017)
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Journal Article
New copper(I) and heteronuclear copper(I)–ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity
Lopes, João, Alves, David, Morais, Tânia S., Costa, Paulo J., Piedade, M. Fátima M., Marques, Fernanda, Villa de Brito, Maria J., Helena Garcia, M.
Published in Journal of inorganic biochemistry (01.04.2017)
Published in Journal of inorganic biochemistry (01.04.2017)
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Journal Article
Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes
Côrte-Real, Leonor, Mendes, Filipa, Coimbra, Joana, Morais, Tânia S., Tomaz, Ana Isabel, Valente, Andreia, Garcia, M. Helena, Santos, Isabel, Bicho, Manuel, Marques, Fernanda
Published in Journal of biological inorganic chemistry (01.08.2014)
Published in Journal of biological inorganic chemistry (01.08.2014)
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Journal Article
Methyl-cyclopentadienyl Ruthenium Compounds with 2,2′-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential
Côrte-Real, Leonor, Teixeira, Ricardo G, Gírio, Patrícia, Comsa, Elisabeta, Moreno, Alexis, Nasr, Rachad, Baubichon-Cortay, Hélène, Avecilla, Fernando, Marques, Fernanda, Robalo, M. Paula, Mendes, Paulo, Ramalho, João P. Prates, Garcia, M. Helena, Falson, Pierre, Valente, Andreia
Published in Inorganic chemistry (16.04.2018)
Published in Inorganic chemistry (16.04.2018)
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Journal Article
New copper() complexes selective for prostate cancer cells
Machado, João Franco, Sequeira, Diogo, Marques, Fernanda, Piedade, M. Fátima M, Villa de Brito, Maria J, Helena Garcia, M, Fernandes, Alexandra R, Morais, Tânia S
Published in Dalton transactions : an international journal of inorganic chemistry (15.09.2020)
Published in Dalton transactions : an international journal of inorganic chemistry (15.09.2020)
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Journal Article
Important cytotoxic and cytostatic effects of new copper(i)-phosphane compounds with N,N, N,O and N,S bidentate ligands
Morais, Tânia S, Jousseaume, Yann, M Piedade, M Fátima, Roma-Rodrigues, Catarina, Fernandes, Alexandra R, Marques, Fernanda, Villa de Brito, Maria J, Garcia, M Helena
Published in Dalton transactions : an international journal of inorganic chemistry (2018)
Published in Dalton transactions : an international journal of inorganic chemistry (2018)
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Journal Article
Biotinylated polymer-ruthenium conjugates: in vitro and in vivo studies in a triple-negative breast cancer model
Côrte-Real, Leonor, Brás, Ana Rita, Pilon, Adhan, Mendes, Nuno Miguel Morais, Ribeiro, Ana Sofia, Martins, Tiago D., Farinha, José Paulo S., Oliveira, M. Conceição, Gärtner, Fátima, Garcia, M. Helena, Preto, Ana, Valente, Andreia
Published in Pharmaceutics (30.06.2022)
Published in Pharmaceutics (30.06.2022)
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Journal Article
Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells
Teixeira, Ricardo G., Brás, Ana Rita, Côrte-Real, Leonor, Tatikonda, Rajendhraprasad, Sanches, Anabela, Robalo, M. Paula, Avecilla, Fernando, Moreira, Tiago, Garcia, M. Helena, Haukka, Matti, Preto, Ana, Valente, Andreia
Published in European journal of medicinal chemistry (01.01.2018)
Published in European journal of medicinal chemistry (01.01.2018)
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Journal Article
Novel "ruthenium cyclopentadienyl"-peptide conjugate complexes against human FGFR(+) breast cancer
Franco Machado, João, Machuqueiro, Miguel, Marques, Fernanda, Robalo, M. Paula, Piedade, M. Fátima M, Garcia, M. Helena, Correia, João D. G, Morais, Tânia S
Published in Dalton transactions : an international journal of inorganic chemistry (14.05.2020)
Published in Dalton transactions : an international journal of inorganic chemistry (14.05.2020)
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Journal Article
Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites
Fernández, Mariana, Arce, Esteban Rodríguez, Sarniguet, Cynthia, Morais, Tânia S., Tomaz, Ana Isabel, Azar, Claudio Olea, Figueroa, Roberto, Diego Maya, J., Medeiros, Andrea, Comini, Marcelo, Helena Garcia, M., Otero, Lucía, Gambino, Dinorah
Published in Journal of inorganic biochemistry (01.12.2015)
Published in Journal of inorganic biochemistry (01.12.2015)
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Journal Article
[RuII(η5-C5H5)(bipy)(PPh3)]+, a promising large spectrum antitumor agent: Cytotoxic activity and interaction with human serum albumin
Tomaz, Ana Isabel, Jakusch, Tamás, Morais, Tânia S., Marques, Fernanda, de Almeida, Rodrigo F.M., Mendes, Filipa, Enyedy, Éva A., Santos, Isabel, Pessoa, João Costa, Kiss, Tamás, Garcia, M. Helena
Published in Journal of inorganic biochemistry (01.12.2012)
Published in Journal of inorganic biochemistry (01.12.2012)
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Journal Article
Studies on the mechanism of action of antitumor bis(aminophenolate) ruthenium(III) complexes
Dömötör, Orsolya, de Almeida, Rodrigo F.M., Côrte-Real, Leonor, Matos, Cristina P., Marques, Fernanda, Matos, António, Real, Carla, Kiss, Tamás, Enyedy, Éva Anna, Helena Garcia, M., Tomaz, Ana Isabel
Published in Journal of inorganic biochemistry (01.03.2017)
Published in Journal of inorganic biochemistry (01.03.2017)
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Journal Article
First heterobimetallic Cu()-dppf complexes designed for anticancer applications: synthesis, structural characterization and cytotoxicity
Bravo, Catarina, Robalo, M. Paula, Marques, Fernanda, Fernandes, Alexandra R, Sequeira, Diogo A, Piedade, M. Fátima, Garcia, M. Helena, de Brito, Maria J. Villa, Morais, Tânia S
Published in New journal of chemistry (21.08.2019)
Published in New journal of chemistry (21.08.2019)
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Journal Article
New water-soluble ruthenium(II) cytotoxic complex: Biological activity and cellular distribution
Morais, Tânia S., Santos, Filipa C., Jorge, Tiago F., Côrte-Real, Leonor, Madeira, Paulo J. Amorim, Marques, Fernanda, Robalo, M. Paula, Matos, António, Santos, Isabel, Garcia, M. Helena
Published in Journal of inorganic biochemistry (01.01.2014)
Published in Journal of inorganic biochemistry (01.01.2014)
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Journal Article
The key role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: Ranging from non-cytotoxic to highly cytotoxic compounds
Côrte-Real, Leonor, Robalo, M. Paula, Marques, Fernanda, Nogueira, Guilherme, Avecilla, Fernando, J.L. Silva, Tiago, C. Santos, Filipa, Tomaz, A. Isabel, Garcia, M. Helena, Valente, Andreia
Published in Journal of inorganic biochemistry (01.09.2015)
Published in Journal of inorganic biochemistry (01.09.2015)
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Journal Article